₨ 633.00
MBBS
Gratron Injection 3 mg 1 Amp
- Does this requires a prescription ? Yes
- Generic Name: Granisetron
- Manufactured by : Graton
- Drug Strength : 3 mg
- Drug Form : Injection
- Pack Size : 1 AMP
- Product SKU : pg_10300_14375
Gratron Injection contains Granisetron | belongs to 5HT3-antagonist
Alternate brands of Gratron Injection 3 mg 1 Amp
| Brand Name | Price | Savings |
|---|---|---|
| Kytril tablet 1 mg 10’s | ₨ 3,795.79 | You will pay -3162.79 more |
| Kytril Injection 3 mg 5 Amp | ₨ 4,525.66 | You will pay -3892.66 more |
| Graniset Injection 3 mg 5 Amp | ₨ 3,165.00 | You will pay -2532 more |
| Graniset tablet 1 mg 10’s | ₨ 2,650.00 | You will pay -2017 more |
| Granicip Injection 3 mg 1 Amp | ₨ 633.00 | You can save 0 |
How it works
Gratron Injection 3 mg 1 Amp works by blocking serotonin, a natural substance in the body that causes nausea and vomiting.
Side effects
Major & minor side effects for Gratron Injection 3 mg 1 Amp
- Headache
- Constipation
- Diarrhea
- Rashes
- Dizziness
- Sleepiness
- Irregular heartbeat
Uses of Gratron Injection 3 mg 1 Amp
What is it prescribed for?
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Chemotherapy or Radiation therapy induced nausea and vomiting
This medicine is used to prevent nausea and vomiting associated with chemotherapy or radiation therapy.
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Post operative nausea and vomiting
This medicine may also be used to prevent nausea and vomiting associated with surgeries.
Concerns
Frequently asked questions
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Onset of action
The effect of this medicine can be observed within 30 to 60 minutes of the administration of the dose.
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Duration of Effect
The effect of this medicine lasts for a maximum duration of 24 hours.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit forming tendency has been reported.
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding for a specific period of time or may prescribe an alternative medicine based on your clinical condition.
When not to use?
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Allergy
This medicine is not recommended for use in patients with a known allergy to Gratron Injection 3 mg 1 Amp or any other inactive ingredients present in the formulation.
Warnings
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Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
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Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding for a specific period of time or may prescribe an alternative medicine based on your clinical condition.
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Serotonin Syndrome
This medicine should be used with caution due to the increased risk of serotonin syndrome. This risk is especially higher in patients receiving serotogenic drugs. Report any symptoms such as dizziness, increased heart rate, changes in blood pressure, flushing, vomiting, nausea, diarrhea, etc. to the doctor immediately. Appropriate corrective measures or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
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Other medicines
This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.
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Liver disease
This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
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QT Prolongation
This medicine should be used with extreme caution in patients with prolonged QT due to the increased risk of worsening of the patient's condition. Regular monitoring of electrolyte levels and kidney function tests are necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Dosage
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Missed Dose
Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
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Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Tramadol severe
- Apomorphine severe
- Formoterol moderate
- Fentanyl severe
- Azithromycin moderate
- Selective Serotonin Reuptake inhibitors severe
- Hydroxychloroquine severe
- Promazine moderate
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This medicine should be used with caution in patients with pre-existing arrhythmias or cardiac conduction disorders due to the increased risk of worsening of the patient's condition. Close monitoring of heart function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
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This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
General Instructions
Take this medicine exactly as directed by the doctor. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine before completion of the course/without consulting your doctor.
Other details
- Usage does not depend on food timings
- To be taken as instructed by doctor
- May cause sleepiness
References
- medlineplus.gov - Granisetron [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a601211.html [cited 23/7/2020]. 2020
How to use Gratron Injection 3 mg 1 Amp
IV: Administer as rapid (30 second) IV push or a short (5-10 min) infusion. For prevention of PONV, administer before induction of anaesthesia or before reversal of anaesthesia. For PONV, administer undiluted over 30 seconds.
Compatibility: Stable in D5 ½ NS, D5NS, D5W, NS, bacteriostatic water. Incompatible with amphotericin (Y-site administration).
Stability: Store at 25°C-30°C. Do not freeze vials. Protect from light. Stable when mixed in NS or D5W for 7 days under refrigeration and for 3 days at room temperature.
what are the adverse effects of Gratron Injection 3 mg 1 Amp?
Headache, insomnia, GI upset, constipation, asthaenia, pain.Transient rise in liver enzymes. Reports of serotonin syndrome. Sancuso: also reports of application site reactions ( discontinue if severe).
What happens if I miss a dose of Gratron Injection 3 mg 1 Amp?
ORAL: Adults: 1 mg twice daily or 2 mg once daily, initial dose administered one hr prior to cytostatic therapy. Children: Not recommended.
INFUSION: Cytostatic induced nausea and vomiting: Adults: Usually 3 mg diluted in 20-50 mL infusion fluid administered by IV infusion over 5 min or diluted in 15 mL infusion fluid administered by IV bolus Inj over 30 sec. If necessary repeat at intervals of at least 10 min; max 9 mg in 24 hr. Children: 40 mcg/kg (upto 3 mg) diluted in 10-30 mL infusion fluid administered by IV infusion over 5 min. If necessary repeat once within 24 hr at least 10 min after initial infusion.
Post-operative nausea and vomiting: Adults: 1 mg diluted to 5 mL administered by slow IV injection over 30 sec prior to induction of anaesthesia.
PATCH: Nausea and vomiting induced by cytotoxic chemotherapy: Adults: For planned duration of 3-5 days where oral anti-emetics cannot be used, transdermally, apply one 3.1 mg/24 hr patch to clean, dry, non-irritated, non-hairy skin on upper arm (or abdomen if upper arm cannot be used) 24-48 hr before treatment, remove at least 24 hr after completing chemotherapy (patch may be worn for up to 7 days). Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Gratron Injection 3 mg 1 Amp. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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