₨ 55.67
MBBS
Lanoxin Injection 500 mcg 5 Amp
- Does this requires a prescription ? Yes
- Generic Name: Digoxin
- Manufactured by : Glaxosmithkline
- Drug Strength : 500 mcg
- Drug Form : Injection
- Pack Size : 5 AMP
- Product SKU : pg_12451_17303
Lanoxin Injection contains Digoxin | belongs to Cardiac glycoside
Alternate brands of Lanoxin Injection 500 mcg 5 Amp
| Brand Name | Price | Savings |
|---|---|---|
| Lanoxin tablet 250 mcg 100’s | ₨ 143.63 | You will pay -87.96 more |
| Lanoxin tablet 250 mcg 50’s | ₨ 74.59 | You will pay -18.92 more |
| Doxin Liqd 50 mcg/mL 120 mL | ₨ 80.50 | You will pay -24.83 more |
| Doxin Liqd 50 mcg/mL 60 mL | ₨ 40.25 | You can save 15.42 |
| Digox tablet 250 mcg 50’s | ₨ 40.00 | You can save 15.67 |
How it works
Lanoxin Injection 500 mcg 5 Amp works by affecting certain minerals (sodium and potassium) inside heart cells. This reduces strain on the heart and helps it maintain a normal, steady, and strong heartbeat.
Side effects
Major & minor side effects for Lanoxin Injection 500 mcg 5 Amp
- Dizziness severe
- Irregular heartbeat severe
- Stomach pain severe
- Vomiting severe
- Anxiety
- Confusion
- Depression
- Rash
- Diarrhea
- Blurred vision rare
- Loss of appetite rare
Uses of Lanoxin Injection 500 mcg 5 Amp
What is it prescribed for?
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Congestive Heart Failure
Lanoxin Injection 500 mcg 5 Amp is used in the treatment of congestive heart failure which is a type of heart disease, characterized by thickening of the walls of the left ventricle.
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Fibrillation
Lanoxin Injection 500 mcg 5 Amp is used in the treatment of atrial fibrillation which is a type of heart disease characterized by irregular heartbeats and leads to decreased blood flow.
Concerns
Frequently asked questions
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Onset of action
The effect of this medicine can be observed in 0.5 to 2 hours for an oral tablet and 5 to 30 minutes for an intravenous dose.
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Duration of Effect
The effect of this medicine lasts for an average duration of 3 to 4 days
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit forming tendencies were reported.
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Usage in pregnancy?
This medicine is recommended in pregnant women only if necessary. The benefits and risks should be discussed with the doctor before taking this medicine.
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Usage while breast-feeding?
A small amount of this medicine is known to excreted in breastmilk. It is recommended only if necessary. The benefits and risks should be discussed with the doctor before taking this medicine.
When not to use?
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Allergy
Not recommended in patients with known allergy to Lanoxin Injection 500 mcg 5 Amp .
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Ventricular fibrillation
Not recommended in patients with Ventricular fibrillation.
Warnings
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Pregnancy
This medicine is recommended in pregnant women only if necessary. The benefits and risks should be discussed with the doctor before taking this medicine.
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Breast-feeding
A small amount of this medicine is known to excreted in breastmilk. It is recommended only if necessary. The benefits and risks should be discussed with the doctor before taking this medicine.
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Arrhythmias
There is an increase in the risk of arrhythmia in Lanoxin Injection 500 mcg 5 Amp toxicity patient. This medicine should be used with caution. Close monitoring of blood levels is necessary.
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Sinus Bradycardia and Sino-atrial Block
This medicine may lower the blood pressure and may cause heart block. It is used with caution in patients with heart disease.
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Lanoxin Injection 500 mcg 5 Amp Toxicity
This medicine has an increase in the risk of toxicity due to its narrow therapeutic index. Close monitoring of blood levels is necessary. Any symptoms of anorexia, nausea, vomiting, visual changes and cardiac arrhythmias should be informed to the doctor.
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Acute Myocardial Infarction
This medicine will increase the oxygen demand in myocardial infarction patients. Therefore, it is not recommended in acute myocardial infarction patients.
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Hypocalcemia
Low calcium level in blood will decrease the effect of Lanoxin Injection 500 mcg 5 Amp . Correct the calcium levels before initiating the treatment.
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Hypokalaemia
Low potassium level in blood will increase the concentration of Lanoxin Injection 500 mcg 5 Amp . Correct the potassium levels before initiating the treatment. Any symptoms of diarrhea, vomiting should be reported to the doctor.
Dosage
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Missed Dose
If you miss a dose of Lanoxin Injection 500 mcg 5 Amp , take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
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Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
Interaction with Medicines- Clarithromycin severe
- Pantoprazole moderate
- Atorvastatin moderate
- Calcium gluconate severe
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severe
This medicine is not recommended in patients with bradyarrhythmia/AV block. Inform the doctor if you are having any heart disease. An alternate medicine should be considered based on the clinical condition.
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severe
There is an increase in the risk of Lanoxin Injection 500 mcg 5 Amp toxicity in patients with low potassium and magnesium levels. The baseline of electrolytes should be obtained before initiating the treatment. Close monitoring is necessary.
General Instructions
Take Lanoxin Injection 500 mcg 5 Amp as advised by your doctor. Do not take in larger amounts than advised. It is advised to take this medicine at the same time every day. Monitoring of heart rate and blood pressure is necessary. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor.
Other details
- Can be taken with or without food, as advised by your doctor
- To be taken as instructed by doctor
- May cause sleepiness
References
- webmd.com - Digoxin [Internet]. Available from: https://www.webmd.com/drugs/2/drug-4358/digoxin-oral/details [cited 14/7/2020].
How to use Lanoxin Injection 500 mcg 5 Amp
Administer by direct IV inj slowly over a period of 5 min or longer, given undiluted or diluted with a fourfold or greater volume of SWFI, D5W or NS.
Compatibility: Stable in D5 ½ NS, with KCl 20 mEq, D5W, D10W, LR, 1/2NS, NS and SWFI (when diluted fourfold or greater).
Y-site administration:
Drug to Drug IV Compatibility: Cimetidine, ciprofloxacin, cisatracurium, diltiazem, esmolol, famotidine, fentanyl, heparin, insulin regular, linezolid, meropenem, midazolam, milrinone, morphine, ranitidine.
Drug to Drug IV Incompatibility: Amiodarone, amphotericin B cholesteryl sulphate complex, dobutamine, fluconazole, foscarnet, propofol.
In syringe: Incompatible with doxapram.
When admixed: Incompatible with dobutamine.
Stability: Store at 25°C (77°F); excursions are permitted between 15°C-30°C (59°F-86°F). Protect from light.
what are the adverse effects of Lanoxin Injection 500 mcg 5 Amp?
Usually associated with excessive dosage, include; anorexia, nausea, vomiting, diarrhoea, abdominal pain; visual disturbances, CNS disturbances, headache, fatigue, drowsiness, confusion, delirium, hallucinations, depression, arrhythmias, heart block, PR prolongation, sinus bradycardia, rarely rash, intestinal ischaemia, gynaecomastia on long-term use; thrombocytopenia reported.
What happens if I miss a dose of Lanoxin Injection 500 mcg 5 Amp?
ORAL: Rapid digitalisation, Adults: 1-1.5 mg in divided doses over 24 hr; less urgent digitalisation, Adults: 250-500 mcg daily (higher dose may be divided). Maintenance, 62.5-500 mcg daily (higher dose may be divided) according to renal function and, in atrial fibrillation, on heart-rate response; usual range, 125-250 mcg daily (lower dose may be appropriate in elderly).
INJECTION: Adults: Emergency loading dose by IV infusion, 0.75-1 mg over at least 2 hr, then maintenance dose by mouth on the following day.
Children: Digitalizing Dose: Premature Infants: 20-30 mcg/kg orally or 15-25 mcg/kg IV. Full-Term Infants: 25-35 mcg/kg orally or 20-30 mcg/kg IV. 1-24 mth: 35-60 mcg/kg orally or 30-50 mcg/kg IV. 2-5 yr age: 30-40 mcg/kg orally or 25-35 mcg/kg IV. 5-10 yr age: 20-35 mcg/kg orally or 15-30 mcg/kg IV. Above 10 yr age: 10-15 mcg/kg orally or 8-12 mcg/kg IV. Maintenance: Premature Infants: 20-30% of digitalizing dose. Full-Term Infants to more than 10 yr age: 25-35% of digitalizing dose. 2-5 yr age: 10-15 mcg/kg orally. 5-10 yr age: 7-10 mcg/kg orally. Above 10 yr age: 3-5 mcg/kg.
One of the following licensed pharmacy from the nearest location will deliver Lanoxin Injection 500 mcg 5 Amp. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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