₨ 25.50
MBBS
Labetalol Injection IV 50 mg 1 Vialx10 mL
- Does this requires a prescription ? Yes
- Generic Name: Labetalol
- Manufactured by : ZAFA PHARMACEUTICAL LABORATORIES (PVT) LTD.
- Drug Strength : 50 mg
- Drug Form : Injection IV
- Pack Size : 1 Vialx10 mL
- Product SKU : pg_12357_17180
Labetalol Injection IV contains Labetalol | belongs to Beta-blocker
Alternate brands of Labetalol Injection IV 50 mg 1 Vialx10 mL
| Brand Name | Price | Savings |
|---|---|---|
| Labetalol tablet 100 mg 20’s | ₨ 400.00 | You will pay -374.5 more |
How it works
Labetalol Injection IV 50 mg 1 Vialx10 mL works by reducing the blood pressure by relaxing the blood vessels and also by slowing the heart rate.
Uses of Labetalol Injection IV 50 mg 1 Vialx10 mL
What is it prescribed for?
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Hypertension
Labetalol Injection IV 50 mg 1 Vialx10 mL is used in the treatment of Hypertension which is an increase in the blood pressure caused by genetic and/or environmental factors.
Concerns
Frequently asked questions
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Onset of action
The effect of this medicine can be observed in 20 to 120 minutes after an oral dose and 2 to 3 minutes after an intravenous dose.
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Duration of Effect
The effect of this medicine can last for an average duration of 24 hours.
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Safe with Alchohol?
Consumption of alcohol with this medicine may lower the blood pressure and may cause symptoms like dizziness, headache, change in pulse or heart rate. The patient should be counseled about these effects and advised not to perform activities that require mental alertness like driving or operating machinery.
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Is it habit forming?
No habit forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for pregnant women.
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Usage while breast-feeding?
This medicine is known to excreted in breast milk. It is recommended in breastfeeding women only if necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
When not to use?
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Allergy
Not recommended in patients with known allergy to Labetalol Injection IV 50 mg 1 Vialx10 mL or other beta blockers.
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Asthma
Not recommended in the patients with known history of lung diseases like asthma, bronchospasm and chronic obstructive pulmonary disease (COPD)
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Heart block greater than first degree
Not recommended in patients with 2nd or 3rd degree AV block.
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Sinus Bradycardia
Not recommended in the patients with the condition like Sinus Bradycardia.
Warnings
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Pregnancy
This medicine is not recommended for pregnant women.
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Breast-feeding
This medicine is known to excreted in breast milk. It is recommended in breastfeeding women only if necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
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Major surgery
Labetalol Injection IV 50 mg 1 Vialx10 mL is given with caution in the patients who are scheduled for a major surgery. An anesthetic agent with little negative inotropic activity should be selected to minimize the effect on the heart.
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Lung Disease
Labetalol Injection IV 50 mg 1 Vialx10 mL should be used with caution in the patients with lung disease who do not respond to other antihypertensives. Start with the lowest possible dose and increase the dose based on the clinical condition.
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Diabetes
Labetalol Injection IV 50 mg 1 Vialx10 mL should be administered with caution in patients with diabetes. It may mask the hypoglycemic symptoms. Regular monitoring of blood glucose levels is necessary. An alternate medicine should be considered based on the clinical condition.
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Sports
It is advised to not indulge in certain sports while consuming this medicine. Archery, racing, shooting and other high-risk sports should be avoided. Sportspersons should refer to the list of banned medicines published by World Anti-Doping Agency while participating in specific sports events.
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Hyperthyroidism
Labetalol Injection IV 50 mg 1 Vialx10 mL should be administered with caution in patients with increased thyroid levels. Abrupt withdrawal of this medicine may lead to a life-threatening condition called thyroid storm. Frequent monitoring of thyroid levels is necessary. An alternate medicine should be considered based on the clinical condition.
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Pediatric use
This medication should not be administered in children.
Dosage
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Missed Dose
The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.
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Overdose
Seek emergency medical treatment or contact the doctor in case of overdose.
Interactions
Interaction with Medicines- Corticosteroids moderate
- Antidiabetic medicines moderate
- Beta-2 adrenergic bronchodilators severe
General Instructions
Take Labetalol Injection IV 50 mg 1 Vialx10 mL as advised by the doctor. Do not take in larger amounts than prescribed. Do not stop taking this medicine without consulting your doctor. Inform the doctor if you are a diabetic patient or having any lung disease.
References
- practo.com - Labetalol [Internet]. Available from: https://www.practo.com/medicine-info/labetalol-484-api [cited 2 october 2019]. 8 Jan 2018
- dailymed.nlm.nih.govHCL - LABETALOL HCL [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=56ab2ff4-14a6-4297-afd8-56b92e1f64a0 [cited 2 october 2019]. November 24, 2017
How to use Labetalol Injection IV 50 mg 1 Vialx10 mL
Administer slowly over 2 min by direct IV or by continuous IV infusion, at an initial rate of 2 mg/min with subsequent adjustments based on BP response. Standard diluent: 500 mg/250 mL D5W. Keep patient in supine position for 3 hours after IV administration.
Compatibility: Stable in D5LR, D5NS, D5W, LR, NS.
Y-site administration:
Drug to Drug IV Compatibility: Amikacin, amiodarone, aztreonam, bumetanide, calcium gluconate, cimetidine, diltiazem, diphenhydramine, dobutamine, dopamine, enalapril, epinephrine, esmolol, famotidine, fentanyl, fluconazole, gentamicin, hydromorphone, imipenem, levofloxacin, linezolid, lorazepam, magnesium sulphate, methylprednisolone, metoclopramide, metronidazole, midazolam, milrinone, nitroglycerin, nitroprusside, norepinephrine, ondansetron, phenylephrine, propofol, ranitidine, tobramycin, vancomycin, vasopressin, vecuronium.
Drug to Drug IV Incompatibility: Acyclovir, amphotericin B cholesteryl sulphate complex, cefoperazone, ceftriaxone, dexamethasone, hydrocortisone, insulin regular, lansoprazole, nafcillin, pantoprazole, piperacillin/tazobactam, thiopental, warfarin.
When admixed: Incompatible with sodium bicarbonate.
Stability: Store at room temperature. Do not freeze. Protect from light. The solution is clear to slightly yellow. For parenteral admixture, stability at room temperature is 25°C and refrigeration temperature (4°C) for 3 days.
UNLICENSED USE
Children: Hypertensive emergencies: INJECTION: IV infusion: Neonate, 500 mcg/kg/hr adjusted at intervals of at least 15 minutes according to response, max 4 mg/kg/hr; 1 mth-12 yr, initially 0.5-1 mg/kg/hr adjusted at intervals of at least 15 minutes according to response, max. 3 mg/kg/hr; 12-18 yr, 30-120 mg/hr adjusted at intervals of at least 15 minutes according to response. In hypertensive encephalopathy reduce blood pressure to normotensive level over 24-48 hr (more rapid reduction may lead to cerebral infarction, blindness and death). If child fitting, reduce blood pressure rapidly, but not to normal levels.
Hypertension: ORAL: 1 mth-12 yr, 1-2 mg/kg 3-4 times a day; 12-18 yr, initially 50-100 mg twice daily increased if required at intervals of 3-14 days to usual dose of 200-400 mg twice daily (3-4 divided doses if higher), max 2.4 gm daily. INJECTION: IV injection: 1 mth-12 yr, 250-500 mcg/kg as a single dose; max. 20 mg; 12-18 yr, 50 mg over at least 1 minute, repeated after 5 minutes if necessary; max. total dose 200 mg.
what are the adverse effects of Labetalol Injection IV 50 mg 1 Vialx10 mL?
Cardiovascular effects including bradycardia, postural hypotension. Rarely, heart failure, increased AV block, cardiac arrhythmias. Raynaud’s phenomenon cold extremities, sexual dysfunction. GI, sleep and CNS disturbances. Dyspnoea rarely, bronchospasm. Skin reactions, withdraw if unexplained dry eyes or rash. Fatigue, paraesthesia, peripheral neuropathy, arthralgia, myopathy, altered blood sugar, haematology and lipid levels.
What happens if I miss a dose of Labetalol Injection IV 50 mg 1 Vialx10 mL?
ORAL: Adults: Initially 100 mg twice daily with food increasing if necessary at 14 day intervals; max 2.4 gm daily in three or four divided doses. Elderly: Initially 50 mg twice daily. Children: Not recommended.
INJECTION: Adults: IV: 20 mg (0.25 mg/kg for 80 kg patient) by IV injection over 2 min; may be administered 40-80 mg at 10 min intervals; up to 300 mg total dose. IV Infusion: Initial 2 mg/min; titrate to response up to 300 mg total dose, if needed. Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Labetalol Injection IV 50 mg 1 Vialx10 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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1 review for Labetalol Injection IV 50 mg 1 Vialx10 mL
Abdul Qadeer –
excellent