Methycobal® is a mecobalamin preparation for treatment of peripheral neuropathies. Methycobal® contains mecobalamin, a vitamin B12 coenzyme that occurs in the blood and the cerebrospinal fluid. It is taken up by nerve tissues more actively and extensively than other homologue of vitamin B12. Biochemically, Methycobal® accelerates the metabolic pathways of nucleic acids, proteins and lipids through its involvement in the transmethylation reaction. Thus, it exerts a repairing effect on injured nerve tissues. Clinically, Methycobal® is the first pharmaceutical product that has been shown, by double-blind clinical studies, to be effective and useful for the treatment of numbness, pain, and paralysis due to peripheral neuropathies such as Diabetic Neuropathy and Carpal Tunnel Syndrome.