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Information on this page was last modified on : 2019/09/28 5:48:11 PM

2SUM 500mg Injection Vial

, This drug requires a valid prescription from PMDC registered health practitioner.
Manufactured by

Cefoperazone:500mg + Sulbactam:500mg | Cephalosporins

Manufactured / Marketed By : Sami

Product Form : Injection

Pack Size : Vial

Ingredients : Cefoperazone:500mg + Sulbactam:500mg

Generic Category : Cephalosporins

Product SKUdis_7900
Drug Strength
Pack size

Side effects

Major & minor side effects for 2SUM 500mg Injection Vial

  • Headache
  • Nausea and Vomiting
  • Diarrhea
  • Rash
  • Itching
  • Blood in urine
  • Decrease in blood cell count
  • Gastrointestinal side effects
  • Chills
  • Injection site Thrombophlebitis
  • Seizures
  • Injection site pain

Uses of 2SUM 500mg Injection Vial

What is it prescribed for?

  • Urinary tract infections

    This medicine is used in the treatment of upper and lower urinary tract infections caused by susceptible bacteria such as Escherichia coli, Pseudomonas aeruginosa, etc.

  • Respiratory Tract Infection

    This medicine is used in the treatment of upper and lower respiratory tract infections caused by susceptible bacteria such as Staphylococcus aureus, Escherichia coli, Klebsiella species, Proteus mirabilis, Enterobacter species, etc.

  • Intra-abdominal Infections

    This medicine is used in the treatment of intra-abdominal infections such as peritonitis, cholecystitis, cholangitis, etc. caused by susceptible bacteria such as Escherichia coli, Pseudomonas aeruginosa, etc.

  • Bacterial Septicemia

    This medicine is used in the treatment of bacterial septicemia which is an infection of the blood that may be caused by bacteria such as Pseudomonas aeruginosa, Haemophilus influenzae, Escherichia coli, etc.

  • Skin and Soft tissue infections

    This medicine is used in the treatment of skin and soft tissue infections caused by bacteria such as Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, etc.

  • Gynecologic infections

    This medicine is used in the treatment of gynecologic infections such as endometritis, pelvic inflammatory disease, gonorrhea, etc. caused by susceptible bacteria such as Neisseria gonorrhoeae, Staphylococcus epidermidis, Streptococcus agalactiae, Escherichia coli, etc.

Concerns

Frequently asked questions

  • Onset of action

    The effect of this medicine can be observed rapidly after an intravenous or intramuscular administration.The effect of this medicine can be observed rapidly after an intravenous or intramuscular administration.The effect of this medicine can be observed rapidly after an intravenous or intramuscular administration.

  • Duration of Effect

    The amount of time for which this medicine remains active in the body is not clinically established.

  • Safe with Alchohol?

    Use of this medicine within 48-72 hours of alcohol consumption may cause a disulfiram like-reaction. This reaction is characterized by symptoms such as severe vomiting, abdominal pain, headache, palpitations, difficulty in breathing, sweating, increased heart rate, etc. Consumption of alcohol is not recommended during treatment with this medicine and for several days after the therapy has been stopped. Any unusual symptoms should be reported to the doctor on priority. It is advised that you inform your doctor if you have consumed alcohol before beginning therapy with this medicine.

  • Is it habit forming?

    No habit-forming tendencies were reported.

  • Usage in pregnancy?

    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

When not to use?

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to cefoperazone, sulbactam, other beta-lactam antibiotics, or any other inactive ingredients present along with these medicines.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

  • Breast-feeding

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Warnings

Warnings for special population
  • Renal impairment

    This medicine should be used with caution in patients with a known history of renal impairment due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

  • Intravenous Use

    When administered as an intravenous infusion, this medicine should be administered over a duration of 15 to 60 minutes. When administered as an intravenous injection, this medicine should be administered over a minimum of 3 minutes.

  • Drug resistance

    Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and may even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

  • Clostridium difficile-associated Diarrhea

    Inform the doctor immediately in case of severe and persistent diarrhea. Antibiotic therapy will cause an imbalance in the normal microbial flora in the large intestine. This may decrease the gut-friendly bacteria and may promote the growth of a bacteria called Clostridium difficile, resulting in diarrhea. Appropriate corrective measures and replacement with a suitable alternative may be necessary based on the clinical condition.

  • Liver diseases

    This medicine should be used with extreme caution in patients with a known history of liver diseases or active liver diseases due to the increased risk of serious adverse effects. Close monitoring of liver function is recommended for such patients. The dose of cefoperazone should not exceed 4 g/day for such patients unless specifically required and only with close monitoring of serum cefoperazone concentrations and liver function. In patients with liver and renal function impairment, the cefoperazone dose should not exceed 2 g/day.

  • Electrolyte imbalance

    This medicine should be used with caution in patients with a known history of electrolyte imbalance since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Close monitoring of electrolyte levels, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

  • Epilepsy

    This medicine should be used with caution in patients with a known history of epilepsy due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Dosage

  • Missed Dose

    Since this medicine is administered by a qualified health care professional in the clinical or hospital setting, the likelihood of a missed dose is very low.

  • Overdose

    Since this medicine is administered in the hospital or clinical setting by a qualified health care professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions

Interaction with Medicines
  • Aminoglycoside antibiotics severe
  • Loop diuretics severe
  • Anticoagulants severe
  • Probenecid
Disease interactions
  • This medicine should be used with caution in patients with a known history of renal diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Lab interactions

General Instructions

This medicine should be administered by a qualified health care professional in the clinical or hospital setting. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Report any undesirable side effects to the doctor promptly.

Other details

  • Usage does not depend on food timings
  • To be taken as instructed by doctor
  • Does not cause sleepiness

How it works

Cefoperazone interferes with the bacterial cell wall formation and stops the growth of bacteria. Sulbactam inhibits some chemicals produced by the bacteria and makes the bacteria more sensitive to cefoperazone activity.

References

One of the following licensed pharmacy from the nearest location will deliver 2SUM 500mg Injection Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

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