₨ 529.71
MBBS
Duranim tablet 30 mg 3×10’s
- Does this requires a prescription ? Yes
- Generic Name: Nimodipine
- Manufactured by : Pearl
- Drug Strength : 30 mg
- Drug Form : Tablet
- Pack Size : 3x10s
- Product SKU : pg_7013_9632
Duranim tablet contains Nimodipine | belongs to Calcium antagonist
Alternate brands of Duranim tablet 30 mg 3×10’s
| Brand Name | Price | Savings |
|---|---|---|
| Nortolan tablet 30 mg 30’s | ₨ 445.00 | You can save 84.71 |
| Nimotop Infusion 10 mg 1 Vialx50 mL | ₨ 965.14 | You will pay -435.43 more |
| Nimotop tablet 30 mg 3×10’s | ₨ 879.59 | You will pay -349.88 more |
| Nimotin tablet 30 mg 30’s | ₨ 450.00 | You can save 79.71 |
| Nimopro tablet 30 mg 30’s | ₨ 450.00 | You can save 79.71 |
How it works
Duranim tablet 30 mg 3×10’s work by relaxing narrowed blood vessels in the brain near the area of bleeding so blood can flow more easily. This effect reduces brain damage.
Side effects
Major & minor side effects for Duranim tablet 30 mg 3×10’s
- Rash
- Headache
- Fast heartbeat
- Low blood pressure
- Nausea
- Chest tightness
- Confusion
- Unusual tiredness or weakness
- Sweating
- Dizziness
- Diarrhea
Uses of Duranim tablet 30 mg 3×10’s
What is it prescribed for?
-
Subarachnoid hemorrhage
This medicine is used in the treatment of subarachnoid hemorrhage, which is a life-threatening condition that occurs due to the rupture of blood vessel in the brain causing bleeding in the space surrounding the brain.
Concerns
Frequently asked questions
-
Onset of action
The amount of time required for this medicine to show its action is not clinically established.
-
Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.
-
Safe with Alchohol?
Consumption of alcohol is not recommended while receiving this medicine as it may increase the risk of adverse effects like dizziness, fainting, lightheadedness, headache, etc. Avoid performing activities that require high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
-
Is it habit forming?
No habit-forming tendencies were reported.
-
Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.
-
Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
When not to use?
-
Allergy
This medicine is not recommended for use in patients with a known allergy to Duranim tablet 30 mg 3×10’s or any other inactive ingredients present along with it.
-
Myocardial infarction/Unstable Angina
This medicine is not recommended for use in patients with myocardial infarction or an episode of unstable angina within one month due to the increased risk of worsening of the patient's condition.
Warnings
-
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.
-
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
-
Hypotension
This medicine should be used with caution due to a risk of hypotension and syncope. This risk is especially higher in patients suffering from cardiovascular and cerebrovascular diseases. Appropriate dose adjustments and close monitoring of blood pressure are necessary for such patients.
-
Congestive heart failure
This medicine should be used with caution in patients with congestive heart failure since it may worsen the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
-
Liver impairment
This medicine should be used with caution in patients with liver disease due to the increased risk of worsening of the patient's condition. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.
-
Use in children
This medicine is not recommended for use in children below 18 years of age since the safety and efficacy of use are not clinically established.
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Kidney impairment
This medicine should be used with caution in patients with kidney disease due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.
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Driving or Operating machinery
Use of this medicine may cause dizziness, fatigue, weakness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.
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Multivitamin with minerals
Use of Nimodip Tablet along with multivitamin with minerals may alter the desired effects of Nimodip Tablet. Close monitoring of blood pressure levels or appropriate dose adjustments may be required based on the clinical condition of the patient.
Dosage
-
Missed Dose
Oral form: Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose. Parenteral form: Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of a missed dose is very less.
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Overdose
Oral form: Seek emergency medical treatment or contact the doctor in case of an overdose. Parenteral form: Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
Interactions
Interaction with Medicines- Atazanavir severe
- Fosphenytoin severe
- Tizanidine severe
- Carbamazepine severe
- Clarithromycin severe
- Rifampicin severe
-
severe
This medicine is not recommended for use in patients suffering from low blood pressure or cardiogenic shock, since it may worsen the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
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severe
This medicine should be used with extreme caution in patients with liver disease due to the increased risk of adverse effects. Regular monitoring of liver function tests is required while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
-
severe
This medicine should be used with extreme caution in patients with coronary artery disease due to the increased risk of adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
-
Consumption of grapefruit or grapefruit juice is not recommended while receiving this medicine. Symptoms like dizziness, headache, swelling of hands and feet should be reported to the doctor on priority.
General Instructions
Consumption of grapefruit or grapefruit juice is not recommended while receiving this medicine. Symptoms like dizziness, headache, swelling of hands and feet should be reported to the doctor on priority.
Other details
- To be taken on an empty stomach
- To be taken as instructed by doctor
- Effect on sleep is not established
References
- webmd.com - Nimodipine [Internet]. Available from: https://www.webmd.com/drugs/2/drug-10951/nimodipine-oral/details [cited 8/7/2020].
How to use Duranim tablet 30 mg 3×10’s
Via drip tubing in D5W or NS or Compound sodium lactate. Not to be added to infusion container, administer via an infusion pump through a Y-piece into a central catheter.
Compatibility: Incompatible with polyvinyl chloride giving sets or containers.
Stability: Nimodipine infusion solution must not be mixed with other drugs. It is advisable to continue administration of nimodipine infusion solution during anesthesia, surgery and angiography. Protect infusion from light.
UNLICENSED USE
Children: INJECTION: Treatment of vasospasm following subarachnoid haemorrhage under specialist advice only: IV infusion: 1 mth-12 yr, initially 15 mcg/kg/hr (max 500 mcg/hr) or initially 7.5 mcg/kg/hr if blood pressure unstable; increase after 2 hr to 30 mcg/kg/hr (max 2 mg/hr) if no severe decrease in blood pressure; continue for at least 5 days (max 14 days); 12-18 yr, initially 500 mcg/hr (up to 1 mg/hr if body-weight over 70 kg and blood pressure stable), increase after 2 hr to 1-2 mg/hr if no severe fall in blood pressure; continue for at least 5 days (max 14 days).
ORAL: Prevention of vasospasm following subarachnoid haemorrhage: 1 mth-18 yr, 0.9-1.2 mg/kg (max 60 mg) 6 times daily, starting within 4 days of haemorrhage and continued for 21 days.
what are the adverse effects of Duranim tablet 30 mg 3×10’s?
Hypotension, flushing, headache, changes in heart rate, GI upset. Transient rise in liver enzymes may occur with infusion. Allergic reactions.
What happens if I miss a dose of Duranim tablet 30 mg 3×10’s?
Adults: ORAL: 2 tab four hrly starting within 4 days of subarachnoid haemorrhage and continue for 21 days.
INFUSION: 1 mg/hr by IV infusion for first 2 hr, then 2 mg/hr for minimum 5 days, max 14 days. Patients weighing under 70 kg or with unstable BP, start on 0.5 mg/hr.
Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Duranim tablet 30 mg 3×10’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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