Cili-Penem Injection 1 gm 1 Vial

 2,000.00

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 1 gm
Drug Form : Injection
Pack Size : 1 vial
Does this requires a prescription ?Yes

Cili-Penem Injection contains Meropenem | belongs to Carbapenem

SKU: pg_4398_6238 Categories: ,

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    How it works

    Cili-Penem Injection 1 gm 1 Vial is a broad spectrum antibiotic. It works by interfering with the bacterial cell wall synthesis.

    Side effects

    Major & minor side effects for Cili-Penem Injection 1 gm 1 Vial

    • Swelling and redness at the injection site severe
    • Fever severe
    • Confusion severe
    • Fast heartbeat severe
    • Skin rash severe
    • Black or tarry stools severe
    • Decreased urine output severe
    • Diarrhea severe
    • Constipation
    • Body pain
    • Acid or sour stomach
    • White patches in the mouth or on the tongue

    Uses of Cili-Penem Injection 1 gm 1 Vial

    What is it prescribed for?

    • Bacterial Meningitis

      Cili-Penem Injection 1 gm 1 Vial is used in the treatment of Meningitis which is an inflammation of the protective membranes that surround the brain and spinal cord caused by Streptococcus pneumoniae and Neisseria meningitidis.

    • Skin and structure Infection

      Cili-Penem Injection 1 gm 1 Vial is used in the treatment of skin and structure infections like cellulitis, wound infections caused by Streptococcus pyogenes and Staphylococcus aureus.

    • Intra-abdominal Infection

      Cili-Penem Injection 1 gm 1 Vial is used in the treatment of intra-abdominal infections like caused by Escherichia coli and Klebsiella.

    • Pneumonia

      Cili-Penem Injection 1 gm 1 Vial is used in the treatment of Pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.

    Concerns

    Frequently asked questions

    • Onset of action

      The peak effect of this medicine can be observed within 1 hour after intravenous infusion.

    • Duration of Effect

      The effect of this medicine lasts for an average of 3 to 4 hours.

    • Safe with Alchohol?

      Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Usage in pregnancy?

      Limited data is available on the use of this medicine in pregnant women. Use only if clearly needed under the supervision of the doctor.

    • Usage while breast-feeding?

      This medicine can be used by breastfeeding women. Small amount of this medicine is excreted in human breast milk. Monitoring of undesired effects like diarrhea or thrush is necessary.

    When not to use?

    • Allergy

      Avoid if you have a known allergy to Cili-Penem Injection 1 gm 1 Vial or any other carbapenem antibiotics and beta-lactam antibiotics.

    Warnings

    Warnings for special population
    • Pregnancy

      Limited data is available on the use of this medicine in pregnant women. Use only if clearly needed under the supervision of the doctor.

    • Breast-feeding

      This medicine can be used by breastfeeding women. Small amount of this medicine is excreted in human breast milk. Monitoring of undesired effects like diarrhea or thrush is necessary.

    General Warnings
    • Allergy

      Avoid if you have a known allergy to Cili-Penem Injection 1 gm 1 Vial or any Carbapenem and Beta-lactam Antibiotics like penicillins and cephalosporins. Seek immediate medical attention if the patient experiences any allergic symptoms like rash, itching, nausea or vomiting, swelling of lips, hands, and feet.

    • Drug-resistance

      Usage of Cili-Penem Injection 1 gm 1 Vial without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

    • Clostridium difficile-associated Diarrhea

      Avoid if you experience severe diarrhea after receiving Cili-Penem Injection 1 gm 1 Vial . As antibiotic therapy will cause an imbalance in the normal microbial flora in the large intestine which promotes the growth of bacteria called Clostridium difficile.

    • Seizures

      Cili-Penem Injection 1 gm 1 Vial may cause seizures and other central nervous system disturbances. Use with caution in the patients with a history of seizures or any brain infections.

    • Pediatric use

      The safety and efficacy of Cili-Penem Injection 1 gm 1 Vial is not established in children less than 3 months of age.

    • Impaired kidney function

      Use with caution the patients with the kidney injury. Dose adjustments are to be made if CrCl is less than 50 ml/min.

    Dosage

    • Missed Dose

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Overdose

      Seek emergency medical treatment or contact the doctor in case of overdose.

    Interactions

    Interaction with Medicines
    • Tramadol severe
    • Ethinyl Estradiol moderate
    • Cholera Vaccine severe
    • Valporic Acid severe
    Disease interactions
    • severe

      Cili-Penem Injection 1 gm 1 Vial may cause seizures, confusion, and agitation. Use with caution the patients with seizures or any central nervous system disorders.

    • moderate

      Avoid if you experience severe diarrhea, abdominal pain, and blood in stools after taking Cili-Penem Injection 1 gm 1 Vial . Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.

    General Instructions

    Make sure that the medicine is dissolved properly. Do not take if any particulate matter is visible. Consult the doctor if you experience any undesirable effects. Do not stop taking before completion of course.

    Other details

    • Food timings: Information not available
    • Administration time: Information not available
    • Sleep inducing: Information not available

    References

    Additional Information>

    How to use Cili-Penem Injection 1 gm 1 Vial

    Dilute in 50-200 mL infusion fluid & give over 15-30 min. Doses of 1 gm also may be administered as an IV bolus injection (5-20 mL) over approx 3-5 min.
    Compatibility: Stable in D5W, D10W or NS.
    Y-site administration:
    Drug to Drug IV Compatibility: Calcium gluconate, cimetidine, dexamethasone, digoxin, diltiazem, diphenhydramine, dobutamine, dopamine, enalapril, fluconazole, furosemide, gentamicin, heparin, hydromorphone, insulin regular, linezolid, lorazepam, magnesium sulphate, metoclopramide, milrinone, morphine, norepinephrine, ranitidine, vancomycin, vasopressin.
    Drug to Drug IV Incompatibility: Acyclovir, amphotericin B, diazepam, metronidazole, ondansetron.
    When admixed: Incompatible with amphotericin B, metronidazole.
    Stability: Store dry powder at 20°C-25°C (68°F-77°F). Freshly prepared solutions should be used whenever possible. Reconstituted solutions are stable at 15°C-25°C (59°F-77°F), or under refrigeration at 4°C (39°F). Solutions of meropenem should not be frozen. Solutions constituted with SWFI for bolus administration (meropenem up to 50 mg/mL) may be stored for up to 2 hours at 15°C-25°C (59°F-77°F), or for up to 12 hours at 4°C (39°F).

    what are the adverse effects of Cili-Penem Injection 1 gm 1 Vial?

    Rash, abdominal pain, nausea, diarrhoea, candidiasis, pseudomembranous colitis, pruritus, inflammation, altered LFTs, haematological reactions.

    What happens if I miss a dose of Cili-Penem Injection 1 gm 1 Vial?

    Adults: 500 mg-1 gm by IV bolus inj over 5 min or by IV infusion over 15-30 min every 8 hr.
    Meningitis: 2 gm every 8 hr.
    Children: Under 3 mth, not recommended; over 3 mth, 10- 20 mg/kg by IV bolus inj over 5 min or by IV infusion over 15- 30 min every 8 hr.
    Meningitis: 40 mg/kg every 8 hr.

    One of the following licensed pharmacy from the nearest location will deliver Cili-Penem Injection 1 gm 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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