MBBS
Farmorubicin Injection RD 10 mg 1 Vialx5 mL
- Does this requires a prescription ? Yes
- Generic Name: Epirubicin
- Manufactured by : Pfizer
- Drug Strength : 10 mg
- Drug Form : Injection RD
- Pack Size : 1 Vialx5 mL
- Product SKU : pg_8368_11754
Farmorubicin Injection RD contains Epirubicin | belongs to Cytotoxic anthracycline antibiotic
Alternate brands of Farmorubicin Injection RD 10 mg 1 Vialx5 mL
Brand Name | Price | Savings |
---|---|---|
Farmorubicin Injection CS 50 mg 1 Ampx25 mL | ₨ 3,764.10 | You will pay -2947.8 more |
Farmorubicin Injection CS 10 mg 1 Ampx5 mL | ₨ 816.30 | You can save 0 |
Farmorubicin Injection RD 50 mg 1 Vialx25 mL | ₨ 3,764.10 | You will pay -2947.8 more |
E-Rubicin Injection 10 mg 1 Vialx5 mL | ₨ 670.00 | You can save 146.3 |
E-Rubicin Injection 50 mg 1 Vialx25 mL | ₨ 3,450.00 | You will pay -2633.7 more |
How it works
Farmorubicin Injection RD 10 mg 1 Vialx5 mL works by slowing or stopping the growth of cancer cells in your body.
Side effects
Major & minor side effects for Farmorubicin Injection RD 10 mg 1 Vialx5 mL
- Low WBC count severe
- Fever with chills severe
- Blood in urine and stools severe
- Red spots on skin severe
- Irregular heartbeat severe
- Joint pain severe
- Diarrhea
- Hair loss or thinning of the hair
- Irregular menstrual periods
- Change in skin color
- Decreased appetite
Uses of Farmorubicin Injection RD 10 mg 1 Vialx5 mL
What is it prescribed for?
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Adjuvant for Breast Cancer
Farmorubicin Injection RD 10 mg 1 Vialx5 mL is used along with other medications in the treatment of breast cancer.
Concerns
Frequently asked questions
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Onset of action
The peak effect of this medicine can be observed immediately after intravenous injection.
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Duration of Effect
The effect of this medicine lasts for an average duration of 3 to 4 days.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for pregnant women.
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Usage while breast-feeding?
This medicine is not recommended in breastfeeding women.
When not to use?
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Allergy
Not recommended in patients with known allergy to Farmorubicin Injection RD 10 mg 1 Vialx5 mL .
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Heart diseases
Not recommended in patients with heart failure, recent myocardial infarction or severe arrhythmias
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Previously treated with Farmorubicin Injection RD 10 mg 1 Vialx5 mL
Not recommended in patients previously treated with maximum cumulative doses of Farmorubicin Injection RD 10 mg 1 Vialx5 mL or any anthracyclines.
Warnings
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Pregnancy
This medicine is not recommended for pregnant women.
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Breast-feeding
This medicine is not recommended in breastfeeding women.
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Decrease blood cell count
This medicine may lower the white blood cells, neutrophils, and platelets. Close monitoring of blood cell count is necessary before and during each cycle. Do not start the treatment if the cell count is low.
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Infections
The chances of occurring infections are more in patients receiving this medicine. Hold the chemotherapy and start with the broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.
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Effect oh heart
This medicine is known to show toxic effects on the heart. It can cause congestive heart failure (CHF) which is a serious condition characterized by breathing difficulty, abnormal heart rhythm. The treatment should be discontinued if the symptoms appear.
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Impaired liver function
This medicine is known to cause severe liver injury by increasing the level of liver enzymes. This effect may reduce the clearance and increases its toxicity. The liver function parameters should be assessed before starting the treatment. The treatment should be discontinued if the symptoms worsen.
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Impaired kidney function
This medicine should be used with caution in patients with the kidney injury. The kidney function tests should be performed before and during the treatment. The dose of the medicine should be adjusted based on the serum creatinine levels.
Dosage
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Missed Dose
It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.
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Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Clozapine severe
- Ketoconazole moderate
- Atorvastatin moderate
- Live vaccines severe
General Instructions
This medicine is given in multiple cycles. It is important to receive the every scheduled dose and make a note of next scheduled dose. Close monitoring of blood cells counts and liver function is necessary.
Other details
- Usage does not depend on food timings
- To be taken as instructed by doctor
- Does not cause sleepiness
References
- medlineplus.gov - Epirubicin [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a603003.html [cited 14/7/2020]. 2020
How to use Farmorubicin Injection RD 10 mg 1 Vialx5 mL
Epirubicin should be administered into the tubing of a freely flowing IV infusion (0.9% NaCl or 5% glucose solution). The infusion time ranges between 3-20 min, depending on dosage and volume of the infusion solution. Avoid direct push injection. Flush well with a heparin-free solution before and after epirubicin administration.
Compatibility: Stable in D5W, LR, NS; Incompatible with any solution of alkaline pH incompatible with heparin, fluorouracil.
Stability: Store vials of injection solution in a refrigerator at 2°C-8°C (36°F-46°F). Do not freeze. Store vials of powder for solution at 25°C (77°F); excursions are permitted to 15°C-30°C (59°F-86°F). Protect from light. Discard unused portion. Store upright. Reconstituted solutions are stable for 24 hours when stored at 2°C-8°C (36°F-46°F) and protected from light, or 25°C (77°F) in normal lighting conditions. Epirubicin solution is preservative-free and should be used within 24 hours of the first penetration of the rubber stopper.
what are the adverse effects of Farmorubicin Injection RD 10 mg 1 Vialx5 mL?
Myelosuppression, cardiotoxicity, alopecia (reversible), mucositis, GI disturbances, hyperpyrexia, fever, chills, urticaria, secondary acute myelogenous leukaemia.
What happens if I miss a dose of Farmorubicin Injection RD 10 mg 1 Vialx5 mL?
Adults: IV: 100-120 mg/m² once weekly every 3-4 wk or 50-60 mg/m² days 1 and 8 every 3-4 wk
Breast cancer: CEF-120: 60 mg/m² on days 1 and 8 for 8 cycles. FEC-100: 100 mg/m² on day 1 every 21 days 6 cycles.
One of the following licensed pharmacy from the nearest location will deliver Farmorubicin Injection RD 10 mg 1 Vialx5 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
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