Cleocin Injection 600 mg 5 Ampx4 mL

 700.00

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 600 mg
Drug Form : Injection
Pack Size : 5 Ampx4 mL

Cleocin Injection contains Clindamycin, Inj/Oral | belongs to Lincosamide

SKU: pg_4791_6828 Categories: ,

Alternate brands of Cleocin Injection 600 mg 5 Ampx4 mL

Brand Name Price Savings
Simklin capsule 150 mg 20’s  129.60 You can save 570.4
Klinda capsule 300 mg 16’s  280.00 You can save 420
Klinda capsule 150 mg 16’s  150.00 You can save 550
Jalacin capsule 150 mg 16’s  150.00 You can save 550
Jalacin capsule 300 mg 16’s  275.00 You can save 425
List of alternate brands

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How it works

Cleocin Injection 600 mg 5 Ampx4 mL works primarily by binding to the 50s ribosomal subunit of bacteria. This agent disrupts protein synthesis by interfering with the transpeptidation reaction, which thereby inhibits early chain elongation.

Side effects

Major & minor side effects for Cleocin Injection 600 mg 5 Ampx4 mL

  • Scaly skin severe
  • Black or tarry stools severe
  • Nausea
  • Chest pain severe
  • Diarrhea severe
  • Abdominal pain
  • Fast heartbeat severe
  • Muscle or joint pain severe
  • Increased thirst severe

Uses of Cleocin Injection 600 mg 5 Ampx4 mL

What is it prescribed for?

  • Lower Respiratory Tract Infection

    This medicine is used in the treatment of infections of the lower respiratory tract such as bronchitis, pneumonia, etc. caused by susceptible staphylococcal, pneumococcal, and streptococcal species as well as anaerobic bacteria.

  • Skin and Skin Structure Infection

    This medicine is used in the treatment of skin and skin structure infections caused by susceptible staphylococcal and streptococcal species as well as anaerobic bacteria.

  • Intra-abdominal Infections

    This medicine is used in the treatment of intra-abdominal infections such as peritonitis, intra-abdominal abscess, etc. caused by susceptible anaerobic bacteria.

  • Gynecological infections

    This medicine is used in the treatment of gynecological infections such as vulvitis, vaginitis, endometritis, etc. caused by susceptible anaerobic bacteria.

  • Bone and Joint infections

    This medicine is used as an adjunctive therapy along with surgical procedures for the treatment of chronic bone and joint infections caused by susceptible bacteria.

Concerns

Frequently asked questions

  • Onset of action

    The effect of this medicine can be observed within 1 to 3 hours after an intramuscular administration and rapidly after an intravenous administration.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 6 to 8 hours.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit-forming tendencies were reported.

  • Usage in pregnancy?

    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is necessary. Your doctor may prescribe a safer alternative based on your clinical condition.

When not to use?

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to Cleocin Injection 600 mg 5 Ampx4 mL , any other lincosamides, or any other inactive ingredients present along with it.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

  • Breast-feeding

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is necessary. Your doctor may prescribe a safer alternative based on your clinical condition.

General Warnings
  • Clostridium difficile-associated Diarrhea

    Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this medicine in such cases.

  • Drug-resistance

    Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

  • Skin reactions

    Usage of this medicine is known to cause severe skin reactions such as toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS), and Stevens-Johnson syndrome (SJS), etc. in rare cases, some with fatal outcomes. Report any unusual symptoms to the doctor on priority. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

  • Gasping syndrome

    Some formulations of this medicine may contain benzyl alcohol; these formulations increase the risk of the gasping syndrome in the newborns. Formulations without benzyl alcohol may be preferred for such patients.

  • Impaired liver function

    This medicine should be used with caution in patients with a known history of an impaired liver function due to the increased risk of severe adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

  • Impaired kidney function

    This medicine should be used with caution in patients with a known history of an impaired kidney function due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

  • Intravenous Administration

    When used intravenously, the infusion rate of the medicine varies based on the prescribed dose.

Dosage

  • Missed Dose

    Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.

  • Overdose

    Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions

Interaction with Medicines
  • Gentamicin moderate
  • Ethinyl Estradiol moderate
  • Cholera Vaccine severe
  • Verapamil moderate
  • Erythromycin moderate
  • Cyclosporine moderate
Disease interactions
  • moderate

    This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, due to the increased risk of worsening of the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

  • moderate

    This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

  • moderate

    This medicine should be used with caution in patients with renal diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

General Instructions

This medicine should be administered by a qualified healthcare professional in the clinical or hospital setting. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Report any undesirable side effects to the doctor promptly.

Other details

  • Usage does not depend on food timings
  • To be taken as instructed by doctor
  • Does not cause sleepiness

References

Additional Information>

How to use Cleocin Injection 600 mg 5 Ampx4 mL

IM: Deep IM, rotate sites. Do not exceed 600 mg in a single injection. IV: Never give as bolus. Administer by IV intermittent infusion over at least 10-60 min, at a rate not to exceed 30 mg/min; final concentration for administration should not exceed 12 mg/ mL.
Reconstitution: Dilute 300 mg in 50 mL of diluent and give over 10 mins. Dilute 600 mg in 100 mL of diluent and give over 20 mins. Dilute 900 mg in 100 mL of diluent and give over 30 mins.
Compatibility: Stable in D5LR, D5½NS, D5NS, D5W, D10W, LR, NS. At Y-site administration, incompatible with allopurinol, filgrastim, fluconazole, idarubicin. In syringe, incompatible with tobramycin. When admixed, incompatible with aminophylline, barbiturates, calcium gluconate, ceftriaxone, ciprofloxacin, gentamicin with cephazolin, magnesium sulphate, phenytoin.
Stability: IV infusion solution in NS or D5W solution is stable for 16 days at room temperature.

what are the adverse effects of Cleocin Injection 600 mg 5 Ampx4 mL?

Gl disturbances including pseudomembranous colitis. Jaundice and blood disorders.

What happens if I miss a dose of Cleocin Injection 600 mg 5 Ampx4 mL?

ORAL: Adults: 150-450 mg six hourly. Children: Under 1 yr, 2.5-5 mL; 4-7 yr, 5-7.5 mL; 8-12 yr, 7.5-10 mL. All six hourly.
Lower Respiratory Infection: Adults: 150-450 mg every 6 hr. Children: 8-20 mg/kg/day given in 3-4 doses.
Bone Infection: Adults: 150-450 mg every 6 hr. Children: 8-20 mg/kg/day given in 3-4 doses.
Skin Infection: Adults: 150-450 mg every 6 hr. Children: 8-20 mg/kg/day given in 3-4 doses.
Bacterial Vaginosis: Pregnant/Non-Pregnant: 300 mg every 12 hr for 7 days.
INJECTION: Adults: 600 mg-2.7 gm by IM, inj or IV infusion daily in divided doses. Children: Over 1 mth, 15-40 mg/kg daily in divided doses.
Lower Respiratory Infection: IM/IV: Adults: 600-2700 mg/day in 2-4 doses. Max: 600 mg IM single dose. Children: 1 mth-16 yr: 20-40 mg/kg/day in 3-4 doses. lt; 1 mth: 15-20 mg/kg/day
Bone Infection: IM/IV: Adults: 600-2700 mg/day in 2-4 doses. Max: 600 mg IM single dose. Children: 1 mth-16 yr: 20-40 mg/kg/day in 3-4 doses. lt;1 mth: 15-20 mg/kg/day in 3-4 doses.
Skin Infection: IM/IV: Adults: 600-2700 mg/day in 2-4 doses. Max: 600 mg IM single dose. Children: 1 mth-16 yr: 20-40 mg/kg/day in 3-4 doses. lt;1 mth: 15-20 mg/kg/day in 3-4 doses.
Septicaemia: IV: Adults: 1200-2700 mg/day given in two or four divided doses. Up to 4800 mg/day. Children: 1 mth-16 yr: 20-40 mg/kg/day given in 3-4 doses. lt;1 mth: 15-20 mg/kg/day given 3-4 doses.

One of the following licensed pharmacy from the nearest location will deliver Cleocin Injection 600 mg 5 Ampx4 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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