MBBS
ENDOXAN 50mg Tablet 50s
- Does this requires a prescription ? Yes
- Generic Name: Cyclophosphamide:50mg
- Manufactured by : AGP Limited
- Drug Strength : 50mg
- Drug Form : Tablet
- Pack Size : 50s
- Product SKU : dis_20394
Cyclophosphamide:50mg | Cytotoxic (anti-neoplastic) drugs
Manufactured / Marketed By : AGP
Product Form : Tablet
Pack Size : 50s
Ingredients : Cyclophosphamide:50mg
Generic Category : Cytotoxic (anti-neoplastic) drugs
How it works
ENDOXAN 50mg Tablet 50s works by slowing or stopping the growth of cancer cells in your body. When ENDOXAN 50mg Tablet 50s is used to treat nephrotic syndrome, it works by suppressing your body's immune system.
Side effects
Major & minor side effects for ENDOXAN 50mg Tablet 50s
- Black or tarry stools
- Dizziness
- Hair loss
- Fever and chills
- Weakness
- Loss of appetite
- Nausea and Vomiting
- Diarrhea
- Headache
- Increased sweating
- Skin rash
Uses of ENDOXAN 50mg Tablet 50s
What is it prescribed for?
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Malignant cancers
This medicine is used for the treatment of different types of malignant cancers such as multiple myeloma (cancer that affects plasma cells), certain types of leukemia (blood cancer), including chronic lymphocytic leukemia, acute myeloid leukemia, acute lymphoblastic leukemia, and acute myelogenous leukemia, Hodgkin's lymphoma and non-Hodgkin's lymphoma (types of cancer that affects certain cells called lymphocytes of the lymphatic system), ovarian cancer (cancer that affects the female reproductive system), breast cancer, retinoblastoma (eye cancer), etc.
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Nephrotic Syndrome
This medicine is used to treat a kidney disease called nephrotic syndrome in pediatric patients who have not responded adequately to steroid treatments or if the steroids produce intolerable side effects.
Concerns
Frequently asked questions
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Onset of action
The effect of this medicine can be observed within 2 to 3 hours.
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Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit forming tendency has been reported.
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women.
When not to use?
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Allergy
This medicine is not recommended for use in patients with a known allergy to ENDOXAN 50mg Tablet 50s , other alkylating agents, or any other inactive ingredients present along with the formulation.
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Urinary outflow obstruction
This medicine is not recommended for use in patients with urinary flow obstruction or cystitis (inflammation of the urinary bladder) due to the increased risk of worsening of the patient's condition.
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Bone marrow suppression
This medicine is not recommended in patients with severe bone marrow suppression (decrease in the production of blood cells).
Warnings
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Pregnancy
This medicine is not recommended for use in pregnant women.
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Breast-feeding
This medicine is not recommended for use in breastfeeding women.
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Secondary malignancies
This medicine may increase the risk of secondary tumors. Most frequently, the urinary tract, thyroid gland, and blood are affected. Close monitoring of signs and symptoms is necessary. Therapy should be discontinued if malignancy develops.
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Blood cell count
The use of this medicine is known to lower the count of white blood cells (neutrophils) and platelets. Close monitoring of complete blood cell counts is necessary before and during therapy with this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.
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Cardiovascular diseases
This medicine should be used with extreme caution in patients with a history of cardiovascular diseases due to the increased risk of worsening of the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases.
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Lung diseases
This medicine should be used with caution in patients with a history of lung diseases due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases.
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Infections
This medicine should be used with caution due to the increased risk of severe and potentially life-threatening infections. Report any unusual symptoms such as a fever, diarrhea, sore throat, pain or burning during urination, etc. to the doctor immediately. Close monitoring of the clinical condition, appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary in some cases.
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Kidney impairment
This medicine should be used with caution in patients suffering from kidney impairment due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
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Liver impairment
This medicine should be used with caution in patients suffering from liver impairment due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
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Driving or operating machinery
This medicine may cause dizziness, drowsiness, weakness, or tiredness in some patients. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you experience any of these symptoms.
Dosage
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Missed Dose
It is advised not to miss any dose. If you miss a dose, contact your doctor immediately.
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Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Clozapine severe
- Diltiazem moderate
- Warfarin moderate
- Live attenuated vaccines and related products severe
General Instructions
Take this medicine exactly as prescribed. Do not take in larger amounts than advised/prescribed. It should be given in multiple cycles along with other chemotherapy agents. It is important to receive every scheduled dose. The blood cells count and kidney function should be assessed before starting the treatment. Any signs and symptoms of heart and lung dysfunction should be reported to the doctor on priority. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- May cause sleepiness
References
- medlineplus.gov - Cyclophosphamide [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a682080.html [cited 22/8/2020]. 2020
One of the following licensed pharmacy from the nearest location will deliver ENDOXAN 50mg Tablet 50s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
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3 reviews for ENDOXAN 50mg Tablet 50s
azharabbas –
azharabbas submitted 5 stars.
Anonymous –
submitted 5 stars.
Anonymous –
It’s my first order. I hope it will be an excellent service.