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Co-Losartin tablet 50/12.5 mg 2x10's

Co-Losartin tablet contains Losartan and Hydrochlorothiazide | belongs to Angiotensin II antagonist/Thiazide diuretic

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How it works

Co-Losartin tablet 50/12.5 mg 2×10’s relaxes the heart muscles and the blood vessels. It relaxes the blood vessels and promotes the smooth flow of blood. Their combination is thus effective in reducing blood pressure and the strain on the heart.

Side effects

Major & minor side effects for Co-Losartin tablet 50/12.5 mg 2×10’s

  • Stomach severe
  • Chills severe
  • Difficulty or painful urination severe
  • Back pain severe
  • Chest tightness severe
  • Weakness in arms, hands, legs or feet severe
  • Swelling of ankles or feet severe
  • Difficulty in breathing severe
  • Dizziness severe
  • Increased heartbeat severe
  • Redness of face, neck, arms and chest severe
  • Redness of face, neck, arms and chest severe

Uses of Co-Losartin tablet 50/12.5 mg 2×10’s

What is it prescribed for?

  • Hypertension

    This medicine is used in the treatment of high blood pressure which may be caused by genetic or environmental factors.

Concerns

Frequently asked questions

  • Onset of action

    The effect of this medicine can be observed within 1 hour of administration of the dose.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 24 hours.

  • Safe with Alchohol?

    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

  • Is it habit forming?

    No habit-forming tendencies were reported.

  • Usage in pregnancy?

    This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

When not to use?

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to amlodipine, other calcium-channel blockers, losartan, or any other angiotensin receptor blockers.

  • Aliskiren

    Coadministration of aliskiren and this combination medicine is not recommended due to the increased risk of serious adverse effects. This risk is especially higher in the elderly population and in patients with diabetes and kidney diseases.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

  • Breast-feeding

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Warnings

Warnings for special population
  • Hyperkalemia

    This medicine may increase the potassium levels in the blood (hyperkalemia). This may cause serious side effects such as fatal cardiac rhythm irregularities. It is advised to avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (potassium-sparing diuretics and potassium supplements) during treatment with this medicine.

  • Use in pediatrics

    This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

  • Coronary artery diseases

    This medicine should be used with caution in patients with coronary artery diseases since it may worsen the patient's condition. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

  • Impaired liver function

    This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

  • Aortic stenosis

    This medicine should be used with extreme caution in patients suffering from aortic stenosis due to the increased risk of a very low blood pressure. Close monitoring of blood pressure is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

  • Driving and operating machines

    This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Dosage

  • Missed Dose

    Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

Interaction with Medicines
  • Carbamazepine moderate
  • Itraconazole severe
  • Lithium moderate
  • Corticosteroids moderate
  • Rifampicin severe
  • Aliskiren severe
  • Captopril severe
  • Insulin moderate
  • Nonsteroidal anti-inflammatory medicines moderate
Disease interactions
  • moderate

    This medicine should be used with caution in patients with congestive heart failure since it may worsen the patient's condition. Close monitoring of blood pressure, electrolytes level, and heart function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

  • severe

    This medicine is not recommended for use in patients suffering from a cardiogenic shock since it may worsen the patient's condition.

Food interactions
  • Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects such as dizziness, headache, swelling of hands and feet, etc.

Lab interactions

General Instructions

Take this medicine exactly as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • May cause sleepiness

References

what are the adverse effects of Co-Losartin tablet 50/12.5 mg 2×10’s

Dizziness, orthostatic effects, diarrhoea, liver function abnormalities, myalgia, migraine, urticaria, pruritus, rash. Rarely, anaphylactic reactions, angioedema, vasculitis, hepatitis, cough, anaemia, asthaenia, fatigue, musculoskeletal or chest pain, hypotension, electrolyte disturbances, hypoglycaemia, headache, insomnia, GI upset, cough, upper RTI, renal impairment, reduced haematocrit or haemoglobin.

What is the dose of Co-Losartin tablet 50/12.5 mg 2×10’s

Adults: Initially 1 tab daily. Increased to max 100 mg losartan daily if necessary. Children: Not recommended.

One of the following licensed pharmacy from the nearest location will deliver Co-Losartin tablet 50/12.5 mg 2×10’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

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