₨ 49.79
MBBS
Dihydan tablet 100 mg 100’s
- Does this requires a prescription ? Yes
- Generic Name: Phenytoin
- Manufactured by : French Pharmaceutical Group
- Drug Strength : 100 mg
- Drug Form : Tablet
- Pack Size : 100s
- Product SKU : pg_6499_8991
Dihydan tablet contains Phenytoin | belongs to Hydantoin
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How it works
Dihydan tablet 100 mg 100’s works by decreasing abnormal electrical activity in the brain.
Uses of Dihydan tablet 100 mg 100’s
What is it prescribed for?
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Seizures
Dihydan tablet 100 mg 100’s is used in the treatment of seizures which is a brain disorder characterized by uncontrolled jerking movements and loss of consciousness.
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Status Epilepticus
Dihydan tablet 100 mg 100’s is used in the treatment of status epilepticus which is a condition in which seizures present for a long time or a seizure follows immediately after another.
Concerns
Frequently asked questions
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Onset of action
The peak effect of this medicine can be observed in 1.5 to 3 hours for an immediate release tablet and 4 to 12 hours for an extended release tablet.
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Duration of Effect
The effect of this medicine lasts for an average duration of 2 to 3 days for an oral dose and 1 to 2 days for an intravenous dose.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit forming tendency has been reported
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Usage in pregnancy?
This medicine is not recommended for pregnant women.
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Usage while breast-feeding?
This medicine is known to be excreted in the breastmilk. It is not recommended in breastfeeding women unless absolutely necessary.
When not to use?
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Allergy
Not recommended in the patients with known allergy to Dihydan tablet 100 mg 100’s .
Warnings
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Pregnancy
This medicine is not recommended for pregnant women.
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Breast-feeding
This medicine is known to be excreted in the breastmilk. It is not recommended in breastfeeding women unless absolutely necessary.
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Withdrawal symptoms
Do not stop suddenly taking this medicine without informing the doctor. It may precipitate the status epilepticus in patients with known history of epilepsy.
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Suicidal behavior
This medicine should be used with caution in patients with known history of depression. It may increase the risk of suicidal thoughts. Educate the patient's caretakers about these symptoms. Inform the doctor if the symptoms persist.
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Skin reactions
This medicine may cause serious skin reactions like toxic epidermal necrolysis and Stevens-Johnson syndrome. Seek immediate medical treatment if any symptoms of skin reactions appear
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Impaired liver function
This medicine should be used with caution in patients with the liver injury. Close monitoring of liver function tests is necessary. Discontinue the treatment if the symptoms persist.
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Effects on bone
This medicine is known to decrease the bone density and may increase the risk of osteoporosis and osteomalacia. Inform the doctor if you have any bone disorder. Close monitoring of Vit-D levels and radiological findings is necessary.
Dosage
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Missed Dose
Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
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Overdose
Seek emergency medical treatment or contact the doctor if any symptoms of the overdose like uncontrolled body movements, slurred speech appear.
Interactions
Interaction with Medicines- Metoclopramide moderate
- Voriconazole severe
- Warfarin moderate
- Ethinyl Estradiol severe
General Instructions
Take Dihydan tablet 100 mg 100’s nytoin as advised by your doctor. Do not take this medicine with calcium supplements or antacids due to the decrease in the absorption. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting the doctor as it may cause seizures.
References
- medlineplus.gov - Phenytoin [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a682022.html [cited 14/7/2020]. 2020
How to use Dihydan tablet 100 mg 100’s
Administered by direct IV injection into a large vein. The rate of IV injection should not exceed 50 mg/min in adults or 1-3 mg/kg/min in neonates. Following IV injection, NaCl 0.9% should be injected through the same needle or catheter to reduce irritation.
Compatibility: Stable in dextrose 5%, NaCl 0.9%, fat emulsion 10% IV.
Stability: Phenytoin is stable as long as it remains free of haziness and precipitation. If refrigerated or frozen, a precipitate may form, but it dissolves on standing at room temperature.
what are the adverse effects of Dihydan tablet 100 mg 100’s?
Gastric distress, sleeplessness, unsteadiness. Allergic reactions. Gingival hypertrophy, hirsutism and motor activity in young patients. Blood dyscrasias, lymphadenopathy and nystagmus. Withdraw if skin rash occurs. IV injection may cause cardiovascular and CNS depression (particularly if injection too rapid) with arrhythmias, hypotension and cardiovascular collapse; alterations in respiratory function (including respiratory arrest); injection site reactions.
What happens if I miss a dose of Dihydan tablet 100 mg 100’s?
Adults: ORAL: 100 mg two or four times before meals with max total of 600 mg daily. Titrate: Every 7-10 days. May give once daily if controlled on 300 mg/day.
INJECTION: By slow IV injection or infusion (with blood pressure and ECG monitoring). Status epilepticus: 18 mg/kg at a rate not exceeding 50 mg per min, as a loading dose; maintenance doses of about 100 mg should be given thereafter at intervals of every 6-8 hr, monitored by measurement of plasma concentrations; rate and dose reduced according to weight.
Children: Tonic-clonic seizures, focal seizures: IV INJECTION (over 20-30 minutes) or ORAL: Neonate, initial loading dose by slow IV injection (section 4.8.2) 18 mg/kg then by mouth 2.5-5 mg/kg twice daily adjusted according to response and plasma-phenytoin concentration (usual max 7.5 mg/kg twice daily). 1 mth-12 yr, Oral initially 1.5-2.5 mg/kg twice daily, then adjusted according to response and plasma-phenytoin concentration to 2.5-5 mg/kg twice daily (usual max 7.5 mg/kg twice daily or 300 mg daily); 12-18 yr, Oral initially 75-150 mg twice daily then adjusted according to response and plasma phenytoin concentration to 150-200 mg twice daily (usual max 300 mg twice daily).
Status epilepticus, acute symptomatic seizures associated with head trauma or neurosurgery: Slow IV injection or infusion: Neonate, initially 20 mg/kg as a loading dose then 2.5-5 mg/kg twice daily; 1 mth-12 yr, initially 20 mg/kg as a loading dose then 2.5-5 mg/kg twice daily; 12-18 yr, initially 20 mg/kg as a loading dose then up to 100 mg 3-4 times daily.
One of the following licensed pharmacy from the nearest location will deliver Dihydan tablet 100 mg 100’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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