₨ 358.00
MBBS
Cyclomide Injection 1 gm 1 Vial
- Does this requires a prescription ? Yes
- Generic Name: Cyclophosphamide
- Manufactured by : Pharmedic Laboratories
- Drug Strength : 1 gm
- Drug Form : Injection
- Pack Size : 1 vial
- Product SKU : pg_5507_7712
Cyclomide Injection contains Cyclophosphamide | belongs to Alkylating agent
Alternate brands of Cyclomide Injection 1 gm 1 Vial
Brand Name | Price | Savings |
---|---|---|
Zycram Injection 1 gm 1 Vial | ₨ 358.00 | You can save 0 |
Zycram Injection 500 mg 1 Vial | ₨ 225.00 | You can save 133 |
Zycram Injection 200 mg 1 Vial | ₨ 65.65 | You can save 292.35 |
Cyclophophamide Injection 500 mg 10 Vial | ₨ 120.00 | You can save 238 |
Cyclomide Injection 500 mg 1 Vial | ₨ 225.00 | You can save 133 |
How it works
Cyclomide Injection 1 gm 1 Vial works by slowing or stopping the growth of cancer cells in your body.
Side effects
Major & minor side effects for Cyclomide Injection 1 gm 1 Vial
- Infections severe
- Decrease in blood cell count severe
- Hair loss severe
- Fever severe
- Weakness severe
- Loss of appetite
- Nausea and Vomiting
- Diarrhea
- Headache
- Increased sweating
- Skin rash
Uses of Cyclomide Injection 1 gm 1 Vial
What is it prescribed for?
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Malignant Disease
Cyclomide Injection 1 gm 1 Vial is used in the treatment of cancers like Hodgkin’s disease, lymphocytic lymphoma, etc.
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Ovarian Cancer
Cyclomide Injection 1 gm 1 Vial is used in the treatment of the cancer that affects the female reproductive system.
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Breast cancer
Cyclomide Injection 1 gm 1 Vial is used in the treatment of breast cancer.
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Nephrotic Syndrome
In pediatrics, if the nephrotic syndrome does not respond adequately to steroid treatments or if the steroids produce intolerable side effects, Cyclomide Injection 1 gm 1 Vial is used to treat the condition.
Concerns
Frequently asked questions
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Onset of action
The effect of this medicine can be observed in 2 to 3 hours after an oral dose.
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Duration of Effect
The effect of this medicine lasts for an average duration of 12 to 24 hours.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit forming tendency has been reported.
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women.
When not to use?
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Allergy
Not recommended in patients with known allergy to Cyclomide Injection 1 gm 1 Vial or other alkylating agents.
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Urinary outflow obstruction
Not recommended in patients with conditions that obstruct the urine outflow.
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Bone marrow suppression
Not recommended in patients with low blood cell counts.
Warnings
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Pregnancy
This medicine is not recommended for use in pregnant women.
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Breast-feeding
This medicine is not recommended for use in breastfeeding women.
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Secondary Malignancies
Cyclomide Injection 1 gm 1 Vial is known to increase the risk of secondary tumors. Most frequently, the urinary tract, thyroid gland, and blood are affected. Close monitoring of signs and symptoms is necessary. The treatment should be discontinued if malignancy develops.
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Blood cell count
Cyclomide Injection 1 gm 1 Vial is known to lower the white blood cell count (neutrophils) and platelets. Close monitoring of blood cell counts is necessary. Do not start the treatment if the neutrophils count is less than 1500 cells/mm3 and platelets count is less than 50,000 cells/mm3.
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Effect on heart
Cyclomide Injection 1 gm 1 Vial may increase the risk of toxic effects on the heart and could lead to congestive heart failure. The treatment should be monitored in patients with a history of heart disease.
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Effect on lungs
Cyclomide Injection 1 gm 1 Vial may increase the risk of toxic effects on lungs and could lead to respiratory failure. Any symptoms of lung toxicity should be informed to the doctor on priority. The treatment should be discontinued if such symptoms appear.
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Infections
The chances of infections are more in patients receiving this medicine. Hold the chemotherapy and start with broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.
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Impaired kidney function
Cyclomide Injection 1 gm 1 Vial is known to increase kidney injury and increases the risk of secondary cancers. It should be used with caution in patients with urinary tract infections. The treatment should be discontinued if the signs and symptoms of kidney injury appear.
Dosage
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Missed Dose
It is advised not to miss any dose. If you miss any dose, you should contact your doctor immediately.
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Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Clozapine severe
- Diltiazem moderate
- Warfarin moderate
- Live attenuated vaccines and related products severe
General Instructions
Take this medicine as advised by the doctor. It should be given in multiple cycles along with other chemotherapy agents. It is important to receive every scheduled dose. The blood cells count and kidney function should be assessed before starting the treatment. Any signs and symptoms of heart and lung dysfunction should be reported to the doctor on priority.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- Does not cause sleepiness
References
- medlineplus.gov - Cyclophosphamide [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a682080.html [cited 21/7/2020]. 2020
How to use Cyclomide Injection 1 gm 1 Vial
IV: May be administered IP, intrapleurally, IVPB, or continuous intravenous infusion, may also be administered slow IVP in doses lt;1 gm. IV infusions may be administered over 1-24 hours. Doses gt;500 mg to approximately 2 g may be administered over 20-30 min. To minimize bladder toxicity, increase normal fluid intake during and for 1-2 days after cyclophosphamide dose. Most adult patients will require a fluid intake of at least 2 litre/day. High-dose regimens should be accompanied by vigorous hydration with or without mesna therapy. Reconstitute vials with SWI, NS, or D5W to a concentration of 20 mg/mL.
Compatibility: Stable in D5LR, D5W, D5NS, LR, ½NS, NS.
Stability: Store at or below 25°C (77°F). Do not use cyclophosphamide if there are signs of melting. Solutions for injection are stable for 24 hours at room temperature or up to 6 days under refrigeration. However, reconstituted solutions are preservative free and should be used within 24 hours.
what are the adverse effects of Cyclomide Injection 1 gm 1 Vial?
Nausea, vomiting, alopecia, reticule-endothelial suppression, haematuria, urothelial toxicity.
What happens if I miss a dose of Cyclomide Injection 1 gm 1 Vial?
INJECTION: Adults & Children: IV: 40-50 mg/kg in divided doses over 2-5 days, or 10-15 mg/kg for 7-10 days, or 3-5 mg/kg.
ORAL: Adults & Children: 1-5 mg/kg/day.
One of the following licensed pharmacy from the nearest location will deliver Cyclomide Injection 1 gm 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
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1 review for Cyclomide Injection 1 gm 1 Vial
aneela –
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