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Acuvil tablet 500 mg 10's

Belongs to Category,

Acuvil tablet contains Levofloxacin, Inf/Oral | belongs to Quinolone

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How it works

Acuvil tablet 500 mg 10’s works by inhibiting an enzyme required for the bacterial DNA to replicate, thus inhibiting bacterial cell division.

Side effects

Major & minor side effects for Acuvil tablet 500 mg 10’s

  • Diarrhea severe
  • Abdominal pain severe
  • Confusion severe
  • Fever severe
  • Redness of skin severe
  • Change in taste
  • Constipation
  • Dizziness
  • Headache
  • Nausea or vomiting

Uses of Acuvil tablet 500 mg 10’s

What is it prescribed for?

  • Cystitis

    Acuvil tablet 500 mg 10’s is used in the treatment of Cystitis which is a bladder infection caused by E.coli, Pseudomonas aeruginosa, Enterococci, and Klebsiella pneumoniae.

  • Pyelonephriits

    Acuvil tablet 500 mg 10’s is used in the treatment of Pyelonephritis which is a type of kidney infection caused by E.coli, Pseudomonas aeruginosa, Enterococci, and Klebsiella pneumoniae.

  • Nongonococcal Urethritis

    Acuvil tablet 500 mg 10’s is used in the treatment of Nongonococcal Urethritis which is an inflammation of urethra caused by E.coli, Pseudomonas aeruginosa, and Klebsiella.

  • Skin and structure Infection

    Acuvil tablet 500 mg 10’s is used in the treatment of Skin and Structure infection like cellulitis, wound infection, and cutaneous abscess caused by Streptococcus pyogenes and Staphylococcus aureus.

  • Pneumonia

    Acuvil tablet 500 mg 10’s is used in the treatment of community-acquired pneumonia which is a most common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.

  • Bronchitis

    Acuvil tablet 500 mg 10’s is used in the treatment of bronchitis which is an inflammation of the lungs caused by Streptococcus pneumoniae, Haemophilus influenzae, and some Mycoplasma pneumoniae.

  • Inhalation Anthrax

    Acuvil tablet 500 mg 10’s is used in the treatment of anthrax which is a rare but serious bacterial illness caused by Bacillus anthracis.

  • Plague

    Acuvil tablet 500 mg 10’s is used in the treatment of anthrax which is a rare but serious bacterial illness caused by Bacillus anthracis.

Concerns

Frequently asked questions

  • Onset of action

    The peak effect of this medicine can be observed within 1 to 2 hours of administration of the dose.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 24 to 32 hours.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Usage in pregnancy?

    This medicine is generally not recommended for use in pregnant women unless absolutely necessary and only under the supervision of a doctor.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary since it may affect the development of the infant's joints. Use only if clearly needed and only under the supervision of a doctor. Close monitoring of the infant for any undesired effects like diarrhoea, diaper rash, etc., is necessary for such cases. Avoid breastfeeding for 4 to 6 hours after a dose to decrease the exposure of the infant to the Acuvil tablet 500 mg 10’s in breast milk.

When not to use?

  • Allergy

    This medicine is not recommended for use if you have a known allergy to Acuvil tablet 500 mg 10’s or any other fluoroquinolones.

  • Tendinitis or tendon rupture

    This medicine is not recommended for use if you have a past history of tendinitis or tendon rupture after using Acuvil tablet 500 mg 10’s or any other fluoroquinolones.

  • Myasthenia gravis

    This medicine is not recommended for use if you have a past history of myasthenia gravis or family history of myasthenia gravis (weakness and rapid tiring of muscles which are under voluntary control).

Warnings

Warnings for special population
  • Pregnancy

    This medicine is generally not recommended for use in pregnant women unless absolutely necessary and only under the supervision of a doctor.

  • Breast-feeding

    This medicine is generally not recommended for use in pregnant women unless absolutely necessary and only under the supervision of a doctor.

Warnings

Warnings for special population
  • Tendinitis and Tendon ruputure

    Use of Acuvil tablet 500 mg 10’s will increase the risk to develop tendinitis or tendon rupture during the treatment or several months after treatment. This may affect your shoulders, hands, ankles, or other parts of your body. You are at a higher risk if you are more than 60 years of age or if you have undergone a transplant of kidney, heart, or lung. You are also at a higher risk if you are on corticosteroids like dexamethasone, methylprednisolone, or prednisone.

  • Drug-resistance

    Usage of Acuvil tablet 500 mg 10’s without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

  • Alternative treatment

    Acuvil tablet 500 mg 10’s can be used to treat acute bacterial exacerbation of chronic bronchitis or uncomplicated cystitis, but only as a last resort. This drug should be used only if you have no alternative treatment options for the above-mentioned conditions.

Dosage

  • Missed Dose

    The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already the time for your next scheduled dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

Interaction with Medicines
  • Escitalopram severe
  • Ethinyl Estradiol moderate
  • Corticosteroids severe
  • Quinidine severe
  • Aspirin moderate
  • Antidiabetic drugs moderate
Disease interactions
  • severe

    This medicine should be used with extreme caution in patients with a history of seizure disorder and other central nervous system abnormalities. Report any incidence of tremors, restlessness, anxiety, confusion, hallucinations, etc., to the doctor on priority. It is advisable to avoid using caffeine-containing products while on therapy with fluoroquinolones.

  • severe

    This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis. Inform your doctor if you have any history of gastrointestinal diseases. Report any incidence of severe diarrhoea, abdominal pain, and blood in stools to the doctor immediately.

  • severe

    This medicine should be used with extreme caution in patients with a history of heart diseases and electrolyte disturbances, especially elderly patients. Report any incidence of discomfort in the chest, heart palpitations, etc., to the doctor on priority. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.

General Instructions

Take Acuvil tablet 500 mg 10’s with or without food. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking Acuvil tablet 500 mg 10’s before completion of the course.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • Does not cause sleepiness

References

How to use Acuvil tablet 500 mg 10’s

IV: Infuse IV solution over 60 min. Too rapid infusion can lead to hypotension. Avoid administration through an intravenous line with a solution containing multivalent cations (i.e., magnesium, calcium).
Compatibility: Stable in D5LR, D5NS, D5W, NS; incompatible with mannitol 20%, sodium bicarbonate 5%.
Y-site administration:
Drug to Drug IV Compatibility: Amikacin, aztreonam, bumetanide, calcium gluconate, cefepime, ceftriaxone, cimetidine, dexamethasone, diltiazem, diphenhydramine, dobutamine, dopamine, enalapril, epinephrine, esmolol, famotidine, fentanyl, fluconazole, gentamicin, hydrocortisone, hydromorphone, imipenem, labetalol, linezolid, magnesium sulphate, methylprednisolone, metoclopramide, metronidazole, midazolam, morphine, ondansetron, phenylephrine, tobramycin, vancomycin.
Drug to Drug IV Incompatibility: Acyclovir, alprostadil, amiodarone, azithromycin, cephazolin, furosemide, heparin, indomethacin, insulin regular, lansoprazole, nitroglycerin, sodium nitroprusside, pantoprazole, piperacillin/tazobactam, propofol, ranitidine.
Stability: Stable for 72 hours when diluted to 5 mg/mL in a compatible IV fluid. Store at room temperature. Stable for 14 days when stored under refrigeration. Stable for 6 months when frozen. Do not refreeze.

what are the adverse effects of Acuvil tablet 500 mg 10’s

GI upset, raised liver enzymes, tendon disorders (discontinue), insomnia, headache, dizziness, anorexia, dysgeusia, dyspnoea, arthralgia, myalgia, tinnitus, asthenia, pyrexia, reports of visual disturbances, hepatic injury, severe skin disorders, peripheral neuropathy (discontinue).

What is the dose of Acuvil tablet 500 mg 10’s

Lower Respiratory Infection: Adults: 500 mg orally or IV once daily for 7-14 days or 750 mg orally or IV once daily for 5 days.
Nosocomial Pneumonia: Adults: 750 mg orally or IV once daily for 7-14 days.
Upper Respiratory Infection: Sinusitis: Adults: 500 mg orally or IV once daily for 10-14 days or 750 mg orally or IV once daily for 5 days.
Skin Infection: Adults: Uncomplicated: 500 mg orally or IV once daily for 7-10 days. Complicated: 750 mg orally or IV once daily for 7-14 days.
Urinary Tract Infection: Adults: Complicated UTI/Acute Pyelonephritis: 250 mg orally or IV once daily for 10 days. Uncomplicated UTI: 250 mg orally or IV once daily for 3 days. Chronic Bacterial Prostatitis: 500 mg orally or IV once daily for 28 days.
Children: Not recommended.

One of the following licensed pharmacy from the nearest location will deliver Acuvil tablet 500 mg 10’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

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