Alosita-Met tablet 50/500 mg 2×7’s
Alosita-Met tablet contains Sitagliptin and Metformin | belongs to Biguanide/Dipeptidyl peptidase-4 inhibitor
Alternate brands of Alosita-Met tablet 50/500 mg 2×7’s
|Treviamet XR tablet 50/1000 mg 14’s||₨ 433.00||You will pay -125 more|
|Treviamet XR tablet 50/500 mg 14’s||₨ 440.00||You will pay -132 more|
|Treviamet XR tablet 50/850 mg 14’s||₨ 336.00||You will pay -28 more|
|Treviamet tablet 50/1000 mg 14’s||₨ 440.00||You will pay -132 more|
|Treviamet tablet 50/500 mg 14’s||₨ 394.94||You will pay -86.94 more|
How it works
Alosita-Met tablet 50/500 mg 2×7’s works to competitively inhibit the enzyme dipeptidyl peptidase 4 (DPP-4). This enzyme breaks down the incretins GLP-1 and GIP, gastrointestinal hormones released in response to a meal. By preventing breakdown of GLP-1 and GIP, they are able to increase the secretion of insulin and suppress the release of glucagon by the alpha cells of the pancreas. This drives blood glucose levels towards normal. As the blood glucose level approaches normal, the amounts of insulin released and glucagon suppressed diminishes, thus tending to prevent an "overshoot" and subsequent low blood sugar (hypoglycemia), which is seen with some other oral hypoglycemic agents.
Frequently asked questions
Onset of action
Duration of Effect
Safe with Alchohol?
Is it habit forming?
Usage in pregnancy?
Usage while breast-feeding?
- drugs.com - Metformin and sitagliptin [Internet]. Available from: https://www.drugs.com/mtm/metformin-and-sitagliptin.html [cited 30/6/2020]. 9/4/2020
- wikipedia - Mechanism of action [Internet]. Available from: https://en.wikipedia.org/wiki/Sitagliptin#Mechanism_of_action [cited 30/6/2020]. 19/6/2020
what are the adverse effects of Alosita-Met tablet 50/500 mg 2×7’s?
Metformin: GI upset, taste disturbance, rarely lactic acidosis, abnormal liver function tests, hepatitis, skin reactions, reduced B12 absorptions.
Sitagliptin: Reports of pancreatitis and serious hypersensitivity reactions, including anaphylaxis and Stevens-Johnson syndrome. Hypoglycaemia, headache, bullous pemphigoid. Monotherapy: Osteoarthritis, pain in extremity, upper RTI. With metformin: GI upset. With a glitazone: Flatulence, peripheral oedema. With insulin: Influenza.
What happens if I miss a dose of Alosita-Met tablet 50/500 mg 2×7’s?
Adults: Initially, 50 mg/500 mg or 50 mg/1000 mg twice daily based on dose of metformin already being taken. For patients receiving components as separate tab, switch to equivalent dose. Doses of sulfonylurea or insulin may need to be reduced. Max daily dose of sitagliptin, 100 mg. Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Alosita-Met tablet 50/500 mg 2×7’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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