Adrenaline Injection 1 mg/mL 100 Ampx1 mL PDH Labs

 250.00

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 1 mg/mL
Drug Form : Injection
Pack Size : 100 Ampx1 mL
Does this requires a prescription ?Yes

Adrenaline Injection contains Adrenaline, Inj | belongs to Beta-2 agonist

SKU: pg_452_443 Categories: ,

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    How to use Adrenaline Injection 1 mg/mL 100 Ampx1 mL PDH Labs

    Central administration only; IV infusions require an infusion pump. Endotracheal: Doses (2-2.5 times the IV dose) should be diluted to 10 mL with NS or distilled water.
    IM: Intramuscularly into anterolateral aspect of thigh. SC: Use only 1:1000 solution. Continuous IV Infusion:
    Rate of infusion (mL/hr) = dose (mcg/kg/min) x weight (kg) x 60 min/hr divided by the concentration (mcg/min). Max concentration: 64 mcg/ min. Direct IV or Intraosseous: Dilute to a max Concentration of 100 mcg/ mL (if using 1:10000 concentration, no dilution is necessary).
    Compatibility: Stable in dextran 6% in dextrose, dextran 6% in NS, D5LR, D5 1/4NS, D5 1/2NS, D5 NS, D5W, D10W, D10 NS, LR, NS. Incompatible with sodium bicarbonate 5%, alkalies or oxidizing agents including bromine, chlorine, chromates, iodine, metal salts (as from iron), nitrites, oxygen and permanganates.
    Y-site administration:
    Drug to Drug IV Compatibility: Amikacin, amiodarone, aztreonam, bumetanide, calcium gluconate, cephazolin, ceftriaxone, cimetidine, cisatracurium, dexamethasone, diltiazem, diphenhydramine, dobutamine, dopamine, enalapril, esmolol, famotidine, fentanyl, fluconazole, furosemide, gentamicin, heparin, hydrocortisone, hydromorphone, imipenem, labetalol, levofloxacin, linezolid, lorazepam, magnesium sulphate, methylprednisolone, metoclopramide, midazolam, milrinone, morphine, nitroglycerin, nitroprusside, norepinephrine, ondansetron, phenylephrine, piperacillin/tazobactam, propofol, ranitidine, tobramycin, vancomycin, vasopressin, vecuronium.
    Drug to Drug IV Incompatibility: Acyclovir, ampicillin, thiopental.
    When admixed: Incompatible with aminophylline, hyaluronidase, mephentermine, sodium bicarbonate.

    what are the adverse effects of Adrenaline Injection 1 mg/mL 100 Ampx1 mL PDH Labs?

    Anxiety, tremor, tachycardia, headache, cold extremities, arrhythmias, cerebral haemorrhage, pulmonary oedema, nausea, vomiting, sweating, weakness, dizziness and hyperglycaemia.

    What happens if I miss a dose of Adrenaline Injection 1 mg/mL 100 Ampx1 mL PDH Labs?

    Adults: Asystole/pulseless arrest, pulseless ventricular tachycardia/ventricular fibrillation: IV or IO: 1 mg every 3-5 minutes until return of spontaneous circulation; if this approach fails, higher doses of epinephrine (up to 0.2 mg/kg) have been used for treatment of specific problems (e.g. beta-blocker or calcium channel blocker overdose). Endotracheal: 2-2.5 mg every 3-5 minutes until IV/IO access established or return of spontaneous circulation; dilute in 5-10 mL NS or sterile water.
    Bradycardia (symptomatic; unresponsive to atropine or pacing): IV infusion: 2-10 mcg/minute or 0.1-0.5 mcg/kg/minute (7-35 mcg/minute in a 70 kg patient); titrate to desired effect.
    Bronchodilator: SC: 0.3-0.5 mg (1:1000 [1 mg/mL] solution) every 20 minutes for 3 doses.
    Hypersensitivity reaction: SC administration results in slower absorption and is less reliable. IM administration in the anterolateral aspect of the middle third of the thigh is preferred in the setting of anaphylaxis. IM or SC: 0.2-0.5 mg (1:1000 [1 mg/mL] solution) every 5-15 minutes in the absence of clinical improvement. If seems appropriate, the 5 minute interval between injections may be shortened to allow for more frequent administration. IV: 0.1 mg (1:10,000 [0.1 mg/mL] solution) over 5 minutes; may infuse at 1-4 mcg/minute to prevent the need to repeat injections frequently or may initiate with an infusion at 5-15 mcg/minute (with crystalloid administration). In general, IV administration should only be done in patients who are profoundly hypotensive or are in cardiopulmonary arrest refractory to volume resuscitation and several epinephrine injections.
    Self-administration following severe allergic reactions (e.g. insect stings, food): The World Health Organization recommend the availability of one dose for every 10-20 minutes of travel time to a medical emergency facility. More than 2 doses should only be administered under direct medical supervision.
    Hypotension/shock, severe and fluid resistant (unlabeled use): IV infusion: Initial: 0.1-0.5 mcg/kg/minute (7-35 mcg/minute in a 70 kg patient); titrate to desired response.
    Infants and Children: Asystole/pulseless arrest, pulse less ventricular tachycardia/ ventricular fibrillation (after failed defibrillation attempts): IV or IO: 0.01 mg/kg (0.1 mL/kg of 1:10,000 [0.1 mg/mL] solution) (max 1 mg/dose) every 3-5 minutes until return of spontaneous circulation. Endotracheal: 0.1 mg/kg (0.1 mL/kg of 1:1000 [1 mg/mL] solution) (max 2.5 mg/dose) every 3-5 minutes until IV/IO access established or return of spontaneous circulation. Flush with 5 mL of NS immediately after administration.
    Postresuscitation infusion to maintain cardiac output or stabilize: IV or IO: 0.1-1 mcg/kg/minute; doses lt;0.3 mcg/kg/minute generally produce beta-adrenergic effects and higher doses ( gt;0.3 mcg/kg/minute) generally produce alpha-adrenergic vasoconstriction; titrate dosage to desired effect.
    Bradycardia (symptomatic; unresponsive to atropine or pacing): IV or IO: 0.01 mg/kg (0.1 mL/kg of 1:10,000 [0.1 mg/mL] solution) (max 1 mg/dose) every 3-5 minutes as needed.
    Endotracheal: 0.1 mg/kg or (0.1 mL/kg of 1:1000 [1 mg/mL] solution) (max 2.5 mg/dose) every 3-5 minutes as needed until IV/lO access established. Flush with 5 mL of NS immediately after administration. Continuous infusion: IV/IO: 0.1-1 mcg/kg/minute; doses lt;0.3 mcg/kg/minute generally produce beta- adrenergic effects and higher doses ( gt;0.3 mcg/kg/ minute) generally produce alpha-adrenergic vasoconstriction; titrate dosage to desired effect.
    Bronchodilator: SC: 0.01 mg/kg (0.01 mL/kg of 1:1000 [1 mg/mL] solution); max 0.5 mg/dose) every 20 minutes for 3 doses.
    Hypersensitivity reaction: IM/SC: 0.01 mg/kg (0.01 mL/kg of 1:1000 [1 mg/mL] solution), max 0.3 mg/dose, every 5-15 minutes; larger IM or SC doses, use of IV route, or continuous infusion may be needed for severe anaphylactic reactions. If appropriate, the 5 minute interval between injections may be shortened to allow for more frequent administration.
    Hypotension/shock, fluid-resistant (unlabeled use): Continuous IV infusion: 0.1-1 mcg/kg/minute; doses up to 5 mcg/kg/minute may rarely be necessary.

    One of the following licensed pharmacy from the nearest location will deliver Adrenaline Injection 1 mg/mL 100 Ampx1 mL PDH Labs. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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