Atropine Injection 1000 mcg 100 Ampx1 mL

 250.00

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 1000 mcg
Drug Form : Injection
Pack Size : 100 Ampx1 mL
Does this requires a prescription ?Yes

Atropine Injection contains Atropine, Inj | belongs to Anticholinergic

SKU: pg_1971_2578 Categories: ,

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    How it works

    Atropine Injection 1000 mcg 100 Ampx1 mL works by blocking the effects of a certain specific chemical (acetylcholine) in various parts of the body.

    Side effects

    Major & minor side effects for Atropine Injection 1000 mcg 100 Ampx1 mL

    • Dry mouth
    • Blurred vision
    • Dry eyes
    • Increased heartbeat
    • Loss of taste
    • Difficulty in breathing
    • Restlessness
    • Drowsiness

    Uses of Atropine Injection 1000 mcg 100 Ampx1 mL

    What is it prescribed for?

    • Bradyarrhythmia

      This medicine is used for the management of bradycardia (slow heart rate) caused by conditions like bradyarrhythmia, heart block, or any other medical conditions by increasing the heart rate and the cardiac output. It also prevents the cholinergic effects on the heart during surgical procedures.

    • Preoperative medication

      This medicine is used as a preoperative medication (before surgeries) to decrease bronchial secretions and excessive salivation.

    • Organophosphate Poisoning

      This medicine acts as an antidote in the treatment of organophosphate poisoning.

    • Radiographic Examinaton

      This medicine is used during some radiographic examination procedures to relax the upper gastrointestinal tract and the colon.

    Concerns

    Frequently asked questions

    • Onset of action

      The effect of this medicine can be observed within 1 hour of administration.

    • Duration of Effect

      The amount of time for which this medicine remains active in the body is 4 hours.

    • Safe with Alchohol?

      It is recommended not to consume alcohol while receiving this medicine due to the increased risk of drowsiness and dizziness. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol while using this medicine. Report any incidence of breathing difficulty or dizziness to the doctor immediately.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Usage in pregnancy?

      This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

    • Usage while breast-feeding?

      This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

    When not to use?

    • Allergy

      This medicine is not recommended for use in patients with a known allergy to Atropine Injection 1000 mcg 100 Ampx1 mL or any other inactive ingredient present along with the formulation.

    • Narrow angle glaucoma

      This medicine is not recommended for use in patients who are suffering from narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.

    • Pyloric stenosis

      This medicine is not recommended for use in patients with a known history of pyloric stenosis since it may worsen the condition.

    • Prostatic hypertrophy

      This medicine is not recommended for use in patients with a known history of prostatic hypertrophy (enlarged prostate) since it may worsen the condition.

    Warnings

    Warnings for special population
    • Pregnancy

      This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

    • Breast-feeding

      This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

    General Warnings
    • Heat intolerance

      This medicine increases the risk of heat intolerance at high temperatures. Report to the doctor if you experience any undesired effects while receiving this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

    • Gastric ulcer

      This medicine has been shown to worsen the condition of a gastric ulcer due to delayed gastric emptying. Discuss the risks and benefits with the doctor before receiving this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

    • Liver diseases

      This medicine should be used with caution in patients with liver diseases due to the increased risk of adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

    • Kidney diseases

      This medicine should be used with caution in patients with kidney diseases due to the increased risk of adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

    • Tachycardia

      This medicine should be used with caution in patients with a known history of tachycardia and unstable heart rate. The use of this medicine may increase the risk of a very high heart rate. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

    Dosage

    • Missed Dose

      Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

    • Overdose

      Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

    Interactions

    Interaction with Medicines
    • Amitriptyline moderate
    • Clozapine moderate
    • Metoclopramide moderate
    • Topiramate severe
    • Ipratropium moderate
    • Dicyclomine moderate
    • Zonisamide severe
    Disease interactions
    • moderate

      This medicine is not recommended for use in patients with a history of myasthenia gravis since it may interact with the medicines given for myasthenia gravis and cause worsening of the condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

    • moderate

      This medicine should be used with extreme caution in patients with a known history of ulcerative colitis due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

    • moderate

      This medicine should be used with caution in patients with a known history of hypertension due to the increased risk of very high blood pressure. Close monitoring of blood pressure is advised while using this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

    • moderate

      This medicine should be used with caution in patients with known history heart diseases due to the increased risk of worsening of the patient's condition. Close monitoring of heart function may be required in patients with heart diseases. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

    General Instructions

    This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.

    Other details

    • Usage does not depend on food timings
    • To be taken as instructed by doctor
    • Causes sleepiness

    References

    Additional Information>

    How to use Atropine Injection 1000 mcg 100 Ampx1 mL

    Intratracheal: Dilute with NS to a volume of 3-5 mL followed by several positive-pressure ventilators. Parenteral: Administer undiluted by rapid IV inj; slow injection may result in paradoxical bradycardia.
    Compatibility: Incompatible with thiopental (Y-site administration), cimetidine/pentobarbital (in syringe), Compatibility when admixed: Incompatible with floxacillin, metaraminol, methohexital, norepinephrine.
    Stability: Store injection at controlled room temperature of 15°C-30°C. Protect from light.

    what are the adverse effects of Atropine Injection 1000 mcg 100 Ampx1 mL?

    Fatigue, delirium, headache, restlessness, ataxia. Dry hot skin. Impaired GI motility. Tremor. Blurred vision. Vomiting, fever, rashes, dizziness, confusion, hallucination, retrosternal pain. Muscarinic effects ( eg, dry mouth, mydriasis, cycloplegia, photophobia, flushing, bradycardia, tachycardia, palpitations and arrhythmias, difficult micturition, constipation, reduced bronchial secretions).

    What happens if I miss a dose of Atropine Injection 1000 mcg 100 Ampx1 mL?

    Premedication: ORAL: For administration by mouth, injection solution may be given orally 1-2 hr before induction of anaesthesia. Children: Neonate, 20-40 mcg/kg. 1 mth-18 yr, 20-40 mcg/kg (max. 900 mcg). INJECTION: IV injection: Immediately before induction of anaesthesia: Children: Neonate, 10 mcg /kg. 1 mth-12 yr, 20 mcg /kg (minimum 100 mcg, max. 600 mcg). 12-18 yr, 300-600 mcg. Adults: 300-600 mcg. SC or IM injection: 30-60 minutes before induction of anaesthesia: Children: Neonate, 10 mcg /kg. 1 mth-12 yr, 10-30 mcg /kg (minimum 100 mcg, max. 600 mcg). 12-18 yr, 300-600 mcg. Adults: 300-600 mcg.
    Intra-operative bradycardia: IV injection: Children: Neonate, 10-20 mcg /kg. 1 mth-12 yr, 10-20 mcg /kg. 12-18 yr, 300-600 mcg (larger doses in emergencies). Adults: 300-600 mcg (larger doses in emergencies).
    Control of muscarinic side-effects of neostigmine 50 mcg /kg in reversal of competitive neuromuscular block: IV injection: Children: Neonate, 20 mcg/kg. 1 mth-12 yr, 20 mcg/kg (max. 1.2 mg). 12-18 yr, 0.6-1.2 mg. Adults: 0.6-1.2 mg.
    Control of muscarinic side-effects of edrophonium in reversal of competitive neuromuscular block: IV injection: Children: 1 mth-18 yr, 7 mcg /kg (max. 600 mcg). Adults: 0.6-1.2 mg.
    Symptomatic relief of gastrointestinal disorders by smooth muscle spasm: Adults: 0.6-1.2 mg.
    Organophosphate or carbamate poisoning: Children: IV: 0.02-0.05 mg/kg every 10-20 min until atropine effect (dry flushed skin, tachycardia, mydriasis, fever) is observed then every 1-4 hr for at least 24 hr. Adults: IV: 1-2 mg/dose every 10-20 min until atropine effect (dry flushed skin, tachycardia, mydriasis, fever) is observed then every 1-4 hr for at least 24 hr; up to 50 mg in first 24 hr and 2 gm over several days may be given in cases of severe intoxication.

    One of the following licensed pharmacy from the nearest location will deliver Atropine Injection 1000 mcg 100 Ampx1 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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