Dabenzole Infusion 100 mg 1 Vial

 20,000.00

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 100 mg
Drug Form : Infusion
Pack Size : 1 vial

Dabenzole Infusion contains Oxaliplatin | belongs to Alkylating agent

SKU: pg_5650_7893 Categories: ,

Alternate brands of Dabenzole Infusion 100 mg 1 Vial

Brand Name Price Savings
Xaliplatin Infusion 100 mg 1 Vial  20,000.00 You can save 0
Xaliplatin Infusion 50 mg 1 Vial  10,000.00 You can save 10000
Plaxinol Infusion 50 mg 1 Vial  9,500.00 You can save 10500
Oxitan Infusion 50 mg 1 Vial  10,000.00 You can save 10000
Oxitan Infusion 100 mg 1 Vial  20,000.00 You can save 0
List of alternate brands

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How it works

Dabenzole Infusion 100 mg 1 Vial works by stopping the growth of cancer cells by inhibiting the DNA synthesis.

Side effects

Major & minor side effects for Dabenzole Infusion 100 mg 1 Vial

  • Burning or tingling sensation of hands and feet severe
  • Cough severe
  • Fever and chills severe
  • Low WBC and Platelet count severe
  • Mouth ulcers severe
  • Loss of appetite severe
  • Skin rash severe
  • Nausea and Vomiting severe
  • Swelling of eyelids, face, lips severe
  • Acid or sour stomach
  • Sneezing
  • Stomach discomfort and pain
  • Running Nose
  • Change in taste
  • Hair loss

Uses of Dabenzole Infusion 100 mg 1 Vial

What is it prescribed for?

  • Colorectal Cancer

    Dabenzole Infusion 100 mg 1 Vial is used in the treatment of cancer that affects the large intestine of the digestive system.

Concerns

Frequently asked questions

  • Onset of action

    The peak effect of this medicine can be observed in 2 hours after intravenous injection.

  • Duration of Effect

    The peak effect of this medicine can be observed in 2 hours after intravenous injection.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendencies were reported.

  • Usage in pregnancy?

    This medicine is not recommended for pregnant women.

  • Usage while breast-feeding?

    This medicine is not recommended in breastfeeding women.

When not to use?

  • Allergy

    Not recommended in patients with known allergy to Dabenzole Infusion 100 mg 1 Vial or other platinum-containing compounds.

  • Severe myelosuppression

    Not recommended in patients with low white blood cell and platelet count.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for pregnant women.

  • Breast-feeding

    This medicine is not recommended in breastfeeding women.

General Warnings
  • Impaired kidney function

    This medicine may cause severe kidney injury. The risk may increase if taken with aminoglycoside antibiotics. Close monitoring of serum creatinine, urea, and sodium levels is necessary.

  • Hearing impairment

    This medicine may cause the hearing problem which is more common in children. Audiometric testing should be performed before initiating the treatment and also before every dose. Any symptoms of the hearing problem should be reported to the doctor.

  • Allergy

    This medicine may cause serious skin reactions. Discontinue the treatment if any symptoms of allergy appear and do not restart.

  • Blood cell count

    This medicine may lower the white blood cells and platelets. Close monitoring of blood cell count is necessary. Do not start the treatment if the cell count is low.

  • Infections

    The chances of occurring infections are more in patients receiving this medicine. Hold the chemotherapy and start with the broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.

  • Lung toxicity

    This medicine may cause rare but fatal lung injury. Inform the doctor if you have any lung disease. Any symptoms of difficulty in breathing, non-productive cough should be reported to the doctor. Discontinue the treatment until the exact cause is identified.

  • Impaired liver function

    This medicine may cause liver injury. The baseline of liver enzymes should be obtained before initiating the therapy. Any signs of elevation in the liver enzymes should be informed to the doctor. Discontinue the treatment until the levels reach to normal.

  • Neuropathy

    This medicine may cause severe nerve damage which may develop within hours of adminstration and resolves within 14 days or may persist for more than 14 days. Any symptoms of tingling or burning sensation of hands and feet should be reported to the doctor.

Dosage

  • Missed Dose

    It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

Interaction with Medicines
  • Clozapine severe
  • Vancomycin moderate
  • Atorvastatin moderate
  • Live vaccines severe
Disease interactions
  • severe

    This medicine should be used with caution in patients with heart diseases due to the increase in the risk of irregular heart rhythm. Monitor the potassium levels, which may exacerbate the condition. Any symptoms of heart palpitation should be reported to the doctor.

  • severe

    This medicine may cause rare but fatal lung injury. Inform the doctor if you have any lung disease. Any symptoms of difficulty in breathing, non-productive cough should be reported to the doctor. Discontinue the treatment until the exact cause is identified.

General Instructions

This medicine is given in multiple cycles. It is important to receive the every scheduled dose and make a note of next scheduled dose. Close monitoring of blood cells counts and kidney function.

Other details

  • Usage does not depend on food timings
  • To be taken as instructed by doctor
  • May cause sleepiness

References

Additional Information>

How to use Dabenzole Infusion 100 mg 1 Vial

For administration by IV inf, the liquid concentrated injection must be diluted in 250 to 500 mL of D5W. Chloride containing solutions must not be used for dilution.
Compatibility: Incompatible with alkaline solutions (e.g. fluorouracil) and chloride-containing solutions. Flush infusion line with D5W prior to and following, administration of concomitant medications via same IV line.
Stability: Store intact vials at room temperature of 25°C (77°F) and under normal lighting; excursions permitted to 15°C-30°C (59°F-86°F). Reconstituted solutions may be stored up to 24 hours at room under refrigeration at 2°C-8°C (36°F-46°F). Diluted solution is stable up to 6 hours at room temperature of 20°C-25°C (68°F-77°F) or up to 24 hours under refrigeration at 2°C-8°C (36°F-46°F).

what are the adverse effects of Dabenzole Infusion 100 mg 1 Vial?

Peripheral sensory neuropathy, pharyngolaryngeal dysaesthesia, anaemia, neutropenia, thrombocytopenia, nausea, diarrhoea, mucositis/stomatitis, alopecia. Raised liver enzymes, allergic reactions, ototoxicity, renal function disturbance, transient loss of visual acuity.

What happens if I miss a dose of Dabenzole Infusion 100 mg 1 Vial?

Adults: Metastatic colorectal cancer: 85 mg/m² every 2 wk by IV infusion over 2-6 hr prior to administration of 5-FU.
Stage III colon cancer: 85 mg/m² every 2 wk for 12 cycles by IV infusion over 2-6 hr prior to administration of 5-FU.
Children: Not recommended.

One of the following licensed pharmacy from the nearest location will deliver Dabenzole Infusion 100 mg 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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