Carbotinol Injection 50 mg 1 Vialx5 mL

 972.00

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 50 mg
Drug Form : Injection
Pack Size : 1 Vialx5 mL
Does this requires a prescription ?Yes

Carbotinol Injection contains Carboplatin | belongs to Alkylating agent

SKU: pg_3679_4867 Categories: ,

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    How it works

    Carbotinol Injection 50 mg 1 Vialx5 mL works by stopping the growth of cancer cells

    Side effects

    Major & minor side effects for Carbotinol Injection 50 mg 1 Vialx5 mL

    • Pain at the injection site severe
    • Low WBC and Platelet count severe
    • Fever and chills severe
    • Difficult or painful urination severe
    • Skin rash severe
    • Unusual bleeding severe
    • Tingling or numbness of the hands and feet severe
    • Blurred vision severe
    • Ringing or buzzing in the ears severe
    • Nausea and Vomiting
    • Diarrhea
    • Loss of appetite

    Uses of Carbotinol Injection 50 mg 1 Vialx5 mL

    What is it prescribed for?

    • Ovarian Cancer

      Carbotinol Injection 50 mg 1 Vialx5 mL is used in the treatment of cancer that affects the ovaries.

    Concerns

    Frequently asked questions

    • Onset of action

      The peak effect of this medicine can be observed in 2 to 4 hours after intravenous injection.

    • Duration of Effect

      The effect of this medicine lasts for an average duration of 24 hours.

    • Safe with Alchohol?

      Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Usage in pregnancy?

      This medicine is not recommended for pregnant women.

    • Usage while breast-feeding?

      This medicine is not recommended in breastfeeding women.

    When not to use?

    • Allergy

      Not recommended in patients with known allergy to Carbotinol Injection 50 mg 1 Vialx5 mL or other platinum-containing compounds.

    • Significant bleeding

      Not recommended in patients with the bleeding disorder.

    • Severe myelosuppression

      Not recommended in patients with low white blood cell and platelet count.

    Warnings

    Warnings for special population
    • Pregnancy

      This medicine may cause severe kidney injury. The risk may increase if taken with aminoglycoside antibiotics. Close monitoring of serum creatinine, urea, and sodium levels is necessary. Do not administer this medicine more than once every 3 to 4 weeks.

    • Breast-feeding

      This medicine is not recommended in breastfeeding women.

    General Warnings
    • Impaired kidney function

      This medicine may cause severe kidney injury. The risk may increase if taken with aminoglycoside antibiotics. Close monitoring of serum creatinine, urea, and sodium levels is necessary. Do not administer this medicine more than once every 3 to 4 weeks.

    • Hearing impairment

      This medicine may cause the hearing problem which is more common in children. Audiometric testing should be performed before initiating the treatment and also before every dose. Any symptoms of the hearing problem should be reported to the doctor.

    • Allergy

      This medicine may cause serious skin reactions. Discontinue the treatment if any symptoms of allergy appear and do not restart.

    • Blood cell count

      This medicine may lower the white blood cells and platelets. Close monitoring of blood cell count is necessary. Do not start the treatment if the cell count is low.

    • Infections

      The chances of occurring infections are more in patients receiving this medicine. Hold the chemotherapy and start with the broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.

    Dosage

    • Missed Dose

      It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.

    • Overdose

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Interactions

    Interaction with Medicines
    • Clozapine severe
    • Vancomycin moderate
    • Atorvastatin moderate
    • Live vaccines severe

    General Instructions

    This medicine is given in multiple cycles. It is important to receive the every scheduled dose and make a note of next scheduled dose. Close monitoring of blood cells counts and kidney function.

    Other details

    • Usage does not depend on food timings
    • To be taken as instructed by doctor
    • May cause sleepiness

    References

    Additional Information>

    How to use Carbotinol Injection 50 mg 1 Vialx5 mL

    Administer as IV push or bolus over 15 min up to a continuous intravenous infusion over 24 hour. Reconstitute powder to yield a final conc of 10 mg/mL. May also be administered intraperitoneally. When administered as sequential infusions, taxane derivatives (docetaxel, paclitaxel) should be administered before platinum derivatives to limit myelosuppression and to enhance efficacy. Do not use needles or IV administration sets containing aluminium parts that may come in contact with carboplatin (aluminium can react causing precipitate formation and loss of potency).
    Compatibility: Stable in D5¼ NS, D5½ NS, D5NS, D5W, NS.
    Stability: Store at 25°C (77°F); excursions permitted from 15°C-30°C (59°F-86°F). Protect from light. Use carboplatin solutions within 8 hours of reconstitution or preparation when stored at room temperature (25°C; 77°F). When stored in the original multidose vial, the commercially available solution is stable for up to 14 days at room temperature even with multiple needle entries.

    what are the adverse effects of Carbotinol Injection 50 mg 1 Vialx5 mL?

    GI disturbances, neurologic toxicity, myelosuppression, nephrotoxicity.

    What happens if I miss a dose of Carbotinol Injection 50 mg 1 Vialx5 mL?

    Advanced Ovarian Carcinoma: Adults: Single Agent: 360 mg/m² IV on day 1, then every 4 wk. Combination Therapy: 300 mg/m² IV on 1, then every 4 wk x 6 cycles. Adjust based on platelet & neutrophil count.

    One of the following licensed pharmacy from the nearest location will deliver Carbotinol Injection 50 mg 1 Vialx5 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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