
MBBS
Brukinsa (Zanubrutinib) 80mg 120 Capsule
- Generic Name: Zanubrutinib
- Drug Strength : 80mg
- Pack Size : 120
How It Works
Zanubrutinib, the active ingredient in Brukinsa, works by binding to and inhibiting Bruton’s tyrosine kinase (BTK), an enzyme that plays a crucial role in the survival and proliferation of B-cells. By inhibiting BTK, Brukinsa disrupts the signaling pathways necessary for the growth and survival of malignant B-cells, thereby slowing the progression of the disease.
Side Effects
- Neutropenia (low white blood cell count)
- Upper respiratory tract infection
- Bruising
- Rash
- Anemia (low red blood cell count)
- Thrombocytopenia (low platelet count)
- Muscle pain
- Fatigue
Indications
- Mantle cell lymphoma (MCL) in patients who have received at least one prior therapy
- Chronic lymphocytic leukemia (CLL)
- Waldenström’s macroglobulinemia (WM)
Contraindications
- Hypersensitivity to zanubrutinib or any of its components
- Severe hepatic impairment
- Concomitant use with strong CYP3A inhibitors
Price Comparison in Different Countries
Country | Price (per bottle of 120 capsules) | Reference |
---|---|---|
Pakistan | Approximately PKR 1,000,000 | Dawaai Pakistan |
United States | USD 12,000 | GoodRx |
United Kingdom | GBP 9,000 | NHS UK |
Canada | CAD 15,000 | Health Canada |
Australia | AUD 18,000 | PBS Australia |
Top 5 Global Brands
- Roche
- Novartis
- Pfizer
- Merck & Co.
- Johnson & Johnson
Conclusion
Brukinsa (Zanubrutinib) 80mg is a critical medication for treating specific blood cancers, including mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenström’s macroglobulinemia. By inhibiting the BTK enzyme, it disrupts the growth and survival of malignant B-cells, providing a targeted treatment option for patients. While effective, Brukinsa does come with potential side effects and contraindications that need careful consideration and management. The cost of Brukinsa varies significantly worldwide, highlighting the importance of accessibility and affordability in cancer treatment. Patients should consult their healthcare providers to determine if Brukinsa is suitable for their condition and explore financial assistance options if necessary.
One of the following licensed pharmacy from the nearest location will deliver Brukinsa (Zanubrutinib) 80mg 120 Capsule. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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