Aclovir Infusion 250 mg 1 Amp

 461.00

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 250 mg
Drug Form : Infusion
Pack Size : 1 AMP
Does this requires a prescription ?Yes

Aclovir Infusion contains Acyclovir, Inf/Oral | belongs to Nucleoside analogue

SKU: pg_212_271 Categories: , ,

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    How it works

    Aclovir Infusion 250 mg 1 Amp works by inhibiting the viral DNA synthesis and replication by inhibiting the DNA polymerase enzyme.

    Side effects

    Major & minor side effects for Aclovir Infusion 250 mg 1 Amp

    • Swelling and redness at the injection site severe
    • Abdominal pain severe
    • Increased thirst severe
    • Loss of appetite severe
    • Unusual tiredness and weakness severe
    • Black or tarry stools severe
    • Fever with chills severe
    • Seizures severe
    • Unusual bleeding severe
    • Diarrhea
    • Headache

    Uses of Aclovir Infusion 250 mg 1 Amp

    What is it prescribed for?

    • Herpes Zoster Infections

      Aclovir Infusion 250 mg 1 Amp is used in the treatment of herpes zoster infection which is a viral infection caused by varicella-zoster virus.

    • Genital Herpes

      Aclovir Infusion 250 mg 1 Amp is used in the treatment of genital herpes which is a sexually transmitted viral infection caused by herpes simplex virus.

    • Chickenpox

      Aclovir Infusion 250 mg 1 Amp is used in the treatment of chicken pox which is a viral infection caused by varicella-zoster virus.

    Concerns

    Frequently asked questions

    • Onset of action

      The peak effect of this medicine can be observed in 1.5 to 2 hours after an oral dose and 2 hours after an intravenous dose.

    • Duration of Effect

      The effect of this medicine lasts for an average duration of 9 to 12 hours.

    • Safe with Alchohol?

      Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

    • Is it habit forming?

      No habit tendencies have been reported.

    • Usage in pregnancy?

      This medicine is recommended for pregnant women. Discuss with your doctor about the potential benefits and risks before deciding to take this medicine.

    • Usage while breast-feeding?

      This medicine is excreted through the breastmilk. Discuss with your doctor about the potential benefits and risks before deciding to take this medicine. Monitoring of any undesired effects is necessary.

    When not to use?

    • Allergy

      If you have a known allergy to Aclovir Infusion 250 mg 1 Amp or any other medicine belongs to the class anti-herpes virals.

    Warnings

    Warnings for special population
    • Pregnancy

      This medicine is recommended for pregnant women. Discuss with your doctor about the potential benefits and risks before deciding to take this medicine.

    • Breast-feeding

      This medicine is excreted through the breastmilk. Discuss with your doctor about the potential benefits and risks before deciding to take this medicine. Monitoring of any undesired effects is necessary.

    General Warnings
    • Hydration

      Aclovir Infusion 250 mg 1 Amp may increase the risk of kidney injury when taken with other medicines that cause kidney injury. Adequate water should be consumed to prevent the accumulation of the medicine.

    • Impaired kidney function

      Aclovir Infusion 250 mg 1 Amp is used with caution in the patients with the severe kidney injury. Suitable dose adjustments are to be made based on the clinical condition.

    • Elderly population

      Aclovir Infusion 250 mg 1 Amp is used with caution in the elderly population with kidney injury or liver injury due to increase in the risk of neurological problems. Dose adjustments are to be made based on the clinical condition.

    • Pediatric population

      The safety and efficacy of the oral formulation of Aclovir Infusion 250 mg 1 Amp has not been established in children less than 2 years of age.

    Dosage

    • Missed Dose

      Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Overdose

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Interactions

    Interaction with Medicines
    • Phenytoin moderate
    • Tacrolimus severe
    • Sulfasalazine moderate
    Disease interactions
    • severe

      Aclovir Infusion 250 mg 1 Amp should be used with caution in the patients with the pre-existing kidney injury. Inform the doctor if you experience any symptoms of sudden weight gain, changes in the frequency of urination. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.

    • moderate

      Use of high-dose intravenous Aclovir Infusion 250 mg 1 Amp may increase the risk of neurotoxicity, especially in the elderly population with a neurological disorder, kidney or liver injury. Inform the doctor if you experience any symptoms of tremors, confusion, and seizures. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.

    Lab interactions

    General Instructions

    Take Aclovir Infusion 250 mg 1 Amp with or without food. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor. Drink adequate amount of water in order to reduce the risk of kidney injury.

    Other details

    • Food timings: Information not available
    • Administration time: Information not available
    • Sleep inducing: Information not available

    References

    Additional Information>

    How to use Aclovir Infusion 250 mg 1 Amp

    Avoid rapid infusion; infuse over 1 hour to prevent renal damage; maintain adequate hydration; check for phlebitis and rotate infusion sites.
    Reconstitution: Reconstitute 500 mg with SWFI 10 mL. Do not use bacteriostatic water containing benzyl alcohol or parabens. For IV infusion dilute in D5W, D5NS, D5 1/4 NS, D5 ½ NS, LR, NS to a final concentration = 7 mg /mL.
    Compatibility: Stable in D5W, D5NS, D5 1/4 NS, D5 ½ NS, LR, NS.
    Y-site administration:
    Drug to Drug IV Compatibility: Amikacin, bumetanide, calcium gluconate, cephazolin, ceftriaxone, cimetidine, cisatracurium, dexamethasone, diphenhydramine, enalapril, famotidine, fentanyl, fluconazole, furosemide, gentamicin, heparin, hydrocortisone, hydromorphone, imipenem, insulin regular, linezolid, lorazepam, magnesium sulphate, methylprednisolone, metoclopramide, metronidazole, milrinone, nitroglycerin, propofol, ranitidine, tobramycin, vancomycin.
    Drug to Drug IV Incompatibility: Amifostine, amsacrine, aztreonam, cefepime, ciprofloxacin, dobutamine, dopamine, epinephrine, esmolol, fludarabine, foscarnet, gemcitabine, idarubicin, labetalol, levofloxacin, meropenem, midazolam, morphine, nitroprusside, ondansetron, phenylephrine, piperacillin/tazobactam, sargramostim, vinorelbine.
    When admixed: Incompatible with dobutamine, dopamine.
    Stability: Store at controlled room temperature 15°C-25°C. Reconstituted solution remains stable for 12 hours at room temperature. Do not refrigerate.

    what are the adverse effects of Aclovir Infusion 250 mg 1 Amp?

    Rash, photosensitivity, headache, dizziness, confusion, hallucinations, somnolence, convulsions. Rarely transient elevation of liver enzymes, blood urea and creatinine, acute renal failure, hepatitis, jaundice, decrease in haematological indices, pruritus, GI upset, fatigue, fever.

    What happens if I miss a dose of Aclovir Infusion 250 mg 1 Amp?

    ORAL: Herpes simplex treatment: Adults: 200 mg (400 mg in the immunocompromised or if absorption impaired) 5 times daily, usually for 5 days. Children: Under 2 yr, half adult dose; over 2 yr, same as adult dose.
    Herpes simplex, prevention of recurrence: Adults: 200 mg 4 times daily or 400 mg twice daily possibly reduced to 200 mg 2 or 3 times daily and interrupted every 6-12 mth.
    Herpes simplex, prophylaxis in the immunocompromised: Adults: 200-400 mg 4 times daily. Children: Under 2 yr, half adult dose; over 2 yr, same as adult dose.
    Varicella and herpes zoster, treatment: Adults: 800 mg 5 times daily for 7 days. Children: Varicella: 20 mg/kg (max 800 mg) 4 times daily for 5 days or under 2 yr, 200 mg 4 times daily; 2-5 yr, 400 mg 4 times daily; over 6 yr, 800 mg 4 times daily.
    IV INFUSION: Infusion over 1 hr.
    Herpes simplex or recurrent varicella-zoster: Adults: 5 mg/kg every 8 hr; doubled in primary and recurrent varicella-zoster in the immunocompromised and in simplex encephalitis (for which it should be continued for at least 10 days). Children: Up to 3 mth, 10 mg/kg every 8 hr; 3 mth-12 yr, 250 mg/m² every 8 hr, dose doubled in the immunocompromised and in simplex encephalitis (for which it should be continued for at least 10 days).
    Encephalitis: Adults & Children: =12 yr: 10 mg/kg IV every 8 hr for 10 days. lt;12 yr: 20 mg/kg IV every 8 hr for 10 days.

    One of the following licensed pharmacy from the nearest location will deliver Aclovir Infusion 250 mg 1 Amp. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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