Daunocin Injection 20 mg 1 Vial

 637.00

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 20 mg
Drug Form : Injection
Pack Size : 1 vial
Does this requires a prescription ?Yes

Daunocin Injection contains Daunomycin | belongs to Cytotoxic antibiotic

SKU: pg_5764_8012 Categories: ,

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    How it works

    Daunocin Injection 20 mg 1 Vial blocks a certain enzyme needed for cell division and DNA repair, and it may kill cancer cells

    Side effects

    Major & minor side effects for Daunocin Injection 20 mg 1 Vial

    • Swelling of face, lips, eyelids, tongue, hands and feet
    • Fever
    • Irregular heartbeat
    • Unusual weight gain or loss
    • Tingling of hands or feet
    • Excessive air or gas in stomach
    • Black or tarry stools
    • Dizziness and fainting
    • Dry mouth

    Uses of Daunocin Injection 20 mg 1 Vial

    What is it prescribed for?

    • Skin and Skin Structure Infection

      This medicine is used to treat complicated skin and skin structure infections caused by Staphylococcus aureus, Streptococcus pyogenes, Enterococcus faecalis, etc.

    • Bacteremia

      This medicine is used for the treatment of bacteremia (bacterial infection in the bloodstream) caused by Staphylococci aureus, including bacteremia associated with right-sided infective endocarditis (RIE).

    • Endocarditis

      This medicine is used in the treatment of endocarditis (an infection of the inner lining of the heart) caused by Staphylococci aureus.

    Concerns

    Frequently asked questions

    • Onset of action

      The amount of time required for this medicine to show its action is not clinically established.

    • Duration of Effect

      The amount of time for which this medicine remains active in the body is not clinically established.

    • Safe with Alchohol?

      Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

    • Is it habit forming?

      No habit-forming tendencies were reported.

    • Usage in pregnancy?

      This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

    • Usage while breast-feeding?

      This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

    When not to use?

    • Allergy

      This medicine is not recommended for use if you have a known allergy to Daptomycin or any other inactive ingredients present along with it.

    Warnings

    Warnings for special population
    • Pregnancy

      This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

    • Breast-feeding

      This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

    General Warnings
    • Kidney diseases

      This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

    • Drug-resistance

      Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing benefits and may even cause toxicity. It may also increase the risk of development of bacteria that are drug-resistant.

    • Anaphylaxis

      Use of this medicine may cause anaphylactic reactions such as shock, skin rashes, nausea, vomiting, diarrhea, abdominal cramps, increased heart rate, low blood pressure, itching, fever, chills, bronchospasm, and angioedema in some patients. Appropriate corrective measures, dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

    • Clostridium difficile-associated diarrhea

      Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this medicine in such cases.

    • Use in children

      This medicine is not recommended for use in patients less than 12 months of age since the safety and efficacy of use are not clinically established.

    • Muscle degradation and Rhabdomyolysis

      This medicine may cause muscle breakdown and rhabdomyolysis in some patients, a condition which can be fatal. This may cause symptoms such as muscle pain, severe tiredness, and weakness. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be necessary based on the clinical condition.

    Dosage

    • Missed Dose

      Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

    • Overdose

      Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

    Interactions

    Interaction with Medicines
    • Cholera Vaccine severe
    • Ethinyl Estradiol moderate
    • Atorvastatin moderate
    • Diclofenac moderate
    Disease interactions
    • moderate

      This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

    • This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

    General Instructions

    This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.

    Other details

    • Usage does not depend on food timings
    • To be taken as instructed by doctor
    • May cause sleepiness

    References

    Additional Information>

    How to use Daunocin Injection 20 mg 1 Vial

    IV: Never administer IM or SC. Administer IVP over 1-5 min into the tubing of a rapidly infusing IV solution of D5W or NS; Daunorubicin has also been diluted in 100 mL of D5W or NS and infused over 15-30 min. Extravasation management: Apply ice immediately for 30-60 min; then alternate off/on every 15 min for 1 day. Topical cooling may be achieved using ice packs or cooling pad with circulating ice water. Cooling of site for 24 hours as tolerated by the patient. Elevate and rest extremity 24-48 hours, then resume normal activity as tolerated. Application of cold inhibits vesicant’s cytotoxicity. Application of heat or sodium bicarbonate can be harmful and is contraindicated. If pain, erythema and/or swelling persist beyond 48 hours, refer patient immediately to plastic surgeon for consultation and possible debridement.
    Reconstitution: Dilute vials with 4 mL SWFI for a final concentration of 5 mg/mL.
    Compatibility: Stable in D5W, LR, NS, SWFI.

    What happens if I miss a dose of Daunocin Injection 20 mg 1 Vial?

    Adults: 0.8 mg/kg IV and continue with a maintenance dose of 0.8-1 mg/kg. Max 25 mg/kg. Children: Initial dose of 1 mg/kg of daunomycin by IV daily for 4-5 days, max 25 mg/kg. See literature.

    One of the following licensed pharmacy from the nearest location will deliver Daunocin Injection 20 mg 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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