Allopurinol 100mg Tablet

How it Works

Allopurinol is a medication used primarily to treat gout and certain types of kidney stones. It works by reducing the production of uric acid in the body. Allopurinol inhibits the enzyme xanthine oxidase, which is responsible for converting hypoxanthine and xanthine into uric acid. By decreasing the amount of uric acid produced, allopurinol helps prevent gout attacks and reduces the formation of uric acid crystals that can lead to kidney stones and joint damage.

Side Effects

• Rash
• Nausea
• Diarrhea
• Abdominal pain
• Elevated liver enzymes
• Acute gout attacks upon initiation
• Headache
• Drowsiness
• Hypersensitivity reactions (e.g., Stevens-Johnson syndrome)

Indications

• Chronic gout
• Recurrent calcium oxalate kidney stones
• Hyperuricemia associated with cancer chemotherapy
• Secondary hyperuricemia due to certain metabolic disorders

Contraindications

• Hypersensitivity to allopurinol or any of its components
• Acute gout attack (should not be initiated during an acute attack)
• Severe renal impairment without appropriate dose adjustment
• Severe hepatic impairment
• Pregnancy and lactation (use with caution)

Price Comparison in Different Countries

Top 5 Global Brands

1. Zyloprim (Aloprim) – Hikma Pharmaceuticals
2. Allosig – Aspen Pharmacare
3. Puricos – Mylan
4. Progout – Sanofi
5. Milurit – Teva Pharmaceuticals