Depo-Medrol Injection 40 mg 1 Ampx2 mL

How to use Depo-Medrol Injection 40 mg 1 Ampx2 mL

Do not use intrathecally. Intra-articular: A sterile 20- to 24-gauge needle (on a dry syringe) is quickly inserted into the synovial cavity. Procaine infiltration is elective. The aspiration of only a few drops of joint fluid proves the joint space has been entered by the needle. The inj site for each joint is determined by that location where the synovial cavity is most superficial & most free of large vessels & nerves. With the needle in place, the aspirating syringe is removed and replaced by a second syringe containing the desired amount of methylprednisolone. The plunger is then pulled outward slightly to aspirate synovial fluid and to make sure the needle is still in the synovial space after inj, the joint is moved gentle a few times to aid mixing of the synovial fluid and the suspension. The site is covered with a small dressing. Intralesional: Make multiple small injections into the area of the lesion whenever possible. Care should be taken to avoid inj of the sufficient material to cause blanching because this may be followed by a small slough. IM: Inj IM form deep into gluteal muscle. Avoid inj into the deltoid muscle. Take precautions against inj or leakage into the dermis.
Compatibility: Do not mix with other solns. Stable in D5W, NS.
Y-site administration:
Drug to Drug IV Compatibility: Acyclovir, amikacin, amiodarone, aztreonam, bumetanide, cephazolin, cefepime, ceftriaxone, cimetidine, dexamethasone, dobutamine, dopamine, enalapril, epinephrine, famotidine, fentanyl, fluconazole, furosemide, gentamicin, heparin, hydromorphone, imipenem, insulin regular, labetalol, levofloxacin, linezolid, metoclopramide, metronidazole, midazolam, milrinone, morphine, nitroglycerin, nitroprusside, norepinephrine, phenylephrine, piperacillin/tazobactam, ranitidine, tobramycin, vancomycin, vasopressin.
Stability: Store at 20°C-25°C. Do not autoclave when it is desirable to sterilize the outside of the vial.

what are the adverse effects of Depo-Medrol Injection 40 mg 1 Ampx2 mL?

Endocrine irregularities including menstrual problems, Cushingoid state, adrenal suppression, growth suppression in children. Increased susceptibility to infection, increased severity of infection. Fluid/electrolyte disturbance, hypertension, negative protein, nitrogen and calcium balance. Myopathy, tendon rupture, osteoporosis, osteonecrosis and fractures. Impaired wound healing, sweating, hirsutism, striae, telangiectasia, acne. GI disturbance, peptic ulceration, acute pancreatitis, candidiasis. Psychiatric effects, neurological effects, insomnia. Diabetes, impaired glucose tolerance, weight gain, increased appetite. Ocular disturbances including cataracts, raised intraocular pressure, optic nerve damage, corneal changes, glaucoma. Thromboembolism, leukocytosis.

What happens if I miss a dose of Depo-Medrol Injection 40 mg 1 Ampx2 mL?

Adults: Only sodium succinate may be given IV; methylprednisolone sodium succinate is highly soluble and has a rapid effect by IM and IV routes. Methylprednisolone acetate has a low solubility and has a sustained IM effect.
Anti-inflammatory or immunosuppressive: IM: 10-80 mg every 1-2 wk.
Arthritis: Intra-articular: Administer every 1-5 wk. Large joints (e.g. knee, ankle): 20-80 mg; Medium joints (e.g. elbow, wrist): 10-40 mg; Small joints: 4-10 mg.
Dermatitis: Acute severe: IM: 80-120 mg as a single dose. Chronic: IM: 40-120 mg every 5-10 days.
Dermatologic conditions (e.g. keloids, lichen planus): Intralesional: 20-60 mg.

One of the following licensed pharmacy from the nearest location will deliver Depo-Medrol Injection 40 mg 1 Ampx2 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.