₨ 45.66
MBBS
Mesnal Injection 400 mg 1 Amp
- Does this requires a prescription ? Yes
- Generic Name: Mesna
- Manufactured by : Pharmedic Laboratories
- Drug Strength : 400 mg
- Drug Form : Injection
- Pack Size : 1 AMP
- Product SKU : pg_14479_20267
Mesnal Injection contains Mesna | belongs to Uroprotectant
How it works
Mesnal Injection 400 mg 1 Amp binds to the breakdown products of cyclophosphamide and ifosfamide, acrolein, and protects the bladder from its harmful effects.
Side effects
Major & minor side effects for Mesnal Injection 400 mg 1 Amp
- Hypersensitivity severe
- Hypotension severe
- Nausea and vomiting
- Headache
- Blurred vision severe
- Sweating severe
- Loss of appetite severe
- Irregular breathing severe
- Anemia severe
Uses of Mesnal Injection 400 mg 1 Amp
What is it prescribed for?
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Hemorrhagic cystitis prophylaxis
This medicine is used to prevent hemorrhagic cystitis associated with chemotherapy drugs ifosfamide and cyclophosphamide.
Concerns
Frequently asked questions
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Onset of action
The amount of time required for this medicine to show its action is not clinically established.
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Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for use unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
When not to use?
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Hypersensitivity
This medicine is not recommended for use in patients with a known allergy to Mesnal Injection 400 mg 1 Amp or any other components present along with it.
Warnings
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Pregnancy
This medicine is not recommended for use unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
-
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
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Dermatologic toxicity
This medicine may cause Stevens-Johnson Syndrome (SJS) or Toxic Epidermal Necrolysis (TEN) upon first exposure or several months after the exposure. Appropriate corrective measures or discontinuation of therapy may be required based on the clinical condition.
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Laboratory test interferences
This medicine may give false positive results on laboratory tests for vitamin C and urine ketone bodies. It may also give false negative results on laboratory tests for Creatine Phosphokinase (CPK). It is advised that you inform the doctor about treatment with this medicine before undergoing any laboratory tests.
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Adequate hydration
Adequate hydration after treatment with Mesnal Injection 400 mg 1 Amp is recommended to prevent hematuria (blood in urine).
Dosage
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Missed Dose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of missing a dose is very low. However, it is advised to contact the doctor if a dose of Mesnal Injection 400 mg 1 Amp is missed and schedule the dose as soon as possible.
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Overdose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
Interactions
Interaction with Medicines- Warfarin moderate
- Anisindione moderate
-
severe
Caution is advised while administering Mesnal Injection 400 mg 1 Amp to patients with autoimmune disorders due to the increased risk of anaphylactic reactions. This risk is especially higher in patients receiving high oral doses of Mesnal Injection 400 mg 1 Amp . It is advised to monitor the patient for any signs or symptoms such as shortness of breath, skin reactions, swelling of eyes or lips, etc. during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
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severe
The safety and efficacy of Mesnal Injection 400 mg 1 Amp have not been established in pediatric patients. Mesnal Injection 400 mg 1 Amp contains benzyl alcohol as a preservative. Benzyl alcohol has been associated with gasping syndrome and fatalities in premature infants, neonates, low-birth weight infants. Hence, it is advised that practitioners administering this medicine in pediatric patients should take into account the total metabolic load of benzyl alcohol from all sources before initiation of treatment.
General Instructions
This medicine are usually administered by a qualified healthcare professional. Carefully follow all the instructions given by your doctor. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Other details
- Usage does not depend on food timings
- To be taken as instructed by doctor
- May cause sleepiness
References
- dailymed - MESNEX [Internet]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4a51ffdb-f59f-4e02-b3c4-f3457ab7b514 [cited 2/24/2021]. 2019
What happens if I miss a dose of Mesnal Injection 400 mg 1 Amp?
See literature.
One of the following licensed pharmacy from the nearest location will deliver Mesnal Injection 400 mg 1 Amp. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
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There are no answers for this question yet. Answer now
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