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Dinetac tablet 150 mg 10's

Dinetac tablet contains Ranitidine | belongs to H2 blocker

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How it works

This medicine works by reducing the amount of acid produced in the stomach.

Side effects

Major & minor side effects for Dinetac tablet 150 mg 10’s

  • Headache
  • Dizziness severe
  • Nausea or vomiting
  • Diarrhea severe
  • Stomach pain
  • Mental confusion severe
  • Muscle pain
  • Difficulty in breathing severe
  • Gynecomastia severe

Uses of Dinetac tablet 150 mg 10’s

What is it prescribed for?

  • Duodenal Ulcer

    This medicine is used for the short-term treatment of ulcers of the first part of the small intestine (duodenum). It can also be used to prevent recurrence of ulcer in some patients.

  • Gastric Ulcer

    This medicine is used for the short-term treatment of stomach ulcers that are benign. It is also used as a maintenance therapy after the ulcers have healed.

  • Gastroesophagal Reflux Disease

    This medicine is used for the treatment of a condition where the acid produced in the stomach causes irritation in the food pipe.

  • Erosive Esophagitis

    This medicine is used for the treatment of a condition where the food pipe is eroded due to prolonged acid reflux from the stomach.

  • Zollinger-Ellison Syndrome

    This medicine is used to relieve the symptoms of this rare condition where the acid secretion in the stomach is abnormally high.

  • Hypersecretory Condition

    This medicine is used to prevent and treat conditions where the amount of acid secreted in the stomach is abnormally high.

Concerns

Frequently asked questions

  • Onset of action

    The effect of this medicine can be observed after an hour of oral or intravenous administration.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 4-6 hours.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit-forming tendencies were reported.

  • Usage in pregnancy?

    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

When not to use?

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to Dinetac tablet 150 mg 10’s or any other inactive ingredients present along with it.

  • Porphyria

    This medicine is not recommended for use in patients with porphyria, a disorder that results from a buildup of porphyrin in the body.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

  • Breast-feeding

    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Warnings

Warnings for special population
  • Pneumonia

    Use of this medicine may increase the risk of developing pneumonia. Symptoms like chest pain. fever. difficulty in breathing and presence of green or yellow mucus with a cough is to be reported to the doctor on priority.

  • Chronic heartburn

    If you have a chronic heartburn (more than 3 months) or your heartburn continues or worsens, consult your doctor immediately since this may be a sign of a more serious condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in such cases based on the clinical condition.

  • Vitamin deficiency

    This medicine can interfere with the absorption of Vitamin B12 upon prolonged usage. Your doctor may prescribe appropriate supplementation or may suggest appropriate changes in your diet based on your clinical condition.

  • Kidney disease

    This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Appropriate dose adjustments and close monitoring of renal function may be required based on the clinical condition.

  • Phenylketonuria

    Some formulations of this medicine may contain phenylalanine. Such formulations should be used with extreme caution in patients with Phenylketonuria who must restrict their intake of phenylalanine. Replacement with a suitable alternative may be required based on the clinical condition.

  • Use of nicotine

    Use of nicotine is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.

  • Pediatric use

    This medicine should be used with extreme caution in children due to the increased risk of severe adverse effects. All the risks and benefits should be discussed with the doctor before using this medicine.

Dosage

  • Missed Dose

    Oral forms: If a dose of this medicine is missed, take the dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose and take the next dose. Do not double the dose to make up for the missed one. Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

  • Overdose

    Oral forms: Seek emergency medical treatment or contact the doctor in case of an overdose. Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions

Interaction with Medicines
  • Ketoconazole moderate
  • Loperamide severe
  • Metformin moderate
  • Atazanavir severe
  • Dasatinib severe
  • Pazopanib severe
Disease interactions
  • severe

    This medicine is not recommended for use in patients with gastrointestinal bleeding since it may worsen the patient's condition. Replacement with a suitable alternative should be done under your doctor's supervision.

  • moderate

    This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Appropriate dose adjustments and close monitoring of liver function may be required based on the clinical condition.

General Instructions

Oral forms: Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor. Injection: This medicine should be administered only by a qualified healthcare professional in the clinical or hospital setting. Carefully follow all the instructions given by your doctor.

Other details

  • To be taken before food
  • To be taken as instructed by doctor
  • Does not cause sleepiness

References

How to use Dinetac tablet 150 mg 10’s

IM: No dilution is needed. IV: Intermittent bolus: Dilute vials to 2.5 mg/ mL; infuse at 4 mL/min (5 min). Intermittent infusion: Dilute vials to 0.5 mg/ mL; infuse at 5-7 mL/min (15-20 min). Continuous IV infusion: Administer at 6.25 mg/hr and titrate dosage based on gastric pH by continuous infusion over 24 hours. Solutions are stable for 48 hours at room temperature. Vials can be mixed with NS or D5W.
Compatibility: Stable in D5 ½ NS, D5W, D10W, fat emulsion 10%, LR, NS, sodium bicarbonate 5%.
Y-site administration:
Drug to Drug IV Compatibility: Acyclovir, amiodarone, aztreonam, cephazolin, cefepime, ciprofloxacin, cisatracurium, digoxin, diltiazem, dobutamine, dopamine, enalapril, epinephrine, esmolol, fentanyl, fluconazole, furosemide, gentamicin, heparin, labetalol, linezolid, lorazepam, meropenem, methylprednisolone, metoclopramide, midazolam, milrinone, morphine, nitroglycerin, nitroprusside, norepinephrine, ondansetron, piperacillin/tazobactam, propofol, vancomycin, vecuronium.
Drug to Drug IV Incompatibility: Amphotericin B cholesteryl sulphate complex, hetastarch, insulin regular.
In syringe: Incompatible with hydroxyzine, methotrimeprazine, midazolam, pentobarbital, phenobarbital.
When admixed: Incompatible with amphotericin B, atracurium, cefamandole, cephazolin, cefoxitin, ceftazidime, cefuroxime, ethacrynate, metaraminol, phytonadione.
Stability: Store vials between 4°C-30°C. Protect from light.

UNLICENSED USE
Children: Reflux oesophagitis, benign gastric and duodenal ulcer, prophylaxis of stress ulcer and other conditions where gastric acid reduction is beneficial: ORAL: Neonate, 2 mg/kg daily, max 3 mg/kg; 1-6 mth, 1 mg/kg daily, max 3 mg/kg; 6 mth-3 yr, 2-4 mg/kg twice daily. INJECTION: Neonates: By slow IV injection 0.5-1 mg/kg every 6-8 hr. 1-6 mth: By slow IV injection, 1 mg/kg (max 50 mg) every 6-8 hr or by intermittent infusion, 1 mg/kg (max 50 mg) every 6-8 hr at a rate of 25 mg/hr.
Prophylaxis of stress ulceration: Adults and Children: Over 12 yr, by slow IV injection over at least 2 minutes, 50 mg diluted to 20 mL, every 8 hr. May be changed or orally 150 mg twice daily when oral feeding commences.

what are the adverse effects of Dinetac tablet 150 mg 10’s

Headache, dizziness, changes in liver function. Rarely hepatitis, thrombocytopenia, leucopenia, agranulocytosis, pancytopenia, hypersensitivity, confusion, breast symptoms in men, reversible impotence, rash, bradycardia, pancreatitis.

What is the dose of Dinetac tablet 150 mg 10’s

Adults: ORAL: Duodenal and gastric ulcer: 150 mg twice daily or 300 mg at bedtime for four wk or 300 mg twice daily; maintenance, 150 mg at bedtime.
DU with H. pylori: 300 mg at bedtime for 4 wk plus amoxicillin 750 mg three times daily and metronidazole 500 mg three times daily for 2 wk.
Prevention of NSAID induced duodenal ulcer: 150 mg twice daily.
Reflux oesophagitis: 150 mg twice daily or 300 mg at bedtime for up to 12 wk. If moderate to severe, 150 mg four times daily for up to 12 wk.
Prevention of heartburn: 75 mg 30-60 minutes before eating food or drinking beverages which caused heartburn. Max 150 mg/day. Do not use for more than 14 days.
Pathological hyper secretory conditions: 150 mg twice daily, adjust as necessary, doses up to 6 gm/day have been used.
GERD: 150 mg twice daily.
Erosive oesophagitis: Treatment, 150 mg four times daily, maintenance 150 mg twice daily.
Adults: INJECTION: IM: 50 mg every 6-8 hr. IV: By slow IV injection, 50 mg diluted to 20 mL and administered over at least 2 minutes. 50 mg may be repeated every 6-8 hr. May be given as an intermittent infusion at a rate of 25 mg/hr over a period of 15-20 minutes. May be given by continuous IV infusion, initial 1 mg/kg/hr, titrate dose based on gastric pH.
Children: Reflux oesophagitis, benign gastric and duodenal ulceration, prophylaxis of stress ulceration, other conditions where gastric acid reduction is beneficial: ORAL: 3-12 yr 2-4 mg/kg (max. 150 mg) twice daily; increased up to 5 mg/kg (max. 300 mg) twice daily in severe gastro-oesophageal reflux disease; 12-18 yr, 150 mg twice daily or 300 mg at night; increased if necessary, to 300 mg twice daily or 150 mg 4 times daily for up to 12 wk in moderate to severe gastro-oesophageal reflux disease. In fat malabsorption syndrome, give 1-2 hr before food to enhance effects of pancreatic enzyme replacement. INJECTION: By slow IV injection: 6 mth-18 yr, 1 mg/kg, max 50 mg, every 6-8 hr. May be given as an intermittent infusion at a rate of 25 mg/hr.

One of the following licensed pharmacy from the nearest location will deliver Dinetac tablet 150 mg 10’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

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