₨ 9,500.00
MBBS
Arixtra Injection 7.5 mg 10 Pre filled Syringex.6 mL
- Does this requires a prescription ? Yes
- Generic Name: Fondaparinux Sodium
- Drug Strength : 7.5 mg
- Drug Form : Injection
- Pack Size : 10 Pre filled Syringex.6 mL
- Product SKU : pg_1575_2052
Arixtra Injection contains Fondaparinux Sodium | belongs to Pentasaccharide that inhibits activated factor X
Alternate brands of Arixtra Injection 7.5 mg 10 Pre filled Syringex.6 mL
| Brand Name | Price | Savings |
|---|---|---|
| Arixtra Injection 7.5 mg 7 Pre filled Syringex.6 mL | ₨ 7,000.00 | You can save 2500 |
| Arixtra Injection 2.5 mg 10 Pre filled Syringex.5 mL | ₨ 4,350.00 | You can save 5150 |
How it works
Arixtra Injection 7.5 mg 10 Pre filled Syringex.6 mL works by blocking certain substances called clotting factors that help in the clotting of blood.
Side effects
Major & minor side effects for Arixtra Injection 7.5 mg 10 Pre filled Syringex.6 mL
- Pale skin
- Trouble breathing
- Unusual bleeding or bruising
- Unusual tiredness or weakness
- Fever
- Nausea or Vomiting
- Bleeding gums
- Dizziness
- Sore throat
- Dry mouth
Uses of Arixtra Injection 7.5 mg 10 Pre filled Syringex.6 mL
What is it prescribed for?
-
Deep Vein Thrombosis Prophylaxis and Treatment after surgery
This medicine is used to treat and prevent the formation of blood clots in veins following hip fracture, hip replacement, knee replacement surgery, abdominal surgery, etc.
-
Deep Vein Thrombosis
This medicine is used for the prevention and treatment of blood clot formation in a deep vein, most commonly in the legs.
-
Pulmonary Embolism
This medicine is used for the treatment and prevention of pulmonary embolism, a condition where one or more arteries in the lungs become blocked by a clot. The blood clot is normally formed elsewhere and migrates to the lung via blood.
-
Acute Coronary Syndrome
This medicine is used for the treatment of acute coronary syndrome (sudden or reduce blood flow to the heart) with or without ST-segment elevation or unstable angina.
Concerns
Frequently asked questions
-
Onset of action
The peak effect of this medicine can be observed within 2-3 hours of administration of the dose.
-
Duration of Effect
The amount of time for which this medicine remains effective in the body is not clinically established.
-
Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
-
Is it habit forming?
No habit-forming tendencies were reported.
-
Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
-
Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
When not to use?
-
Allergy
This medicine is not recommended for use in patients with a known allergy to Arixtra Injection 7.5 mg 10 Pre filled Syringex.6 mL or any other inactive ingredients present along with it.
-
Active major bleeding
This medicine is not recommended for use in patients having major active bleeding due to the increased risk of worsening of the patient's condition.
-
Bacterial endocarditis
This medicine is not recommended for use in patients with bacterial endocarditis due to the increased risk of worsening of the patient's condition.
-
Severe renal impairment
This medicine is not recommended for use in patients with severe renal impairment (creatinine clearance < 30 ml/min) due to the increased risk of worsening of the patient's condition.
Warnings
-
Pregnancy
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
-
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
-
Subcutaneous use only
This medicine is intended for subcutaneous use only. Do not administer intramuscularly.
-
Bleeding
This medicine is known to cause severe bleeding. It is not recommended for patients with conditions like gastrointestinal bleeding, head injury, and patients who are about to undergo surgery. Any symptoms of blood in the stools, vomiting blood, or blood in the urine should be reported to the doctor on priority. Close monitoring of prothrombin time is necessary while receiving this medicine.
-
Other medicines
Concomitant administration of this medicine and other anticoagulants may enhance the risk of bleeding. These agents include desirudin, fibrinolytic agents, GP IIb/IIIa receptor antagonists, heparin, heparinoids, or Low Molecular Weight Heparin (LMWH). Other antiplatelet medicinal products (acetylsalicylic acid, dipyridamole, sulfinpyrazone, ticlopidine or clopidogrel), and NSAIDs should be used with caution. Close monitoring is necessary if coadministered.
-
Spinal or epidural Anesthesia and Post-operative Indwelling Epidural catheter use
Use of this medicine with spinal or epidural anesthesia or spinal puncture may result in spinal or epidural hematomas, which may result in long-term or permanent paralysis. The risk of these events may be higher with post-operative use of indwelling epidural catheters or concomitant use of other drugs affecting hemostasis such as NSAIDs. Monitor patients undergoing these procedures for signs and symptoms of neurologic impairment such as midline back pain, sensory and motor deficits (numbness, tingling, or weakness in lower limbs), and bowel or bladder dysfunction. Consider the potential risks and benefits before neuraxial intervention in patients anticoagulated or who may be anticoagulated for thromboprophylaxis.
-
Low body weight
This medicine is not recommended for Deep vein thrombosis (DVT)- prophylaxis if the patients weigh below 50 kg due to the increased risk of bleeding.
-
Platelet Count
This medicine should be used with caution since it may deplete the platelet count and increase the risk of thrombocytopenia. Regular monitoring of the platelet count is necessary while receiving this medicine. It is advised to discontinue the therapy with this medicine if the platelet count falls below 100,000/mm3.
-
Use in Children
This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.
Dosage
-
Missed Dose
This medicine is usually administered in a clinical or hospital setup. However, if you are administering it at home and missed a scheduled dose, then call your doctor immediately for further instructions.
-
Overdose
Seek emergency medical attention in case of an overdose or suspected overdose. Symptoms of an overdose may include nosebleed, unusual bruising and bleeding, and the presence of blood in stool or urine.
Interactions
Interaction with Medicines- Enoxaparin severe
- NSAIDs severe
- Alteplase severe
- Clopidogrel severe
- Warfarin severe
-
severe
This medicine is not recommended for use in patients with a history of bleeding disorders or an active bleeding disorder (inability of the blood to clot normally) due to an increase in the risk of further bleeding. An alternative treatment option should be considered based on the clinical condition.
-
severe
This medicine is not recommended for use in patients with a liver injury/disease due to an increase in the risk of bleeding. Close monitoring of liver function and symptoms like blood in the urine and stools, dizziness, unusual bleeding, etc. are necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
-
severe
This medicine should be used with caution in patients with mild to moderate kidney disease and not recommended in severe kidney disease condition due to the increased risk of worsening of the patient's condition. Regular monitoring of the kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
General Instructions
Administer this medicine exactly as instructed by the doctor. It should not be injected into the muscles. It is advised to administer this medicine under the supervision of a doctor in a clinical setup with regular monitoring of blood clotting time and other related parameters. Your doctor may ask you to undergo certain tests to determine the safety of use of this medicine.
Other details
- Usage does not depend on food timings
- To be taken as instructed by doctor
- Does not cause sleepiness
References
- dailymed - FONDAPARINUX SODIUM [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8a27f341-f612-de72-8c1f-3fd977905de0 [cited 1/6/2021]. 2020
How to use Arixtra Injection 7.5 mg 10 Pre filled Syringex.6 mL
Do not administer IM, only via SC inj. Do not mix with other inj or infusions. Early initiation (before 6 hours after surgery) has been associated with increased bleeding. Rotate injection sites using left and right anterolateral or left and right posterolateral abdominal wall. Do not expel air bubble from prefilled syringe before injection to prevent expelling drug from syringe.
Compatibility: Do not mix with other injections or infusions.
Stability: Store at 25°C (77°F); excursions permitted between 15°C-30°C (59°F-86°F).
what are the adverse effects of Arixtra Injection 7.5 mg 10 Pre filled Syringex.6 mL?
Anaemia, bleeding (incl GI, gingival, utero-vaginal, ocular, haematuria, haematoma, epistaxis, haemoptysis, purpura, bruise), thrombocytopenia (uncommon), abnormal liver function tests, oedema.
What happens if I miss a dose of Arixtra Injection 7.5 mg 10 Pre filled Syringex.6 mL?
Adults: Hip Fracture or Replacement Surgery/ Knee Replacement Surgery/Abdominal Surgery: SC: 2.5 mg daily, starting 6-8 hr post-operation for 5-9 days (Hip/Knees: up to 11 day; Abdominal: up to 10 day). Hip Fracture Surgery: Extended prophylaxis up to 24 additional days.
DVT/PE Treatment: SC: Body weight less than 50 kg: 5 mg daily. Body weight 50-100 kg: 7.5 mg daily. Body weight less than 100 kg: 10 mg daily. Add concomitant warfarin ASAP (usually within 72 hr) and continue for 5-9 days (up to 26 days) until INR is = 2 for at least 24 hrs.
Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Arixtra Injection 7.5 mg 10 Pre filled Syringex.6 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
There are no questions yet. Be the first to ask a question about this product.
Related products
-
CARDIOPARIN 100000IU|ml Injection Pre-fill syringe 1s
Anticoagulants/Platelet deaggregators ₨ 6,844.00 -
-
-
Products listed on medicalstore.com.pk are 100% genuine and sourced from licensed pharmacies.
We work hard to bring you unimaginable discounts without compromising on quality.
We uses SSL (standard security technology) to ensure data privacy of all our customers.
Reviews
There are no reviews yet.