240.00

Content Details
Information on this page was last modified on : 2019/08/10 5:45:25 PM
, This drug requires a valid prescription from PMDC registered health practitioner.
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Contains

Afoxin tablet contains Clarithromycin | belongs to Macrolide

Product SKUpg_507_536
Drug Strength
Pack size

Side effects

Major & minor side effects for Afoxin tablet 250 mg 10’s

  • Fever or chills severe
  • Lower back pain severe
  • Abdominal pain severe
  • Nausea or Vomiting severe
  • Diarrhea severe
  • Skin Rash severe
  • Acid or sour stomach
  • Excessive air or gas in stomach
  • Headache
  • Heartburn

Uses of Afoxin tablet 250 mg 10’s

What is it prescribed for?

  • Tonsilitis/Pharyngitis

    Afoxin tablet 250 mg 10’s is used in the treatment of Tonsilitis/Pharyngitis caused by Streptococcus pneumoniae, Haemophillus influenzae and some fungal infections.

  • Bronchitis

    Afoxin tablet 250 mg 10’s is used in the treatment of Bronchitis which is an inflammation in lungs caused by Streptococcus pneumoniae, Haemophilus influenzae, and some Mycoplasma pneumoniae.

  • Pneumonia

    Afoxin tablet 250 mg 10’s is used in the treatment of Pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.

  • Helicobacter pylori Infection

    Afoxin tablet 250 mg 10’s is used in the treatment of the infection of the stomach characterized by ulcers. It is caused by helicobacter pylori bacteria.

  • Skin and Structure Infection

    Afoxin tablet 250 mg 10’s is used to treat skin and structure infections caused by Staphylococcus aureus and Streptococcus pyogenes.

Concerns

Frequently asked questions

  • Onset of action

    The peak effect of this medicine can be observed in 2 to 3 hours for an immediate release tablet and 5 to 8 hours for an extended release tablet.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 9 to 21 hours for an Immediate release.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendency has been reported.

  • Usage in pregnancy?

    This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

  • Usage while breast-feeding?

    This medicine is not recommended for breastfeeding women unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine. Monitoring of undesired effects like diarrhea, candidiasis (thrush, diaper rash) is necessary.

When not to use?

  • Allergy

    Avoid taking this medicine if you have a known allergy to it or any other macrolides.

  • Impaired Liver function

    Afoxin tablet 250 mg 10’s is not recommended in the patients with the history of any liver injury.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

  • Breast-feeding

    This medicine is not recommended for breastfeeding women unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine. Monitoring of undesired effects like diarrhea, candidiasis (thrush, diaper rash) is necessary.

Warnings

Warnings for special population
  • Impaired liver function

    Afoxin tablet 250 mg 10’s is not recommended in the patients with the history of liver injury. Any signs and symptoms of liver injury like elevated liver enzymes and yellow colored eyes and skin should be reported to the doctor. Discontinue the medicine if the symptoms persist.

  • QT prolongation

    Afoxin tablet 250 mg 10’s should be used with caution in the patients receiving QT prolongation medications as it can increase the risk of arrhythmia. Frequent monitoring of heart function is necessary and an alternate medicine should be considered.

  • Drug-resistance

    Afoxin tablet 250 mg 10’s without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

  • Allergy

    Avoid taking this medicine if you have a known allergy to Afoxin tablet 250 mg 10’s or other macrolides. Seek immediate medical attention if the patient experiences any allergic symptoms like rashes, itching, nausea, vomiting, swelling of lips, hands, and feet.

  • Impaired kidney function

    Afoxin tablet 250 mg 10’s should be used with caution in the patients with kidney injury. Half of the recommended dose should be administered if the CrCl is less than 30 ml/min.

Dosage

  • Missed Dose

    The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

Interaction with Medicines
  • Clonazepam Moderate
  • Amiodarone severe
  • Ethinyl Estradiol Moderate
  • Atorvastatin severe
Disease interactions
  • severe

    Inform your doctor if you have arrhythmia, any heart disease or drugs that prolong QT interval such as psychiatric drugs and anti-arrhythmic drugs.

  • Moderate

    Avoid taking Afoxin tablet 250 mg 10’s if you experience severe diarrhea, abdominal pain, and blood in stools after taking the medicine. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.

General Instructions

Afoxin tablet 250 mg 10’s Take Esomeprazole as instructed by the doctor. This medicine should be taken an hour before food. An adequate amount of water should be consumed with this medicine. Do not take this medicine for longer than the recommended duration.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • May cause sleepiness

How it works

[Ppost_tital] works by stopping the growth of the bacteria by interfering with the bacterial protein synthesis.

References

How to use Afoxin tablet 250 mg 10’s

For IV administration only. 500 mg should be administered into one of the larger proximal veins as an IV infusion over 60 mins, using a solution concentration of about 2 mg/mL. Clarithromycin should not be given as a bolus or an IM injection.

what are the adverse effects of Afoxin tablet 250 mg 10’s

GI upset, paraesthesia, stomatitis, glossitis, oral monilia, tongue or tooth discolouration, headache, arthralgia, myalgia, rash, transient CNS effects, allergic reactions, hepatic dysfunction, reversible hearing loss. Rarely, pseudomembranous colitis, hypoglycaemia, leucopenia, thrombocytopenia, renal dysfunction, QT prolongation, vasodilation, hyperhidrosis, insomnia, headache, dysgeusia, C.difficile associated diarrhoea.

What is the dose of Afoxin tablet 250 mg 10’s

ORAL: Adults: 500 mg once daily or 250 mg twice daily with food for 7 to 14 days. Severe infections, 500 mg twice daily. Children: All twice daily. Under 1 yr, 7.5 mg/kg; 1-2 yr, 2.5 mL (62.5 mg); 3-6 yr, 5 mL (125 mg); 7-9 yr, 7.5 mL (187.5 mg); 10-12 yr, 10 mL (250 mg).
Lower Respiratory Tract Infections: Adults: 250-500 mg every 12 hr for 7-14 days. Children:gt; 6 mth: 7.5 mg/kg every 12 hr for 10 days.
Upper Respiratory Tract Infections: Adults: Pharyngitis/Tonsillitis: 250 mg every 12 hr for 10 days.
Sinusitis: 500 mg every 12 hr for 14 days. Children: gt; 6 mth: Pharyngitis/Tonsillitis/Sinusitis: 7.5 mg/kg every 12 hr for 10 days.
INJECTION: Adults & Children: Over 12 yr: By IV, 500 mg twice daily.
Mycobacterium Avium Complex: Prevention & Treatment: Adults: 1000 mg twice daily. Children: gt;20 mth: 7.5 mg/kg every 12 hr. Max: 500 mg every 12 hr.
Otitis Media: Children: gt;6 mth: 7.5 mg/kg every 12 hr for 10 days.
Skin Infection: Adults: 250 mg every 12 hr for 7-14 days. Children: gt;6 mth: 7.5 mg/kg every 12 hr for 10 days.

One of the following licensed pharmacy from the nearest location will deliver Afoxin tablet 250 mg 10’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

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