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Information on this page was last modified on : 2019/08/10 6:03:32 PM

Mannitol 10.00% Infusion 500 ml

Mannitol Infusion contains Mannitol, Inf | belongs to Osmotic diuretic

Alternate brands of Mannitol 10.00% Infusion 500 ml

Brand Name Price Savings
Zeesol-M 20.00% Infusion 1000 ml  65.00 You will pay -23.02 more
Zeesol-M 20.00% Infusion 500 ml  28.21 You can save 13.77
Steriflutol 20.00% Infusion 500 ml  124.00 You will pay -82.02 more
Medisol-Mannitol 20.00% Infusion 1000 ml  84.00 You will pay -42.02 more
Medisol-Mannitol 20.00% Infusion 500 ml  119.00 You will pay -77.02 more
List of alternate brands

How it works

Mannitol 10.00% Infusion 500 ml is a polyol (sugar alcohol) with a low molecular weight that is filtered at the glomerulus but not reabsorbed from the renal tubule. It exerts osmotic activity within the proximal convoluted tubule and the descending limb of the loop of Henle, which limits passive tubular reabsorption of water.

Side effects

Major & minor side effects for Mannitol 10.00% Infusion 500 ml

  • Headache
  • Dry mouth
  • Dehydration
  • Fluid and electrolyte imblance severe
  • Chest pain
  • Dizziness
  • Blurred vision severe
  • Nausea
  • Fast or irregular heartbeat rare
  • Reduced food intake rare
  • Uncontrolled shaking of arms or legs rare
  • Urinary incontinence rare

Uses of Mannitol 10.00% Infusion 500 ml

What is it prescribed for?

  • Cerebral edema (Fluid accumulation in cerebral cavity)

    This medicine is used to reduce cerebral edema (brain swelling) by decreasing the intracranial pressure.

  • Oliguria (Low urine output)

    Manilup 20 % Infusion is used to treat oliguria by increasing the urine output.

  • Intraocular pressure (Fluid pressure inside the eye)

    This medicine is used to decrease the fluid pressure inside the eye (intraocular pressure).

Concerns

Frequently asked questions

  • Onset of action

    The estimated amount of time required for this medicine to show its effect is about 1 to 3 hours for diuresis, 30 to 60 minutes for lowering intraocular pressure, and 15 minutes for the reduction of intracranial pressure.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 3 to 8 hours.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendency has been reported.

  • Usage in pregnancy?

    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

  • Usage while breast-feeding?

    This medicine should be used with caution in breastfeeding women. Discuss all the risks and benefits with your doctor before receiving this medicine.

When not to use?

  • Anuria

    This medicine is not recommended for patients with a known history of anuria (a condition where the kidney is unable to produce urine).

  • Severe pulmonary edema (Fluid accumulation in lungs)

    This medicine is not recommended for use in patients with a known history of severe pulmonary edema.

  • Progressive heart failure

    This medicine is not recommended for use in patients with a known history of progressive heart failure caused by Manilup 20 % Infusion therapy.

  • Intracranial bleeding (Bleeding inside the skull)

    Patients with a known history of intracranial bleeding are recommended not to take this medicine.

  • Severe dehydration

    This medicine is not recommended for use in patients with severe dehydration.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

  • Breast-feeding

    This medicine should be used with caution in breastfeeding women. Discuss all the risks and benefits with your doctor before receiving this medicine.

General Warnings
  • Volume and electrolyte depletion

    Manilup 20 % Infusion may alter the blood volume levels and electrolyte levels. This may cause dizziness, dry mouth, and acid-base imbalance. Close monitoring of blood pressure and electrolytes levels is necessary while taking this medicine. Report any symptoms such as weakness, lethargy, muscle pain, drowsiness, dizziness, irregular heartbeat, etc. to the doctor immediately.

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to Manilup 20 % Infusion.

  • Crystallization of solutions

    This medicine may crystallize when exposed to low temperatures. If crystals are visible, they can be dissolved by warming the solution in a hot water bath or a warming cabinet, followed by gentle agitation (shaking of the vial). Once crystals dissolve, allow the solution to cool to room temperature, reinspect for crystals, and use if crystals are not visible. The medicine should not be used if crystals are present. Please note that the method of warming may differ based on the manufacturer's recommendations.

Dosage

  • Missed Dose

    Since this medicine is administered in the clinical/hospital set up by a qualified healthcare professional, the likelihood of a missed dose is very low.

  • Overdose

    Since this medicine is administered in the clinical/hospital set up by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be provided by the doctor if an overdose is suspected.

Interactions

Interaction with Medicines
  • Aminoglycoside antibiotics severe
  • Salbutamol moderate

General Instructions

Manilup 20 % Infusion will be administered by your doctor or a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have an allergy to this medicine. Report all your current medicines as well as your medical history to the doctor. This medicine is usually given at daytime to prevent sleep disturbance. Drink an adequate amount of water. Monitoring of kidney function and electrolytes levels is necessary during treatment with this medicine. This medicine should be used with caution due to the increased risk of dizziness.

Other details

  • Usage does not depend on food timings
  • To be taken as instructed by doctor
  • Does not cause sleepiness

References

Additional Information:

what are the adverse effects of Mannitol 10.00% Infusion 500 ml?

CHF, headache, convulsions, dizziness, rash, electrolyte balance disturbances, hyponatraemia, GI upset, polyurea.

What happens if I miss a dose of Mannitol 10.00% Infusion 500 ml?

Adults: 50-200 gm by IV inf in 24 hr. The rate of administration is usually adjusted to maintain a urine flow of at least 30 to 50 mL per hr.

One of the following licensed pharmacy from the nearest location will deliver Mannitol 10.00% Infusion 500 ml. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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