₨ 9,280.00
MBBS
Fludakebir Injection 50 mg 1 Vial
- Does this requires a prescription ? Yes
- Generic Name: Fludarabine Phosphate
- Manufactured by : ONCOGENE Pharmaceuticals
- Drug Strength : 50 mg
- Drug Form : Injection
- Pack Size : 1 vial
- Product SKU : pg_9077_12735
Fludakebir Injection contains Fludarabine Phosphate | belongs to Antimetabolite
Alternate brands of Fludakebir Injection 50 mg 1 Vial
Brand Name | Price | Savings |
---|---|---|
Fludara IV Injection 50 mg 5 Vial | ₨ 66,313.50 | You will pay -57033.5 more |
How it works
Fludakebir Injection 50 mg 1 Vial prevents the growth and spread of cancer cells in the body.
Side effects
Major & minor side effects for Fludakebir Injection 50 mg 1 Vial
- Nausea and Vomiting
- Blood in urine and stools
- Chest pain
- Black or tarry stools
- Constipation
- Shortness of breath
- Stomach pain
- Blurred vision
- Headache
- Weight gain
Uses of Fludakebir Injection 50 mg 1 Vial
What is it prescribed for?
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Chronic Lymphocytic Leukemia
This medicine is used for the treatment of chronic lymphocytic leukemia which is a cancer of the blood and the bone marrow.
Concerns
Frequently asked questions
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Onset of action
The amount of time required for this medicine to show its action is not clinically established.
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Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit-forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.
When not to use?
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Allergy
This medicine is not recommended for use if you have a known allergy to Fludakebir Injection 50 mg 1 Vial or any other inactive ingredient present along with it.
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Severe renal impairment
The intravenous form of this medicine is not recommended for use in patients with severe kidney impairment (CrCl<30 ml/min) due to the risk of worsening of the patient's condition.
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Decompensated hemolytic anemia
This medicine is not recommended for use in patients with decompensated hemolytic anemia (a red blood cell disorder) due to the risk of worsening of the patient's condition.
Warnings
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Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine.
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Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.
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Use in children
This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.
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Risk of infections
Use of this medicine may weaken the immune system and may make you more vulnerable to infections. It is advised that you avoid coming in contact with people suffering from an infection while receiving this medicine.
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Driving or operating machinery
Use of this medicine may cause dizziness, tiredness, blurred vision, etc. in some patients. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you experience any of these symptoms during treatment with this medicine.
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Liver impairment
This medicine should be used with extreme caution in patients suffering from liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
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Kidney impairment
This medicine should be used with extreme caution in patients suffering from kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient. The intravenous form of this medicine is not recommended for use in patients with severe kidney impairment (CrCl<30 ml/min).
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Bonemarrow suppression
This medicine should be used with caution in patients having conditions like thrombocytopenia, agranulocytosis, anemia, or bone marrow suppression due to the increased risk of worsening of the patient's condition. A complete blood count should be performed before initiating treatment with this medicine. Close monitoring of blood counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Dosage
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Missed Dose
Injection: Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. If you miss any scheduled session, contact your doctor immediately for further instructions. Tablet: Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
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Overdose
Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected. Tablet: Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Live attenuated vaccines and related products severe
- Etanercept severe
- Azathioprine moderate
- Clozapine moderate
- Pentostatin severe
General Instructions
Injection: This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine. Tablet: Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- May cause sleepiness
References
- drugbank - Fludarabine [Internet]. Available from: https://go.drugbank.com/drugs/DB01073 [cited 1/12/20211]. 2021
How to use Fludakebir Injection 50 mg 1 Vial
IV: Administer IV over 15-30 min or continuous infusion. Reconstitute vials with SWFI, NS, or D5W to a concentration of 10-25 mg/mL. Standard IV dilution: 50-100 mL D5W or NS.
Compatibility: Stable in D5W, NS, SWFI.
Stability: Store intact vials under refrigeration at 2°C-8°C. Reconstituted vials are stable for 16 days at room temperature of 15°C-30°C.
what are the adverse effects of Fludakebir Injection 50 mg 1 Vial?
Myelosuppression (which may be cumulative) and immunosuppression (with an increased risk of opportunistic infection). Idiosyncratic CNS and pulmonary toxicity have been rarely reported.
What happens if I miss a dose of Fludakebir Injection 50 mg 1 Vial?
Adults: 50 mg IV daily for 5 days every 28 days. See literature. Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Fludakebir Injection 50 mg 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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