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Information on this page was last modified on : 2021/04/29 3:14:40 PM

Mediclop Injection 10 mg 10 Ampx2 mL

Mediclop Injection contains Metoclopramide HCl | belongs to Antidopaminergic

Alternate brands of Mediclop Injection 10 mg 10 Ampx2 mL

Brand Name Price Savings
Vomilide Injection 10 mg 10 Ampx2 mL  200.00 You will pay -120 more
Unexolone tablet 10 mg 500’s  467.00 You will pay -387 more
Regelan Injection 10 mg 10 Ampx2 mL  84.24 You will pay -4.24 more
Regelan tablet 10 mg 20’s  7.85 You can save 72.15
Premo Injection 10 mg 10 Ampx2 mL  80.00 You can save 0
List of alternate brands

How it works

It works by increasing the movement of food in the stomach and the intestine.

Side effects

Major & minor side effects for Mediclop Injection 10 mg 10 Ampx2 mL

  • Dizziness severea
  • Abdominal pain severea
  • Convulsions severea
  • Headache severea
  • Skin rash severea
  • Irregular heartbeat severea
  • Diarrhea
  • Restlessness
  • Breast pain and tenderness
  • Increased flow of breast milk

Uses of Mediclop Injection 10 mg 10 Ampx2 mL

What is it prescribed for?

  • Chemotherapy induced nausea and vomiting

    Mediclop Injection 10 mg 10 Ampx2 mL is used to treat nausea and vomiting associated with the use of chemotherapy medicines for the treatment of cancer.

  • Gastroparesis

    Mediclop Injection 10 mg 10 Ampx2 mL is used in the treatment of Gastroparesis since it increases the gastric emptying and prevents nausea and vomiting.

  • Gastroesophageal Reflux Disease

    Mediclop Injection 10 mg 10 Ampx2 mL is used in the treatment of Gastroesophageal Reflux Disease since it increases the gastric emptying and reduces the reflux of gastric contents.

Concerns

Frequently asked questions

  • Onset of action

    The effect of this medicine can be observed in 30 to 60 minutes after an oral dose, 1 to 3 minutes after an intravenous dose, and 10 to 15 minutes after an intramuscular dose.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 1 to 2 hours.

  • Safe with Alchohol?

    Alcohol should not be consumed while receiving this medicine as it may increase the risk of dizziness and lightheadedness. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and Mediclop Injection 10 mg 10 Ampx2 mL are used together.

  • Is it habit forming?

    No habit forming tendency has been reported.

  • Usage in pregnancy?

    This medicine is recommended for use in pregnant women only if necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

When not to use?

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to Mediclop Injection 10 mg 10 Ampx2 mL .

  • Gastrointestinal disorders

    This medicine is not recommended for use in patients with gastrointestinal disorders like gastrointestinal hemorrhage, mechanical obstruction, and gastrointestinal perforation.

  • Seizure disorder

    This medicine is not recommended for use in patients with a known history of seizures.

  • Pheochromocytoma

    This medicine is not recommended for use in patients with conditions like pheochromocytoma due to an increase in the risk of hypertensive crisis (very severe increase in the blood pressure).

Warnings

Warnings for special population
  • Pregnancy

    This medicine is recommended for use in pregnant women only if necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

  • Breast-feeding

    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

General Warnings
  • Neuroleptic Malignant Syndrome (NMS)

    Mediclop Injection 10 mg 10 Ampx2 mL is known to cause Neuroleptic Malignant Syndrome which is characterized by hyperthermia (fever), muscle rigidity, and altered consciousness. Report to the doctor immediately if these symptoms appear. Discontinue Mediclop Injection 10 mg 10 Ampx2 mL treatment if the symptoms persist.

  • Depression

    Mediclop Injection 10 mg 10 Ampx2 mL may cause depression in patients with or without the prior history of depression. Any symptoms of change in behavior or suicidal thoughts should be informed to the doctor on priority. Discontinue the treatment if the symptoms worsen.

Dosage

  • Missed Dose

    The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost the time for the next dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

Interaction with Medicines
  • Phenytoin moderate
  • Atropine moderate
  • Chlorpromazine severe
Disease interactions
  • severe

    Mediclop Injection 10 mg 10 Ampx2 mL is not recommended for use in patients with gastrointestinal disorders like mechanical bowel obstruction, bowel perforation, or gastrointestinal hemorrhage. An alternative treatment option should be considered based on the clinical condition.

  • moderate

    Mediclop Injection 10 mg 10 Ampx2 mL should be used with caution in patients with Parkinson's disease due to an increase in the risk of parkinsonian-like symptoms such as akinesia, bradykinesia, tremors, pill-rolling motion, and postural abnormalities. These symptoms will usually appear within the first 6 months of the treatment and subside within 2 to 3 months after discontinuation of the treatment.

General Instructions

Take Mediclop Injection 10 mg 10 Ampx2 mL as advised by the doctor. Do not take this medicine if you have gastrointestinal disorders like mechanical bowel obstruction, bowel perforation, or gastrointestinal hemorrhage. Monitoring of blood pressure and symptoms like involuntary movements of the tongue, lips, face, and trunk is necessary while consuming this medicine.

Other details

  • To be taken before food
  • To be taken as instructed by doctor
  • May cause sleepiness

References

Additional Information:

How to use Mediclop Injection 10 mg 10 Ampx2 mL

Injection solution may be given IM, direct IV push, short infusion (15-30 min), or continuous infusion; lower doses (=10 mg) of metoclopramide can be given IV push undiluted over 1-2 min; higher doses to be given IVPB over at least 15 min.
Reconstitution: For IV use, doses lt;10 mg do not need dilution. For doses gt;10 mg, dilute in 50 mL 0.9%NS, 0.45% NS, D5W, or lactated Ringer’s solution.
Compatibility: Stable in D5 1/2 NS, LR, NS, mannitol 20%.
Stability: Store at 20°C-25°C (68°F-77°F). Store vials in carton until use. Do not store open single-dose vials for later use, as they contain no preservative. This product is light sensitive. It should be inspected before use and discarded if either colour or particulate is observed. Dilutions may be stored unprotected from light under normal light conditions up to 24 hours after preparation.

what are the adverse effects of Mediclop Injection 10 mg 10 Ampx2 mL?

Extrapyramidal reactions, neuroleptic malignant syndrome. Raised serum prolactin leading to galactorrhoea, irregular periods and gynaecomastia. Drowsiness, diarrhoea, rash, dizziness, tremor, agitation.

What happens if I miss a dose of Mediclop Injection 10 mg 10 Ampx2 mL?

Adults: 20 yr and over: 10 mg three times daily orally, IM or IV. Usual max 0.5 mg/kg body-wt daily.
Children: Second-line option for treatment of established postoperative nausea and vomiting and prevention of delayed chemotherapy-induced nausea and vomiting: ORAL or IM injection, or IV injection over at least 3 minutes: 1-18 yr, 100-150 mcg/kg up to 3 times daily.

One of the following licensed pharmacy from the nearest location will deliver Mediclop Injection 10 mg 10 Ampx2 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

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