Esmeron Injection 50 mg 12 Ampx5 mL

 4,111.76

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 50 mg
Drug Form : Injection
Pack Size : 12 Ampx5 mL
Does this requires a prescription ?Yes

Esmeron Injection contains Rocuronium | belongs to Non-depolarising muscle relaxant

SKU: pg_7831_10899 Categories: ,

Alternate brands

  • Trocuronium Injection 10 mg 12 Vialx5 mL
     2,800.00
  • You can save 1311.76
  • Esmeron Injection 50 mg 10 Ampx5 mL
     3,426.28
  • You can save 685.48

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    How it works

    Esmeron Injection 50 mg 12 Ampx5 mL relaxes the skeletal muscles and helps during procedures such as an endotracheal intubation and mechanical ventilation.

    Side effects

    Major & minor side effects for Esmeron Injection 50 mg 12 Ampx5 mL

    • Muscle weakness severe
    • Difficulty in breathing severe
    • Irregular heartbeat severe
    • Swelling at the injection site rare
    • Chest tightness severe
    • Hiccups
    • Pruritus
    • Nausea

    Uses of Esmeron Injection 50 mg 12 Ampx5 mL

    What is it prescribed for?

    • Anesthesia

      This medicine is used along with general anesthesia to reduce the pain during endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

    Concerns

    Frequently asked questions

    • Onset of action

      The effect of this medicine can be observed within 1 to 2 minutes of administration of the dose.

    • Duration of Effect

      The effect of this medicine lasts for an average duration of 30 minutes in case of a 0.6 mg/kg dose and 67 minutes in case of a 1.2 mg/kg dose.

    • Safe with Alchohol?

      Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

    • Is it habit forming?

      No habit-forming tendency has been reported.

    • Usage in pregnancy?

      This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

    • Usage while breast-feeding?

      This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

    When not to use?

    • Allergy

      This medicine is not recommended for use in patients with a known allergy to Esmeron Injection 50 mg 12 Ampx5 mL or other neuromuscular blocking agents.

    Warnings

    Warnings for special population
    • Pregnancy

      This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

    • Breast-feeding

      This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

    General Warnings
    • Burns

      Patients with burns may require a higher dose of this medicine for an optimal effect.

    • Electrolyte imbalance

      This medicine should be used with caution in patients with electrolyte imbalance due to the increased risk of worsening of the patient's condition. Close monitoring of electrolytes levels is recommended during treatment with this medicine.

    • Histamine release

      This medicine should be used with caution in patients with allergies and asthma due to the increased risk of worsening of the patient's condition.

    • Malignant hyperthermia

      This medicine should be used with extreme caution in patients with malignant hyperthermia due to the increased risk of worsening of the patient's condition.

    • Paresis

      Patients with paresis may require a higher dose of this medicine for an optimal effect.

    • QT interval prolongation

      The combined use of this medicine with other general anesthetic agents may prolong QT interval in pediatric patients. Appropriate dose adjustments and close monitoring of heart and lung function are recommended during treatment with this medicine.

    • Resistance

      Patients with burns, muscle trauma, severe acid-base and/or electrolyte abnormalities may develop resistance to this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

    Dosage

    • Missed Dose

      Since this medicine is administered before surgery by a qualified healthcare professional, the likelihood of missing a dose is very low.

    • Overdose

      Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

    Interactions

    Interaction with Medicines
    • Amlodipine moderate
    • Gentamicin severe
    • Phenytoin moderate
    • Quinidine moderate
    • Procainamide moderate
    • Amikacin severe
    • Furosemide moderate
    Disease interactions
    • severe

      This medicine should be used with caution in patients with a severe liver disease due to the increased risk of serious side effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

    • severe

      This medicine should be used with caution in patients with myasthenia gravis due to the increased risk of respiratory paralysis. Close monitoring of such patients for any worsening of the condition is recommended. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

    • severe

      This medicine should be used with caution in patients with a history of pulmonary impairment due to the increased risk of respiratory depression and paralysis. Close monitoring of lung function is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

    • severe

      This medicine should be used with caution in patients with a history of cachexia due to the increased risk of severe side effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

    • moderate

      This medicine should be used with caution in patients with a history of seizures due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

    General Instructions

    This medicine should be administered by a qualified healthcare professional. Inform the doctor if you have a known allergy to this medicine. Report to the doctor all your current medicines including herbs and supplements as well as all your medical conditions before receiving this medicine.

    Other details

    • Usage does not depend on food timings
    • To be taken as instructed by doctor
    • Causes sleepiness

    References

    Additional Information>

    How to use Esmeron Injection 50 mg 12 Ampx5 mL

    Administer IV only, may be given undiluted as a bolus injection or via a continuous infusion using an infusion pump.
    Compatibility: Stable in 0.9% NaCl and D5W, this mixture should be used in 24 hours of preparation.
    Stability: Store under refrigeration (2°C-8°C) Do not freeze, when stored at room temperature it is stable for 30 days.

    what are the adverse effects of Esmeron Injection 50 mg 12 Ampx5 mL?

    High dosage produce mild vagolytic activity. Rash; injection site reactions.

    What happens if I miss a dose of Esmeron Injection 50 mg 12 Ampx5 mL?

    Adults: Intubation: By IV injection, initially 600 mcg/kg, maintenance by IV inj, 150 mcg/kg (Elderly: 75-100 mcg/kg) or maintenance by IV infusion, 300-600 mcg/kg/hr (Elderly: up to 400 mcg/kg/hr) adjusted according to response.
    Intensive care: By IV inj, initially 600 mcg/kg (optional), maintenance by IV infusion, 300-400 mcg/kg/hr for first hr, then adjusted according to response.
    Children: Not licensed for use in children for assisted ventilation in intensive care. To avoid excessive dosage in obese children, dose should be calculated on the basis of ideal weight
    Neuromuscular blockade (intermediate duration) during surgery: Neonate, initially by IV injection 600 mcg/kg, then either by IV injection, 150 mcg/kg repeated as required or by IV infusion, 300-600 mcg/kg/hr adjusted according to response; 1 mth-18 yr, initially by IV injection 600 mcg/kg, then either by IV injection, 150 mcg/kg repeated as required or by IV infusion, 300-600 mcg/kg/hr adjusted according to response.
    Assisted ventilation in intensive care: 1 mth-18 yr, initially by IV injection 600 mcg/kg (optional), then by IV infusion, 300-600 mcg/kg/hr for first hr, then adjusted according to response.

    One of the following licensed pharmacy from the nearest location will deliver Esmeron Injection 50 mg 12 Ampx5 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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