MBBS
Calquence (Acalabrutinib) 100 mg Capsule
- Drug Strength : 100mg
- Pack Size : 60
How It Works
Calquence works by inhibiting Bruton’s tyrosine kinase (BTK), an enzyme that plays a crucial role in the survival and proliferation of B-cells. By blocking BTK, Calquence prevents the activation of B-cells, which are often abnormal in blood cancers like MCL and CLL. This inhibition leads to the death of these cancerous cells and reduces their proliferation, thereby controlling the progression of the disease.
Side Effects
- Headache
- Diarrhea
- Fatigue
- Muscle pain
- Bruising
- Infections
- Anemia
- Thrombocytopenia
- Neutropenia
- Upper respiratory tract infections
Indications
- Mantle cell lymphoma (MCL) in patients who have received at least one prior therapy
- Chronic lymphocytic leukemia (CLL)
Contraindications
- Hypersensitivity to acalabrutinib or any of the excipients
- Severe hepatic impairment
- Concurrent use of strong CYP3A inhibitors or inducers
Price Comparison in Different Countries
Country | Price (per bottle of 60 capsules) | Reference |
---|---|---|
Pakistan | Approximately PKR 800,000 | Dawaai Pakistan |
United States | USD 14,000 | GoodRx |
United Kingdom | GBP 11,000 | NHS UK |
Canada | CAD 18,000 | MedBroadcast Canada |
Australia | AUD 20,000 | PBS Australia |
Top 5 Global Brands
- AstraZeneca
- Novartis
- Pfizer
- Roche
- Johnson & Johnson
Conclusion
Calquence (Acalabrutinib) 100 mg capsules offer a vital treatment option for patients with mantle cell lymphoma and chronic lymphocytic leukemia. By targeting and inhibiting Bruton’s tyrosine kinase, it helps manage these types of blood cancers effectively. However, it comes with a range of potential side effects and contraindications that require careful consideration and management by healthcare professionals. The cost of Calquence varies significantly across different countries, highlighting the global disparities in access to cancer treatments. Patients should consult with their healthcare provider to determine if Calquence is the appropriate treatment for their condition and explore possible financial assistance options if needed.
One of the following licensed pharmacy from the nearest location will deliver Calquence (Acalabrutinib) 100 mg Capsule. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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