₨ 138.00
MBBS
GT Zole capsule 150 mg 1’s
- Does this requires a prescription ? Yes
- Generic Name: Fluconazole
- Manufactured by : GT Pharma
- Drug Strength : 150 mg
- Drug Form : Capsule
- Pack Size : 1s
- Product SKU : pg_9640_13420
GT Zole capsule contains Fluconazole | belongs to Triazole antifungal
Alternate brands of GT Zole capsule 150 mg 1’s
| Brand Name | Price | Savings |
|---|---|---|
| Zolanix capsule 150 mg 4’s | ₨ 497.88 | You will pay -359.88 more |
| Zolanix capsule 150 mg 1’s | ₨ 150.00 | You will pay -12 more |
| Zenok capsule 150 mg 1’s | ₨ 138.00 | You can save 0 |
| Zefung capsule 150 mg 1’s | ₨ 150.00 | You will pay -12 more |
| Zanoc suspension 50 mg 35 mL | ₨ 210.00 | You will pay -72 more |
How it works
GT Zole capsule 150 mg 1’s acts by stopping the production of a certain vital component for the fungi. This results in disruption of cell membrane formation process and growth of the organism are stunted.
Side effects
Major & minor side effects for GT Zole capsule 150 mg 1’s
- Headache severe
- Nausea and Vomiting severe
- Abdominal pain
- Diarrhea
- Skin rash
- QT Prolongation severe
- Alopecia
- Seizures severe
- Swelling of face, lips, eyelids, tongue, hands and feet
Uses of GT Zole capsule 150 mg 1’s
What is it prescribed for?
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Oropharyngeal Candidiasis
GT Zole capsule 150 mg 1’s is used to treat fungal infection in the mouth.
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Esophageal Candidiasis
GT Zole capsule 150 mg 1’s is used to treat the fungal infection of the oesophagus or the "food pipe" causing odynophagia or painful swallowing.
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Cryptococcal Meningitis
GT Zole capsule 150 mg 1’s is used to treat meningitis, a rare infection that affects the delicate membranes called meninges that covers the brain and spinal cord, caused by a group of fungi of Cryptococcus strain.
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Vaginal Candidiasis
GT Zole capsule 150 mg 1’s is used to treat yeast infection in the female genital organ causing pain, itching and burning sensation with unusual discharge.
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Urinary Tract Infection
GT Zole capsule 150 mg 1’s is used to treat fungal infections of the urinary tract.
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Peritonitis
GT Zole capsule 150 mg 1’s is used to treat the fungal infection that causes inflammation of the peritoneum, a thin layer of tissue that covers the inside of the abdomen and most of the organs present within the abdomen.
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Candidemia
GT Zole capsule 150 mg 1’s is used to treat Candidemia, a condition in which the fungus Candida enters the bloodstream and from the blood to eyes, kidneys, liver and brain causing Invasive candidemia.
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Prophylaxis of Infections in Special Population
Prophylaxis of Infections in Special Population
When not to use?
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Allergy
GT Zole capsule 150 mg 1’s is not recommended for use if you have a known allergy to this medicine.
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QT Interval prolonging drugs
GT Zole capsule 150 mg 1’s is not recommended for co-administration with drugs that are known to cause specific changes in heart rhythm.
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Liver Injury
GT Zole capsule 150 mg 1’s can cause moderate to severe side effects on liver and may result in liver failure in rare cases. Any known incidence of liver disease should be reported to the doctor. Dosage adjustments and safety monitoring might be required in such cases.
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Allergy
GT Zole capsule 150 mg 1’s and other medicines of the same group i.e Azoles could cause allergy in some patients. Any such known instance of allergy should be reported to the doctor.
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Skin disorders
GT Zole capsule 150 mg 1’s may cause a condition where the skin starts to peel off in some patients. If you have had fungal infections in the past, then symptoms of infections should be monitored closely.
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Heart condition
Caution is advised while using this medicine in patients with a history of cardiovascular disorder. Suitable dose adjustment and safety monitoring might be required in such cases.
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Kidney disease
It is recommended to report any history of or active renal disorders to the doctor prior to the start of therapy with this medicine as necessary dosage adjustments may be made by the doctor for the safe use of this medicine.
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Dizziness and seizures
This medicine may cause dizziness or even seizures in few patients. Hence caution is adviced while driving and operating heavy machinery after taking this medicine.
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Other drugs and supplements
GT Zole capsule 150 mg 1’s is known to interact with a large number of other medicines and hence it becomes mandatory for you to report the use of all of them to the doctor.
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Birth control
GT Zole capsule 150 mg 1’s may interact with the birth control pill you might be consuming and hence contraception might be ineffective. Alternate means of birth control are to be adopted while you are taking this medicine.
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Geriatric use
GT Zole capsule 150 mg 1’s must be used with caution in elderly since the effects are more severe, warranting an adjustment in dosage.
Dosage
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Missed Dose
Oral and topical forms: The missed dose of GT Zole capsule 150 mg 1’s should be taken/used as soon as possible. It is advisable to skip the missed dose if it is already the time for your next scheduled dose. Do not double the dose to make up for the missed one. Since GT Zole capsule 150 mg 1’s injection is mostly administered by a healthcare professional in a clinical setting, the likelihood of missing a dose is very low.
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Overdose
Oral and Topical forms: Seek emergency medical attention or contact your doctor in case of an overdose with GT Zole capsule 150 mg 1’s . Injection: Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
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severe
GT Zole capsule 150 mg 1’s should be carefully administered in patients with impaired hepatic function. Suitable dosage adjustments and safety monitoring are necessary in such cases.
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moderate
GT Zole capsule 150 mg 1’s should be very carefully administered in patients with pre-existing heart conditions. Suitable dosage adjustments and safety monitoring are recommended in such cases.
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moderate
GT Zole capsule 150 mg 1’s should be carefully administered in patients with impaired kidney function. Suitable dosage adjustments and safety monitoring are necessary in such cases.
General Instructions
GT Zole capsule 150 mg 1’s should be taken following all the instructions that are given by your doctor. To ensure complete recovery and no relapse, the full course of treatment should be followed. It is more effective if taken at the same time on all days. Any instance of side effect should be reported to the doctor immediately.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- May cause sleepiness
References
- practo.com - Fluconazole [Internet]. Available from: https://www.practo.com/medicine-info/fluconazole-117-api [cited 07 september 2019]. 8 Feb 2018
- pubchem.ncbi.nlm.nih.gov - Fluconazole [Internet]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/3365#section=Top [cited 07 september 2019]. 2008 Apr;29
- dailymed.nlm.nih.gov - FLUCONAZOLE [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6ebf24fd-41cd-4b3c-8176-a1436253ba2d [cited 07 september 2019]. March 2, 2019
- drugbank.ca - Fluconazole [Internet]. Available from: https://www.drugbank.ca/drugs/DB00196 [cited 07 september 2019]. 2008 Apr;29
- toxnet.nlm.nih.gov - TOXNET [Internet]. Available from: https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~sgFUQe:1 [cited 07 september 2019]. notavailable
How to use GT Zole capsule 150 mg 1’s
IV: Fluconazole be administered by IV Infusion over approx 1-2 hours; do not exceed 200 mg/hour when giving IV Infusion. Standard diluent: 200 mg/100 mL NS (premixed); 400 mg/200 mL NS (premixed).
Compatibility: Stable in D5W, LR, NS.
Y-site administration:
Drug to Drug IV Compatibility: Acyclovir, amikacin, amiodarone, aztreonam, bumetanide, cephazolin, cefepime, cimetidine, ciprofloxacin, cisatracurium, dexamethasone, diltiazem, diphenhydramine, dobutamine, dopamine, enalapril, epinephrine, esmolol, famotidine, fentanyl, gentamicin, heparin, hydrocortisone, hydromorphone, insulin regular, labetalol, lansoprazole, levofloxacin, linezolid, lorazepam, magnesium sulphate, meropenem, methylprednisolone, metoclopramide, metronidazole, midazolam, morphine, nitroglycerin, nitroprusside, norepinephrine, ondansetron, phenylephrine, piperacillin/tazobactam, propofol, ranitidine, tobramycin, vancomycin, vasopressin, vecuronium.
Drug to Drug IV Incompatibility: Amphotericin B, amphotericin B cholesteryl sulphate complex, ampicillin, calcium gluconate, cefoxitin, ceftazidime, ceftriaxone, cefuroxime, chloramphenicol, clindamycin, co-trimoxazole, diazepam, digoxin, erythromycin lactobionate, furosemide, haloperidol, hydroxyzine, imipenem/cilastatin, pantoprazole, pentamidine, piperacillin, ticarcillin.
When admixed: Incompatible with co-trimoxazole.
Stability: Store vial at 5°C-30°C. Do not freeze. Do not unwrap until ready for use.
what are the adverse effects of GT Zole capsule 150 mg 1’s?
GI upset, headache, rash, altered LFTs. Reports of Stevens-Johnson syndrome and toxic epidermal necrolysis (discontinue).
What happens if I miss a dose of GT Zole capsule 150 mg 1’s?
Vaginal candidiasis and candidal balanitis: Adults: Orally, a single dose of 150 mg.
Mucosal candidiasis (except genital): Adults: Orally, 50 mg daily (100 mg daily in unusually difficult infections) given for 7-14 days in oropharyngeal candidiasis (max 14 days except in severely immunocompromised patients); for 14 days in atrophic oral candidiasis associated with dentures; for 14-30 days in other mucosal infections (e.g. oesophagitis, candiduria, non-invasive bronchopulmonary infections). Children: Orally or by IV infusion, 3-6 mg/kg on first day then 3 mg/kg daily (every 72 hr in neonates up to 2 wk old, every 48 hr in neonates of 2-4 wk old).
Tinea pedis, corporis, cruris, versicolor and dermal candidiasis: Adults: Orally 50 mg daily for 2-4 wk (for up to 6 wk in tinea pedis); max duration of treatment 6 wk.
Invasive candidal infections (including candidaemia and disseminated candidiasis) and cryptococcal infections (including meningitis), Orally or IV Infusion, 400 mg on first day then 200-400 mg daily; max 800 mg daily in severe infections. (unlicensed dose); treatment continued according to response (at least 8 weeks for cryptococcal meningitis); Children: 6-12 mg/kg daily (every 72 hrs in neonates up to 2 weeks old, every 48 hrs in neonate 2-4 weeks old); max. 800 mg daily (unlicensed dose).
Prevention of relapse of cryptococcal meningitis in AIDS patients after completion of primary therapy: Adults: Orally 100-200 mg daily.
Prevention of fungal infections in immunocompromised patients following cytotoxic chemotherapy or radiotherapy: Adults: Orally or by IV infusion 50-400 mg daily adjusted according to risk; 400 mg daily if high risk of systemic infections e.g. following bone-marrow transplantation; commence treatment before anticipated onset of neutropenia and continue for 7 days after neutrophil count in desirable range. Children: According to extent and duration of neutropenia, 3-12 mg/kg daily (every 72 hr in neonates up to 2 wk old, every 48 hr in neonates of 2-4 wk old); max. 400 mg daily.
One of the following licensed pharmacy from the nearest location will deliver GT Zole capsule 150 mg 1’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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