MBBS
Lukodermine 1.00% Topical Oint 30 gm
- Does this requires a prescription ? Yes
- Generic Name: Methoxsalen
- Manufactured by : Lahore Chemical & Pharmaceutical works (PVT) LTD
- Drug Strength : 1.00%
- Drug Form : Topical Oint
- Pack Size : 30 gm
- Product SKU : pu_pg_13557_18785
Lukodermine Topical Oint contains Methoxsalen | belongs to Photosensitizer
Alternate brands of Lukodermine 1.00% Topical Oint 30 gm
Brand Name | Price | Savings |
---|---|---|
Sorolan 1.00% Oint 30 gm | ₨ 61.15 | You can save 63.11 |
Oxsoralen 1.00% Lotion 1 oz | ₨ 672.00 | You will pay -547.74 more |
How it works
Lukodermine 1.00% Topical Oint 30 gm by making the skin more sensitive to UVA light. This combination helps to slow the overgrowth of skin cells.
Uses of Lukodermine 1.00% Topical Oint 30 gm
What is it prescribed for?
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Vitiligo
This medicine is used for the treatment of vitiligo, a skin condition characterized by loss of skin color in patches.
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Psoriasis
This medicine is used for the treatment of psoriasis, a skin disease characterized by excessive scaling, dryness, rashes, and itching of the skin.
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Cutaneous T-cell Lymphoma
This medicine is used to treat cutaneous T-cell lymphoma, a rare type of cancer that begins in the white blood cells and attacks the skin.
Concerns
Frequently asked questions
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Onset of action
The effect of this medicine can be observed within 1 to 3 hours of administration of the dose.
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Duration of Effect
The amount of time for which this medicine remains active is subject to vary based on the dosage form and individual constitution.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit-forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using/receiving this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
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Usage while breast-feeding?
Oral and Extracorporeal dosage forms: This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine. Your doctor may advise you to stop breastfeeding for a specific period of time during treatment with this medicine. Topical forms: This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, care should be taken such that the infant does not come into contact with the medicine.
When not to use?
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Allergy
This medicine is not recommended for use in patients with a known allergy to Lukodermine 1.00% Topical Oint 30 gm , any psoralen compounds, or any other inactive ingredients present along with it.
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Aphakia
This medicine is not recommended for use in patients suffering from aphakia due to the increased risk of worsening of the patient's condition.
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Melanoma
This medicine is not recommended for use in patients with a history of melanoma due to the increased risk of worsening of the patient's condition.
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Squamous Cell Carcinoma
This medicine is not recommended for use in patients with invasive squamous cell carcinomas due to the increased risk of worsening of the patient's condition.
Warnings
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Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using/receiving this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
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Breast-feeding
Oral and Extracorporeal dosage forms: This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine. Your doctor may advise you to stop breastfeeding for a specific period of time during treatment with this medicine. Topical forms: This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, care should be taken such that the infant does not come into contact with the medicine.
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Driving and operating machinery
This medicine may affect the ability to drive and operate machines. Hence, the patient should not drive or operate machines immediately after the treatment.
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Aging of skin and skin burning
After receiving treatment with this medicine and ultra-violet light, further exposure to sunlight and/or ultraviolet radiation may result in premature aging of the skin as well as serious burns. Patients should take all precautionary measures, as advised by the doctor, including covering the skin, using a sun blocking agent, wearing sunglasses, etc. in case they need to go outdoors.
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Carcinogenicity
The use of this medicine and ultraviolet radiation therapy significantly increases the risk of cancer. This risk is especially higher in patients with a previous history of cancer or radiation therapy. All the risks and benefits should be discussed with the doctor before using/receiving this medicine.
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Use in children
This medicine is not recommended for use in patients less than 12 years of age. However, even for patients under the age of 18 years, it should be used only if the benefits significantly outweigh the risks and only under the supervision of a healthcare professional.
Dosage
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Missed Dose
Since this medicine is usually administered in the clinical/hospital setting, the likelihood of a missed dose is very low. However, since this medicine is usually given in multiple cycles, if you miss a scheduled dose of this medicine, call your doctor immediately for further instructions.
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Overdose
Since this medicine is usually administered in the clinical/hospital setting, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
Interactions
Interaction with Medicines- Griseofulvin moderate
- Tizanidine severe
- Tizanidine moderate
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Always take this medicine with milk or low-fat foods to increase tolerability. Avoid eating foods such as limes, figs, parsley, carrots, etc. during treatment with this medicine.
General Instructions
Use/Take this medicine exactly as prescribed by your doctor. Follow all the instructions given on the label/package insert. The oral form of this medicine should be taken with food or milk. Do not sunbathe for 24 hours before using/receiving Lukodermine 1.00% Topical Oint 30 gm and having the UVA light treatment. For 24 hours following the treatment, avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). You are advised to take all precautionary measures such as wearing protective clothing, wearing a sunblock, wearing sunglasses, etc. if you need to go outdoors within 24 hours of therapy.
References
- webmd.com - Methoxsalen [Internet]. Available from: https://www.webmd.com/drugs/2/drug-6957-1257/methoxsalen-oral/methoxsalen-rapid-oral/details [cited 30/7/2020].
- wikipedia.org - Methoxsalen [Internet]. Available from: https://en.wikipedia.org/wiki/Methoxsalen [cited 30/7/2020]. 2020
what are the adverse effects of Lukodermine 1.00% Topical Oint 30 gm?
Oedema, hypotension, nervousness, vertigo, depression, painful blistering, burning, pruritus, hypo-pigmentation, rash, cheilitis, erythema, itching, nausea, loss of muscle coordination.
What happens if I miss a dose of Lukodermine 1.00% Topical Oint 30 gm?
ORAL: Take with milk or after food as a single dose, or in 2 divided doses, approx 30 min apart to minimize GI side effects.
Idiopathic vitiligo: Adults & Children: Above 12 yr: 20 mg/day 2-4 hr before exposure to UVA or sunlight. Therapy should be on alternate days & never on 2 consecutive days. Max dose: 0.6 mg/kg.
Psoriasis: Adults: 10-70 mg, 1.5-2 hr before exposure to UVA, administered 2-3 times wkly.
TOPICAL: Vitiliginous lesions: Adults: The soln/cream after dilution to 0.1% or 0.01% applied once wkly for 6-9 mth. Surrounding skin should be protected by an opaque screen, the treated area should be exposed to UVA after waiting up to 2 hr. After exposure the lesions should be washed and protected from light for up to 48 hr or longer.
Psoriasis: Adults: The preparation is diluted 0.15% (or to 0.015%). Applied to the affected area 15 min before UVA exposure. Alternatively whole body bath or hand/foot soaks given twice a wk have also been recommended (See literature for procedure).
One of the following licensed pharmacy from the nearest location will deliver Lukodermine 1.00% Topical Oint 30 gm. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
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2 reviews for Lukodermine 1.00% Topical Oint 30 gm
Mhaar Jutt –
First Time Use..
Comment After Received My Order.
Toheed Ahmad (verified owner) –
good