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Macartium Forte tablet 80/480 mg 4's

Belongs to Category

Macartium Forte tablet contains Artemether and Lumefantrine | belongs to Artemisinin derivative/Synthetic racemic fluorene mixture

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How it works

Macartium Forte tablet 80/480 mg 4’s medicine works by interfering with certain vital functions in the cell of the malarial parasite present in the blood.

Side effects

Major & minor side effects for Macartium Forte tablet 80/480 mg 4’s

  • Abdominal pain and cramps
  • Nausea and Vomiting
  • Diarrhea
  • Itching and skin rash
  • Hives and wheezing severe
  • Dizziness and lightheadedness
  • Ringing or buzzing in the ears
  • Increased heartbeat severe
  • Elevated liver enzymes severe
  • Muscle and joint pain
  • Sleep disturbances
  • Weight loss severe
  • Shaking and trembling of arms and feet
  • Decrease/loss of hearing severe
  • Uncontrolled eye movements

Uses of Macartium Forte tablet 80/480 mg 4’s

What is it prescribed for?

  • Acute uncomplicated malaria

    This medicine is used to treat acute uncomplicated malaria caused by Plasmodium falciparum strain of the parasite. It may also be used for the treatment of malaria that is resistant to other medicines such as chloroquine or sulphadoxine-pyrimethamine combinations.

Concerns

Frequently asked questions

  • Onset of action

    The initial effect of this medicine can be observed within 2-3 hours of administration.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 3-6 days.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit-forming tendencies were reported.

  • Usage in pregnancy?

    Use of this medicine in pregnant women is not recommended unless absolutely necessary. Your doctor will evaluate all the potential risks and benefits associated with the use of this medicine before prescribing it.

  • Usage while breast-feeding?

    Use of this medicine in breastfeeding women is not recommended unless absolutely necessary. Your doctor will evaluate all the potential risks and benefits associated with the use of this medicine before prescribing it.

When not to use?

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to artemether, lumefantrine, any other artemisinin derivatives, or any other ingredients present in the formulation.

Warnings

Warnings for special population
  • Pregnancy

    Use of this medicine in pregnant women is not recommended unless absolutely necessary. Your doctor will evaluate all the potential risks and benefits associated with the use of this medicine before prescribing it.

  • Breast-feeding

    Use of this medicine in breastfeeding women is not recommended unless absolutely necessary. Your doctor will evaluate all the potential risks and benefits associated with the use of this medicine before prescribing it.

Warnings

Warnings for special population
  • Liver impairment

    This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

  • Kidney impairment

    This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of renal function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

  • Heart diseases

    This medicine should be used with caution in patients suffering from a pre-existing condition of the heart. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

  • Drug resistance

    It is strongly recommended to take this medicine for the entire prescribed duration even when symptoms resolve or improve. Failure to do so might result in parasitic resistance to the drug and treatment of further infection with this medicine would become difficult.

  • Severe complicated malarial infection

    This medicine is not recommended for use if the patient is suffering from a severe and complicated malarial infection.

  • Hormonal contraceptives

    This medicine may alter the effectiveness of hormonal contraceptives. Hence, alternative or additional means of contraception may be necessary based on the clinical condition of the patient.

  • QT prolongation

    This medicine should be used with extreme caution in patients suffering from QT prolongation due to the increased risk of worsening of the patient's condition. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Dosage

  • Missed Dose

    Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

Interaction with Medicines
  • Erythromycin severe
  • Quinidine moderate
  • Chlorpromazine moderate
  • Ciprofloxacin severe
  • Quetiapine severe
  • Terfenadine moderate
  • Doxorubicin severe
  • Doxepin severe
  • Azithromycin severe
  • Citalopram severe
  • Duloxetine moderate
Disease interactions
  • moderate

    This medicine should be administered with caution in patients having an impaired liver function. Appropriate diagnostic tests must be performed before determining the dose regimen. Suitable dose adjustment and frequent monitoring may be needed to ensure safe and effective use.

  • moderate

    This medicine should be administered with caution in patients having an impaired kidney function. Appropriate diagnostic tests must be performed before determining the dose regimen. Suitable dose adjustment and frequent monitoring may be needed to ensure safe and effective use.

General Instructions

Take this medicine with food, as directed by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.

Other details

  • To be taken with food
  • To be taken as instructed by doctor
  • May cause sleepiness

References

what are the adverse effects of Macartium Forte tablet 80/480 mg 4’s

Abdominal pain, anorexia, diarrhoea, vomiting, nausea, palpitation, prolonged QT interval, cough, headache, dizziness, asthaenia, sleep disturbances, paresthesia, arthralgia, myalgia, pruritus, rash.

What is the dose of Macartium Forte tablet 80/480 mg 4’s

CAP/TAB 20/120 mg: Adults: 4 tab as single first dose followed by 4 tab after 8 hr of the 1st dose, 4 tab after 24 hr of the 1st dose and then 48 hr after the 1st dose. (Total course of 16 tab). Children: 5-15 kg body wt: Total course of 4 tab: 1 tab initially followed by 1 tab after 8 hr, after 24 hr and after 48 hr of the 1st dose. 15-25 kg body wt: Total course of 8 tab: 2 tab as a single dose initially followed by dose of 2 tab after 8 hr, after 24 hr and after 48 hr of the 1st dose. 25-35 kg body wt: Total course of 12 tab: 3 tab as a single dose initially followed by dose of 3 tab after 8 hr, after 24 hr and after 48 hr of the 1st dose.
CAP/TAB 40/240 mg: Adults: 2 tab as single first dose followed by 2 tab after 8 hr of the 1st dose, 2 tab after 24 hr of the 1st dose and then 48 hr after the 1st dose. (Total course of 8 tab).
CAP/TAB 80/480 mg: Adults: 1 tab as single first dose followed by 1 tab after 8 hr of the 1st dose, 1 tab after 24 hr of the 1st dose and then 48 hr after the 1st dose. (Total course of 4 tabs).
SUSP: Children: 5-15 kg body wt: Total course of 80 mg (Artemether) & 480 mg (Lumefantrine): 20 mg & 120 mg initially followed by 20 mg & 120 mg after 8 hr, after 24 hr and after 48 hr of the 1st dose. 15-25 kg body wt: Total course of 160 mg & 960 mg: 40 mg & 240 mg as a single dose initially followed by dose of 40 mg & 240 mg after 8 hr, after 24 hr and after 48 hr of the 1st dose. 25-35 kg body wt: Total course of 240 mg & 1440 mg: 60 mg & 360 mg as a single dose initially followed by dose of 60 mg & 360 mg after 8 hr, after 24 hr and after 48 hr of the 1st dose.

One of the following licensed pharmacy from the nearest location will deliver Macartium Forte tablet 80/480 mg 4’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

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