₨ 20,425.90
MBBS
Cymevene Injection 500 mg 5 Vial
- Does this requires a prescription ? Yes
- Generic Name: Ganciclovir
- Manufactured by : Roche
- Drug Strength : 500 mg
- Drug Form : Injection
- Pack Size : 5 Vial
- Product SKU : pg_5532_7738
Cymevene Injection contains Ganciclovir | belongs to DNA polymerase inhibitor
Alternate brands of Cymevene Injection 500 mg 5 Vial
Brand Name | Price | Savings |
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Ganvir capsule 250 mg 36’s | ₨ 5,400.00 | You can save 15025.9 |
Ganvir Injection 250 mg 1 Vial | ₨ 655.00 | You can save 19770.9 |
Gantovir Injection 250 mg 1 Vial | ₨ 655.00 | You can save 19770.9 |
How it works
Cymevene Injection 500 mg 5 Vial works by preventing the spread of CMV disease or slowing the growth of CMV.
Side effects
Major & minor side effects for Cymevene Injection 500 mg 5 Vial
- Chills severe
- Headache severe
- Shortness of breath severe
- Diarrhea severe
- Abdominal and stomach pain severe
- Nausea and Vomiting
- Back pain
- Seizures
- Swelling of legs
- Itching
- Decreased urine output
Uses of Cymevene Injection 500 mg 5 Vial
What is it prescribed for?
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Cytomegalovirus Retinitis (CMV)
Cymevene Injection 500 mg 5 Vial is used in the treatment of Cytomegalovirus Retinitis in adults with acquired immunodeficiency syndrome (AIDS).
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Cytomegalovirus Prophylaxis
Cymevene Injection 500 mg 5 Vial is used in the prevention of Cytomegalovirus infection in patients who have undergone an organ transplantation and are at risk of CMV disease.
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Acute herpetic keratitis
The topical form of this medicine is used in the treatment of Acute herpetic keratitis.
Concerns
Frequently asked questions
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Onset of action
The amount of time required for this medicine to show its effect is not clinically established.
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Duration of Effect
The time until which this medicine remains active in the body is not clinically established.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit forming tendency has been reported
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women except in life-threatening conditions. Discuss all the risks and benefits with your doctor before taking this medicine.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor may advise you to discontinue the medicine or to discontinue breastfeeding based on your clinical condition. Discuss all the risks and benefits with your doctor before taking this medicine.
When not to use?
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Allergy
This medicine is not recommended for use in patients with a known allergy to Cymevene Injection 500 mg 5 Vial or any other medicine of the same class.
Warnings
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Pregnancy
This medicine is not recommended for use in pregnant women except in life-threatening conditions. Discuss all the risks and benefits with your doctor before taking this medicine.
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Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor may advise you to discontinue the medicine or to discontinue breastfeeding based on your clinical condition. Discuss all the risks and benefits with your doctor before taking this medicine.
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Hematologic Toxicity
This medicine should be used with caution in patients with a known history of blood disorders due to the increased risk of worsening of the patient's condition. Close monitoring of blood cell counts is necessary while receiving treatment with this medicine. Replacement with a suitable alternative may be required based on the clinical condition of the patient.
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Renal dysfunction
Cymevene Injection 500 mg 5 Vial should be used with extreme caution in patients with renal diseases due to the increased risk of severe side effects. Appropriate dose adjustments may be necessary based on the clinical condition of the patient.
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Impairment of Fertility
This medicine should be used with caution due to the increased risk of impairment of fertility in both men and women. Replacement with a suitable alternative may be required based on the clinical condition of the patient. Do not stop the use of any medicine without consulting your doctor.
Dosage
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Missed Dose
If an oral dose of Cymevene Injection 500 mg 5 Vial is missed, take the dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose and take the next dose. Do not double the dose to make up for the missed one. Since the intravenous form of this medicine is usually administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of missing a dose is very low. Gel: If the dose Cymevene Injection 500 mg 5 Vial gel is missed, instill it as soon as you remember. Skip the missed dose if it is almost time for the next scheduled dose. Do not use extra medicine to make up for the missed dose.
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Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Clozapine severe
- Infliximab severe
- Zidovudine severe
- Didanosine moderate
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severe
This medicine should be used with extreme caution in patients with a known history of blood disorders and bone marrow suppression due to the increased risk of worsening of the patient's condition. You may require a dose adjustment and more frequent complete blood count monitoring to safely use this medicine. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
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severe
Cymevene Injection 500 mg 5 Vial should be used with extreme caution in patients with kidney diseases due to the increased risk of severe adverse effects. Kidney function should be assessed before initiating the treatment. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
General Instructions
Use Cymevene Injection 500 mg 5 Vial exactly as instructed by the doctor. Do not use larger or smaller amounts than prescribed. Ensure that the course of treatment is completed. Report any adverse effects to the doctor on priority. Do not stop the use of this medicine without consulting your doctor.
Other details
- To be taken with food
- To be taken as instructed by doctor
- May cause sleepiness
References
- medlineplus.gov - Ganciclovir [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a605011.html [cited 28/7/2020]. 2020
How to use Cymevene Injection 500 mg 5 Vial
Administered by IV infusion. After reconstitution the required dose may be diluted in 50-250 mL (usually 100 mL) of compatible infusion solution and given over 1 hour. Concentration greater than 10 mg/mL are not recommended.
Reconstitution: Reconstitute powder with unpreserved sterile water, dilute in 250-1000 mL D5W or NS to a concentration =10 mg/mL for infusion.
Compatibility: Stable in D5W, LR, NS. Incompatible with bacteriostatic WFI.
Stability: Intact vial should be stored at room temperature and protected from temperatures gt;40°C. Reconstituted solution is stable for 12 hours at room temperature. Stability at room temperature (25°C) and at refrigeration temperature (4°C) is 5 days.
what are the adverse effects of Cymevene Injection 500 mg 5 Vial?
Diarrhoea, nausea, vomiting, dyspepsia, abdominal pain, constipation, flatulence, dysphagia, hepatic dysfunction; dyspnoea, chest pain, cough; headache, insomnia, convulsions, dizziness, neuropathy, depression, anxiety, confusion, abnormal thinking, fatigue, weight loss, anorexia; infection, fever, night sweats; anaemia, leucopenia, thrombocytopenia, pancytopenia, renal impairment; myalgia, arthralgia; macular oedema, retinal detachment, vitreous floaters, eye pain; ear pain, taste disturbance; dermatitis, pruritus; injection-site reactions; less commonly mouth ulcers, pancreatitis, arrhythmias, hypotension, anaphylactic reactions, psychosis, tremor, male infertility, haematuria, disturbances in hearing and vision and alopecia.
What happens if I miss a dose of Cymevene Injection 500 mg 5 Vial?
INJECTION: Adults & Children: Above 3 mth age: By IV infusion, initially (induction) 5 mg/ kg every 12 hr for 14-21 days for treatment or for 7-14 days for prevention; maintenance (for patients at risk of relapse of retinitis) 6 mg/kg daily on 5 days per wk or 5 mg/kg daily until adequate recovery of immunity; if retinitis progresses initial induction treatment may be repeated.
ORAL: Adults: CMV disease: 1000 mg 3 times daily or 500 mg 6 times daily.
One of the following licensed pharmacy from the nearest location will deliver Cymevene Injection 500 mg 5 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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