3-ZONE 250mg Injection Vial

Side effects

Major & minor side effects for 3-ZONE 250mg Injection Vial

• Black or tarry stools Severe
• Chest pain Severe
• Fever
• Difficulty or painful urination
• Sore throat
• Diarrhea
• Abdominal pain
• Dizziness
• Swelling of face, lips, eyelids, tongue, hands and feet
• Acid or sour stomach
• Change in taste
• Excessive air or gas in stomach

Uses of 3-ZONE 250mg Injection Vial

What is it prescribed for?

• Bacterial Meningitis

  3-ZONE 250mg Injection Vial is used in the treatment of meningitis, which is an inflammation of the protective membranes that surround the brain and spinal cord. This infection may be caused by Streptococcus pneumoniae or Neisseria meningitidis.

• Bacterial Septicemia

  3-ZONE 250mg Injection Vial is used in the treatment of septicemia which is an infection of the blood caused by Staphylococci and Streptococcus pyogenes.

• Gonococcal Infection

  3-ZONE 250mg Injection Vial is used in the treatment of gonococcal infection which is a sexually transmitted bacterial infection caused by Neisseria gonorrhoeae.

• Urinary Tract Infection

  3-ZONE 250mg Injection Vial is used in the treatment of infections of the urinary tract caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.

• Pneumonia

  3-ZONE 250mg Injection Vial is used in the treatment of community-acquired pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.

• Bone and joint infections

  3-ZONE 250mg Injection Vial is used in the treatment of bone and joint infections such as septic arthritis and osteomyelitis caused by Staphylococci and Streptococci species.

• Skin and structure Infection

  3-ZONE 250mg Injection Vial is used in the treatment of Skin and structure infections such as cellulitis, wound infection and cutaneous abscesses caused by Streptococcus pyogenes and Staphylococcus aureus.

When not to use?

• Allergy

  This medicine is not recommended for use in patients with a known allergy to 3-ZONE 250mg Injection Vial or any other Beta-lactam antibiotics such as penicillins or cephalosporins.

• Lidocaine

  3-ZONE 250mg Injection Vial is contraindicated for use if Lidocaine is used as a solvent for intravenous injection. Lidocaine can be used as a solvent for the intramuscular route of injection for this medicine, despite contraindications.

• Calcium-containing products

  3-ZONE 250mg Injection Vial is contraindicated in neonates who are on calcium-containing intravenous solutions or infusions such as parenteral nutrition because of the risk of precipitation of 3-ZONE 250mg Injection Vial and calcium.

Warnings

• Pregnancy

  This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

• Breast-feeding

  This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Warnings

• Allergy

  This medicine is not recommended for use in patients with a known history of allergy to 3-ZONE 250mg Injection Vial or Beta-lactam Antibiotics such as penicillins and cephalosporins.

• Hemolytic anemia

  An immune mediated hemolytic anemia has been reported in patients receiving 3-ZONE 250mg Injection Vial and other cephalosporins. Report any unusual symptoms to the doctor immediately. Your doctor may advise you to discontinue the medicine if you develop hemolytic anemia until the exact cause is determined.

• Prothrombin time

  Alterations in prothrombin time (a test used to check for bleeding problems) have been reported in patients receiving 3-ZONE 250mg Injection Vial . Regular monitoring of prothrombin time may be necessary for some patients. Replacement with a suitable alternative may be required in some cases based on the clinical condition.

• Drug-resistance

  Usage of 3-ZONE 250mg Injection Vial without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

• Patients with impaired kidney or liver function

  This medicine should be used with caution in patients with kidney or liver diseases due to the increased risk of severe adverse effects. The dose of this medicine should not exceed 2 g/day for such patients.

• Clostridium difficile-associated Diarrhea

  This medicine is not recommended for use if you experience severe diarrhea after receiving 3-ZONE 250mg Injection Vial . Antibiotic therapy may cause an imbalance in the normal microbial flora in the large intestine; this may promote the growth of bacteria called Clostridium difficile, leading to severe diarrhea. Your doctor may prescribe a safer alternative based on your clinical condition.

• Use in neonates

  is not recommended in patients less than 28 days of age.

Interactions

• Amikacin Moderate
• Ethinyl Estradiol Moderate
• Cholera Vaccine Severe
• Cyclosporine Moderate

• Moderate

  This medicine may cause diarrhea, abdominal pain and blood in stools in some cases. This risk is especially higher in patients with a history of gastrointestinal diseases. Drink an adequate amount of water to prevent dehydration. Report any such symptoms to the doctor immediately. Replacement with a suitable alternative may be required based on the clinical condition.

• Moderate

  This medicine should be used with caution in patients with a history of seizure disorder or a family history of seizures since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

General Instructions

This medicine is usually administered in the hospital by a qualified healthcare professional. Carefully follow all the instructions given by your doctor. Report any unusual symptoms or side effects to the doctor immediately. Report any allergies to antibiotics to the doctor prior to using this medicine.

Other details

• Usage does not depend on food timings
• To be taken as instructed by doctor
• May cause sleepiness

How it works

3-ZONE 250mg Injection Vial works by interfering with certain processes that help the bacteria to grow and increase in number.

References

• dailymed.nlm.nih.gov - ceftriaxone- ceftriaxone sodium injection, powder, for solution [Internet] [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2dd1be9e-74cc-48e8-bf02-f34a78d80fda [cited 25 August 2019]. N/A
• Practo.com - Ceftriaxone - Uses, Dosage, Side Effects, Price, Composition | Practo [Internet]. Available from: https://www.practo.com/medicine-info/ceftriaxone-51-api [cited 25 August 2019]. 11 Jan 2018
• https://medlineplus.gov - Ceftriaxone Injection [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a685032.html [cited 25 August 2019]. 11 September 2019