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Curosurf Injection 80 mg/mL 1 Vialx1.5 mL

Belongs to Category,

Curosurf Injection contains Poractant Alfa | belongs to Lung surfactant

How it works

Curosurf Injection 80 mg/mL 1 Vialx1.5 mL works by reducing the surface tension within the alveoli of the lungs and improves breathing.

Side effects

Major & minor side effects for Curosurf Injection 80 mg/mL 1 Vialx1.5 mL

  • Bleeding from lungs severe
  • Decreased heartbeat severe
  • Decreased blood pressure rare

Uses of Curosurf Injection 80 mg/mL 1 Vialx1.5 mL

What is it prescribed for?

  • Neonatal Respiratory Distress Syndrome

    This medicine is used for the prevention and treatment of respiratory distress syndrome (RDS) in newborn babies. It occurs when the baby's lung function decreases which may lead to serious breathing difficulties.

Concerns

Frequently asked questions

  • Onset of action

    The amount of time required for this medicine to show its action is not clinically established.

  • Duration of Effect

    The amount of time for which this medicine remains active in the body is not clinically established.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit-forming tendencies were reported

  • Usage in pregnancy?

    This medicine is not recommended for use in pregnant women.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use in pregnant women.

  • Breast-feeding

    This medicine is not recommended for use in breastfeeding women.

General Warnings
  • Birth weight

    Care must be taken for use in newborn babies with very low birth-weight due to an increase in the risk of pulmonary hemorrhage (bleeding from lungs) and other severe adverse effects. Close monitoring of heart rate and arterial oxygenation is recommended during treatment with this medicine.

  • Intratracheal administration

    The medicine should be administered through intratracheal route only.

  • Mucous plugging

    In newborns whose ventilation becomes notably impaired during or immediately after the therapy with this medicine may have mucus plugging of the endotracheal tube. Therefore, it is recommended to perform suctioning of all newborns to avoid endotracheal tube obstruction due to mucous plugging.

Dosage

  • Missed Dose

    Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

  • Overdose

    Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

General Instructions

This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor about all the current medicines as well as medical conditions of your infants before beginning treatment with this medicine.

Other details

  • Usage does not depend on food timings
  • To be taken as instructed by doctor
  • Does not cause sleepiness

References

Additional Information:

How to use Curosurf Injection 80 mg/mL 1 Vialx1.5 mL

For intratracheal use only. Before administering, ensure proper placement and patency of the endotracheal tube. At the discretion of the clinician, the endotracheal tube may be suctioned before administering poractant alfa. Allow the infant to stabilize before proceeding with dosing.
Stability: Store in a refrigerator at 2°C-8°C (36°F-46°F). Unopened vials may be warmed to room temperature for up to 24 hours prior to use. Unopened, unused vials that have warmed to room temperature may be returned to refrigerated storage within 24 hours for future use. Do not warm to room temperature or return it to the refrigerator more than once. Protect from light. Enter each single-use vial only once and discard the vial with any unused material after the initial entry.

what are the adverse effects of Curosurf Injection 80 mg/mL 1 Vialx1.5 mL?

Pulmonary haemorrhage (rarely), especially in more preterm neonates.

What happens if I miss a dose of Curosurf Injection 80 mg/mL 1 Vialx1.5 mL?

By endotracheal tube, treatment, 100-200 mg/kg; further doses of 100 mg/kg may be repeated 12 hr later and after further 12 hr if still intubated; max total dose, 300-400 mg/kg; prophylaxis, 100-200 mg/kg soon after birth (preferably within 15 min); further doses of 100 mg/kg may be repeated 6-12 hr later and after further 12 hr if still intubated; max total dose 300-400 mg/kg.

One of the following licensed pharmacy from the nearest location will deliver Curosurf Injection 80 mg/mL 1 Vialx1.5 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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