MBBS
Denla XR tablet 100 mg 14’s
- Does this requires a prescription ? Yes
- Generic Name: Desvenlafaxine
- Manufactured by : Semos Pharmaceuticals (PVT) LTD.
- Drug Strength : 100 mg
- Drug Form : XR tablet
- Pack Size : 14s
- Product SKU : pu_pg_5953_8309
Denla XR tablet contains Desvenlafaxine | belongs to Serotonin and noradrenaline reuptake inhibitor
Alternate brands of Denla XR tablet 100 mg 14’s
Brand Name | Price | Savings |
---|---|---|
Lafaxine tablet ER 100 mg 14’s | ₨ 375.37 | You can save 86.3 |
Lafaxine tablet ER 50 mg 14’s | ₨ 280.51 | You can save 181.16 |
Denla XR tablet 50 mg 14’s | ₨ 344.98 | You can save 116.69 |
How it works
Denla XR tablet 100 mg 14’s works by increasing the amounts of serotonin and norepinephrine, natural substances in the brain that help maintain mental balance.
Side effects
Major & minor side effects for Denla XR tablet 100 mg 14’s
- Suicidal thinking and behaviour severe
- Serotonin syndrome (agitation, hallucinations, seizures, nausea) severe
- Irregular heartbeat severe
- Shaking of the hands or feet
- Dizziness when getting up suddenly from a sitting position
- Chills or cold sweats severe
- Blurred vision rare
- Nausea and Vomiting
- Dry mouth
- Constipation
- Muscle stiffness
- Decrease in libido
- Difficulty in passing urine
- Rapid weight gain/loss rare
- Photosensitivity rare
- Ringing or buzzing in the ears
Uses of Denla XR tablet 100 mg 14’s
What is it prescribed for?
-
Depression
This medicine is used to treat depression and symptoms associated with major depressive disorder.
Concerns
Frequently asked questions
-
Onset of action
The effect of this medicine is cumulative and takes 7-8 weeks to show in most cases.
-
Duration of Effect
The time duration for which this medicine remains effective is 20-25 days.
-
Safe with Alchohol?
Avoid or limit the uptake of alcohol while using this medicine. It is advised to refrain from driving vehicles and operating heavy machinery while using this medicine.
-
Is it habit forming?
No habit forming tendencies were reported.
-
Usage in pregnancy?
This medicine should be used by pregnant women only when the potential benefits outweigh the risks involved. Consult your doctor before using this medicine.
-
Usage while breast-feeding?
This medicine is not recommended for use by breastfeeding women. It is recommended to discontinue breastfeeding before starting the treatment with this medicine. Consult your doctor before using this medicine.
When not to use?
-
Allergy
This medicine is not recommended for use if you have a known history of allergy to Denla XR tablet 100 mg 14’s or any other component present in the medicine.
-
Monoamine oxidase inhibitors (MAOI)
This medicine is not recommended for use while a MAOI (Rasagiline/Selegiline/methylene blue etc.) is being consumed. This medicine should be consumed at least 14 days after stopping the use of MAOI medicines.
Warnings
-
Pregnancy
This medicine should be used by pregnant women only when the potential benefits outweigh the risks involved. Consult your doctor before using this medicine.
-
Breast-feeding
This medicine is not recommended for use by breastfeeding women. It is recommended to discontinue breastfeeding before starting the treatment with this medicine. Consult your doctor before using this medicine.
-
Suicidal thinking and behaviour
Use of this medicine may cause suicidal thought and change the behavior of the user. This risk is increasingly high in young patients. It is recommended to screen the patient for such behavior before starting the treatment. Any change in behavior and thought process after taking this medicine should be reported to the doctor immediately.
-
Serotonin syndrome
Use of this medicine with other medicines to treat depression may cause nausea, agitation, seizures and hallucinations (symptoms of serotonin syndrome)
-
Neuroleptic malignant syndrome
Use of this medicine may cause Neuroleptic malignant syndrome characterized by high fever, muscle stiffness, extreme changes in blood pressure, excessive sweating and salivation. The use of this medicine should be stopped as soon as these side effects are experienced.
-
Hypertension
Use of this medicine is associated with a sharp increase in blood pressure levels. It is recommended to control hypertension using appropriate medicines before starting the treatment with Denla XR tablet 100 mg 14’s .
-
Bleeding disorders
Use of this medicine may cause unusual bleeding and bruising and hence should be used with caution in patients suffering from bleeding disorders. Use of medicines that are known to cause gastrointestinal bleeding, (example: aspirin, paracetamol, ibuprofen etc), should be avoided while taking Denla XR tablet 100 mg 14’s .
-
Glaucoma
This medicine should be used with caution in patients suffering from angle closure glaucoma. The symptoms of this disease may worsen upon using Denla XR tablet 100 mg 14’s and hence caution is advised.
-
Seizure disorder
Use of this medicine may cause seizures and hence should be used with caution in patients suffering from epilepsy.
-
Manic episodes
Use of this medicine may cause agitation and aggressive behavior in some patients. The patient should be screened for bipolar disorder before starting the treatment course with this medicine.
-
Heart disease
This medicine should be used with caution in patients suffering from a heart or blood vessel disorder.
-
Hyponatremia
This medicine may decrease the sodium levels in the body and hence should be used with caution in patients taking diuretic medicines.
-
Bone fractures
Use of this medicine has been associated with an increase in the incidence of bone fractures. Report any incidence of bone pain to the doctor while taking Denla XR tablet 100 mg 14’s .
-
Drowsiness and cognitive impairment
Use of this medicine has been associated with drowsiness and impairment of cognition. It is advised to refrain from driving vehicles or operating heavy machinery while taking this medicine.
-
Sexual dysfunction
Use of this medicine may cause sexual dysfunction. These dysfunctions may include a decrease in libido, erectile disorders, or unusual orgasm.
-
Withdrawal symptoms
Use of this medicine should not be discontinued abruptly. It is advised to gradually reduce the dose of this medicine.
-
Monoamine oxidase inhibitor drugs
This medicine should be used at least 14 days after stopping the use of MOAI drugs. Use of Denla XR tablet 100 mg 14’s should stop at least 7 days before using the other medicine.
-
Pediatric use
This medicine is not recommended for use in patients aged below 18 years.
-
Use in elderly
This medicine should be used with caution in elderly patients as the risk of adverse effects is significantly high.
Dosage
-
Missed Dose
Take the missed dose as soon as you remember. If the next scheduled dose is 4 hours away, then the missed dose should be skipped.
-
Overdose
Contact a doctor immediately if an overdose with this medicine is suspected. Symptoms of an overdose may include agitation, hallucinations, convulsions, and nausea.
Interactions
Interaction with Medicines- Linezolid severe
- Lithium severe
- Sertraline severe
- Warfarin moderate
- Aspirin moderate
- Methylene blue severe
- Indinavir moderate
- Sumatriptan severe
-
severe
This medicine should be used with caution in patients with an impaired kidney functions. Suitable dose adjustments should be made based on the serum creatinine levels for moderate to severe impairment.
-
moderate
This medicine should be used with caution in patients having narrow-angle glaucoma. The symptoms of the disease might worsen if this medicine is used in such patients.
-
moderate
This medicine may cause an increase in the blood pressure levels and hence should be used with caution in patients with hypertension. The blood pressure level should be constantly monitored before and during the course of treatment.
General Instructions
Take Denla XR tablet 100 mg 14’s as instructed by the doctor. Do not use in smaller or larger than the recommended dose. The dose is likely to change over time based on your response and hence adherence to the changes is a must. Do not stop the use of this medicine abruptly.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- May cause sleepiness
References
- medlineplus.gov - Desvenlafaxine [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a608022.html [cited 28/7/2020]. 2020
what are the adverse effects of Denla XR tablet 100 mg 14’s?
Nausea, dizziness, sleeplessness, excessive sweating, constipation, drowsiness, decreased appetite, anxiety and specific male sexual function disorders. Palpitations, fast heart rate and high blood pressure. Dry mouth, diarrhoea, constipation and vomiting. Fatigue, chills, uneasiness and weakness. Decreased appetite and weight. Headache, tremor, tingling, disturbance in attention, nervousness, irritability and abnormal dreams. Urinary hesitation. Yawning and nose bleed. Excessive sweating and rash. Blurred vision, dilation of the pupil, ringing in the ear and loss of taste. Muscle stiffness. Hot flush and severe allergic reactions.
What happens if I miss a dose of Denla XR tablet 100 mg 14’s?
Adults: 50 mg once daily. Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Denla XR tablet 100 mg 14’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
There are no questions yet. Be the first to ask a question about this product.
Related products
Products listed on medicalstore.com.pk are 100% genuine and sourced from licensed pharmacies.
We work hard to bring you unimaginable discounts without compromising on quality.
We uses SSL (standard security technology) to ensure data privacy of all our customers.
2 reviews for Denla XR tablet 100 mg 14’s
Tariq latif –
Tariq latif submitted 4 stars.
Anonymous (verified owner) –
submitted 5 stars.