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Glandin E-2 Vag Gel 2 mg 3 gm

Glandin E-2 Vag Gel contains Dinoprostone | belongs to Prostaglandin

Alternate brands of Glandin E-2 Vag Gel 2 mg 3 gm

Brand Name Price Savings
Vprestone-2 Vag tablet 3 mg 1’s  443.00 You can save 82
Vprestone-2 Vag tablet 3 mg 4’s  1,773.00 You will pay -1248 more
Prostin E-2 Vag tablet 3 mg 4’s  4,066.43 You will pay -3541.43 more
Preglan E2 Vag tablet 3 mg 1’s  382.50 You can save 142.5
Glandin E-2 Vag tablet 3 mg 1’s  599.00 You will pay -74 more
List of alternate brands

How it works

Glandin E-2 Vag Gel 2 mg 3 gm is a natural substance (prostaglandin) that your body makes in preparation for labor. It softens and widens the opening of the womb and increases contractions.

Side effects

Major & minor side effects for Glandin E-2 Vag Gel 2 mg 3 gm

  • Nausea and vomiting
  • Diarrhea
  • Abdominal cramps
  • Fever
  • Constipation
  • Swelling of genital area
  • Shortness of breath

Uses of Glandin E-2 Vag Gel 2 mg 3 gm

What is it prescribed for?

  • Induction of labor

    This medicine is used for relaxing and softening the cervix and induce uterine contractions for the induction of labor.

  • Termination of pregnancy

    This medicine is used for the termination of pregnancy by inducing uterine contractions and expelling the fetus out.

Concerns

Frequently asked questions

  • Onset of action

    The effect of this medicine can be observed within 10 minutes after vaginal insertion in first and second trimester pregnancies.

  • Duration of Effect

    The effects of this medicine last up to 2-3 hours after vaginal insertion.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit-forming tendencies were reported.

  • Usage in pregnancy?

    Use of this medicine is not recommended for pregnant women other than for the indicated uses such as the induction of labor and termination of pregnancy. Otherwise, the risk of birth defects, abortion, and other abnormalities are very high.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

When not to use?

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to Glandin E-2 Vag Gel 2 mg 3 gm or any other inactive ingredients present in the formulation.

  • Cesarean section

    This medicine is not recommended for patients who have a history of cesarean section due to the increased risk of adverse effects.

  • Grand multiparae

    This medicine is not recommended for use in patients with a history of 6 or more term pregnancies due to the increased risk of worsening of the patient's condition.

  • Acute Pelvic Inflammatory Disease

    This suppository form of this medicine is not recommended for use in patients with acute pelvic inflammatory disease due to the increased risk of worsening of the patient's condition.

Warnings

Warnings for special population
  • Pregnancy

    Use of this medicine is not recommended for pregnant women other than for the indicated uses such as the induction of labor and termination of pregnancy. Otherwise, the risk of birth defects, abortion, and other abnormalities are very high.

  • Breast-feeding

    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

General Warnings
  • Use with Caution

    This medicine should be used with caution in patients with epilepsy, glaucoma, hepatic/renal impairment, pulmonary disease.

  • Uterine rupture

    This medicine has been associated with cases of uterine rupture when used for labor induction in some cases. Caution is advised while using this medicine if the patient is in the late thirties and beyond or the delivery is cesarean.

  • For hospital use only

    This medicine should be administered only by trained obstetrical personnel in a hospital setting with appropriate obstetrical care facilities.

Dosage

  • Missed Dose

    Since this medicine is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dose is very low.

  • Overdose

    Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions

Interaction with Medicines
  • Misoprostol severe
  • Mifepristone severe
  • Oxytocin severe
  • Ergonovine severe
Disease interactions
  • moderate

    This medicine should be used with caution in patients with asthma due to the increased risk of bronchospasm, decreased pulmonary blood flow, and/or increased pulmonary arterial pressure. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

  • moderate

    This medicine should be used with caution in patients with decreased blood pressure due to the increased risk of adverse effects. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

General Instructions

This medicine should be administered only by trained obstetrical personnel in a hospital setting with appropriate obstetrical care facilities. Detect whether the patient is allergic to this medicine or any other prostaglandin analogs before initiating the treatment.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • Does not cause sleepiness

References

Additional Information:

How to use Glandin E-2 Vag Gel 2 mg 3 gm

Continuous IV infusion: Administered either centrally or peripherally. Do not administer bolus and take care not to quickly flush lines that may contain dinoprostone.
Reconstitution: Dilute 500 mcg (0.5 mL) of the 1 mg in 1 mL injection solution to 5 mL with 0.9% NaCl to give 100 mcg in 1 mL. Use this 100 mcg in 1 mL solution to make up a 50 mL syringe for infusion.

what are the adverse effects of Glandin E-2 Vag Gel 2 mg 3 gm?

Uterine hypercontractility, hypertonus; altered fetal heart rate; postpartum haemorrhage; post-op infection; vaginal irritation; amniotic fluid embolism; GIT disturbances.

What happens if I miss a dose of Glandin E-2 Vag Gel 2 mg 3 gm?

Vaginal Gel: Adults: By vagina, induction of labour, inserted high into posterior fornix (avoid administration into cervical canal), 1 mg (unfavourable primigravida 2 mg), followed after 6 hr by 1-2 mg if required; max gel 3 mg (unfavourable primigravida 4 mg).
Vaginal Pessary/Tab: Adults: By vagina, induction of labour, inserted high into posterior fornix; 3 mg, followed after 6-8 hr by 3 mg if labour is not established; max 6 mg (vaginal tab/pessary).
Inj 1 mg: Induction of labour: Adults: By IV: See literature.
Inj 10 mg: Termination of pregnancy: Adults: By IV: See literature.
Children: Not applicable.

One of the following licensed pharmacy from the nearest location will deliver Glandin E-2 Vag Gel 2 mg 3 gm. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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