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Information on this page was last modified on : 2021/04/20 3:09:09 PM

Alimta Injection 100 mg 1 Vial

Belongs to Category,

Alimta Injection contains Pemetrexed | belongs to Antimetabolite

Alternate brands of Alimta Injection 100 mg 1 Vial

Brand Name Price Savings
Alimta Injection 500 mg 1 Vial  70,000.00 You will pay -51100 more
List of alternate brands

How it works

Alimta Injection 100 mg 1 Vial works by blocking the action of a certain substance in the body that may help cancer cells multiply.

Side effects

Major & minor side effects for Alimta Injection 100 mg 1 Vial

  • Low WBC and Platelet count severe
  • Fever and chills severe
  • Mouth ulcers severe
  • Nausea and Vomiting severe
  • Skin rash severe
  • Decreased urine output severe
  • Blood in urine and stools severe
  • Diarrhea
  • Cough
  • Hair loss
  • Change in mood

Uses of Alimta Injection 100 mg 1 Vial

What is it prescribed for?

  • Malignant Pleural Mesothelioma

    This medicine is used in the treatment of cancer that develops in the thin layer of tissue surrounding the lungs (Pleura).

  • Non-Small Cell Lung Cancer

    This medicine is used in the treatment of cancer that affects the lungs.

Concerns

Frequently asked questions

  • Onset of action

    The peak effect of this medicine can be observed immediately after intravenous injection.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 6 to 9 hours.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendency has reported.

  • Usage in pregnancy?

    This medicine is not recommended for pregnant women.

  • Usage while breast-feeding?

    This medicine is not recommended in breastfeeding women.

When not to use?

  • Allergy

    Not recommended in patients with known allergy to Alimta Injection 100 mg 1 Vial .

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for pregnant women.

  • Breast-feeding

    This medicine is not recommended in breastfeeding women.

General Warnings
  • Premedication

    Before starting the treatment, premedication with oral folic acid and intramuscular vitamin B12 is recommended to reduce the severity of hematologic and gastrointestinal toxicity.

  • Blood cell count

    This medicine is known to decrease the neutrophils and platelets count. Blood reports should be obtained before initiating the treatment. The dose of this medicine should be reduced based on the absolute neutrophil count and platelet count.

  • Skin reactions

    This medicine may cause severe skin reactions. To reduce the severity of these reactions, corticosteroids like dexamethasone should be given before, during and after [post-title] administration.

  • Infections

    The patients receiving this medicine have a higher chance of developing infections. Hold the chemotherapy and start with broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.

Dosage

  • Missed Dose

    It is advised not to miss any dose. If you miss any dose, you should contact your doctor immediately.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

Interaction with Medicines
  • Clozapine severe
  • Live attenuated vaccines and related products severe
  • Fluoroquinolone antibiotics moderate
Disease interactions
  • moderate

    This medicine should be used with caution in patients with the kidney disease. Close monitoring of kidney function is necessary. It is not recommended in patients with Creatinine Clearance less than 45 ml/min.

General Instructions

This medicine should be used with caution in patients with the kidney disease. Close monitoring of kidney function is necessary. It is not recommended in patients with Creatinine Clearance less than 45 ml/min.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • Does not cause sleepiness

References

Additional Information:

How to use Alimta Injection 100 mg 1 Vial

Administered as an IV infusion over 10 min. Pemetrexed is compatible with standard polyvinyl chloride (PVC) administration sets and IV solution bags.
Reconstitution: Reconstitute each 100 mg vial with 4.2 mL of 0.9% NaCl (preservative free). Reconstitute 500 mg vials with 20 mL of 0.9% NaCl (preservative free). Reconstitution of either size vial gives a solution containing pemetrexed 25 mg/mL. Gently swirl each vial until the powder is completely dissolved. Further dilution is required. An appropriate quantity of the reconstituted pemetrexed solution must be further diluted into a solution of 0.9% NaCl (preservative free), so that the total volume of solution is 100 mL.
Compatibility: Stable in NS. Incompatible with diluents containing calcium, including Ringer’s lactate injection and Ringer’s injection.
Stability: Store at 25°C (77°F); excursions are permitted between 15°C-30°C (59°F-86°F). Reconstituted and infusion solutions are stable for up to 24 hours following initial reconstitution when stored refrigerated between 2°C-8°C (36°F-46°F) or at 25°C (77°F); excursions are permitted to 15°C-30°C (59°F-86°F). Discard unused portion.

what are the adverse effects of Alimta Injection 100 mg 1 Vial?

Blood dyscrasias, conjunctivitis, GI upset, dehydration, fatigue, neuropathy, skin reactions, alopecia, pyrexia, renal failure, chest pain, allergic reactions.

What happens if I miss a dose of Alimta Injection 100 mg 1 Vial?

Malignant Pleural Mesothelioma: Adults: 500 mg/m² IV over 10 min on Day 1 of each 21-day cycle with cisplatin 75 mg/m² infused over 2 hr beginning 30 min after pemetrexed.

One of the following licensed pharmacy from the nearest location will deliver Alimta Injection 100 mg 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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