218-TRIAL-Abbocin Injection contains Tobramycin, Inj | belongs to Aminoglycoside
IV: Infuse over 30-60 min. Give penicillins or cephalosporins at least 1 hour apart from tobramycin.Reconstitution: Standard diluent: Dose/100 mL NS; minimum volume: 50 mL NSCompatibility: Stable in dextran 40 10% in dextrose, D5NS, D5W, D10W, mannitol 20%, LR, NS. Don’t mix tobramycin in same solution with parenteral aminoglycosides or beta lactam antibiotics because mutual inactivation may occur.Y-site administration:Drug to Drug IV Compatibility: Acyclovir, amikacin, amiodarone, aztreonam, bumetanide, calcium gluconate, ciprofloxacin, cisatracurium, diltiazem, diphenhydramine, dobutamine, dopamine, enalapril, epinephrine, esmolol, famotidine, fentanyl, fluconazole, furosemide, gentamicin, hydromorphone, imipenem, labetalol, levofloxacin, linezolid, lorazepam, magnesium sulphate, methylprednisolone, metoclopramide, midazolam, milrinone, nitroglycerin, nitroprusside, norepinephrine, ondansetron, phenylephrine, vancomycin, vasopressin.Drug to Drug IV Incompatibility: Allopurinol, amphotericin B cholesteryl sulphate complex, azithromycin, cefoperazone, ceftriaxone, dexamethasone, heparin, hetastarch, indomethacin, lansoprazole, piperacillin/tazobactam, propofol, sargramostim.In syringe: Incompatible with cefamandole, clindamycin, heparin.When admixed: Incompatible with cefamandole, cefepime, cefotaxime, cefotetan, floxacillin, heparin, penicillins.Stability: Stable at room temperature as the dry powder. Reconstituted solution remains stable for 24 hours at room temperature and 96 hours when refrigerated.
Voice alteration, cough, dyspnoea, nausea. Rarely, bronchospasm, tinnitus, dysphonia, lung disorders, laryngitis, sputum discolouration, GI upset, rhinitis, malaise, myalgia, hearing loss, dysgeusia, rash, haemoptysis, epistaxis, chest pain, pyrexia, nasal congestion.
Adults: 3-5 mg/kg daily in three or four divided doses by IM/IV inj or infusion. Children: Neonates, up to 4 mg/kg daily in two equal doses; others, 6-7.5 mg/kg daily in 3 or 4 divided doses.Bone Infection: IM/IV: Adults: 3 mg/kg/day given every 8 hr. Max: 5 mg/kg/day in 3-4 doses. Reduce to 3 mg/kg/day as soon as clinically indicated. Children: gt;1 wk: 2-2.5 mg/kg every 8 hr or 1.5-1.89 mg/kg every 6 hr. 1 wk or less: Up to 2 mg/kg every 12 hr.Lower Respiratory Infection, Meningitis & Septicaemia: IV: Adults: 3 mg/kg/day given every 8 hr. Max: 5 mg/kg/day in 3-4 doses. Reduce to 3 mg/kg/day as soon as clinically indicated. Children: gt;1 wk: 2-2.5 mg/kg every 8 hr or 1.5-1.89 mg/kg every 6 hr. lt;1 wk: Up to 2 mg/kg every 12 hr.
One of the following licensed pharmacy from the nearest location will deliver 218-TRIAL-Abbocin Injection 20 mg 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.
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