₨ 40.00
MBBS
Metharex Injection 25 mg 10 Ampx1 mL
- Does this requires a prescription ? Yes
- Generic Name: Promethazine HCl
- Manufactured by : Rex
- Drug Strength : 25 mg
- Drug Form : Injection
- Pack Size : 10 Ampx1 mL
- Product SKU : pg_14545_20350
Metharex Injection contains Promethazine HCl | belongs to H1 receptor antagonist
Alternate brands of Metharex Injection 25 mg 10 Ampx1 mL
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Semozin Elixir 5 mg/5 mL 450 mL | ₨ 32.00 | You can save 8 |
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Prometh syrup 5 mg/5 mL 450 mL | ₨ 97.65 | You will pay -57.65 more |
Prometh syrup 5 mg/5 mL 120 mL | ₨ 28.35 | You can save 11.65 |
How it works
It works by inhibiting the binding of histamine to its receptor and thus helps in relieving the symptoms.
Uses of Metharex Injection 25 mg 10 Ampx1 mL
What is it prescribed for?
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Allergic reactions
Metharex Injection 25 mg 10 Ampx1 mL is used to treat mild to moderate allergic reactions like urticaria, rhinitis.
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Sedation
Metharex Injection 25 mg 10 Ampx1 mL is used for preoperative, postoperative, and obstetric (during labor) sedation.
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Nausea and vomiting
Metharex Injection 25 mg 10 Ampx1 mL is used to prevent nausea and vomiting in postoperative patients.
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Motion sickness
Metharex Injection 25 mg 10 Ampx1 mL is used to relieve symptoms of motion sickness like nausea and vomiting.
Concerns
Frequently asked questions
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Onset of action
The effect of this medicine can be observed in 20 minutes after an oral dose and 3 to 5 minutes after an intravenous dose.
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Duration of Effect
The effect of this medicine lasts for an average duration of 12 hours.
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Safe with Alchohol?
Consumption of alcohol is not recommended if the patient is receiving Metharex Injection 25 mg 10 Ampx1 mL . Any symptoms of dizziness, difficulty in concentration should be reported to the doctor. Do not perform activities that require mental alertness. An alternate medicine should be considered based on the clinical condition.
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Is it habit forming?
No habit forming tendencies has been reported.
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Usage in pregnancy?
This medicine is not recommended for pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
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Usage while breast-feeding?
This medicine is not recommended in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine. Monitoring of symptoms like excessive sedation and irritability is necessary while breastfeeding.
When not to use?
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Allergy
Not recommended in patients with known allergy to Metharex Injection 25 mg 10 Ampx1 mL .
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Asthma
Not recommended in patients with the history of asthma or any respiratory disease.
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Central nervous system depression
Not recommended in patients with the history of central nervous system depression.
Warnings
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Pregnancy
This medicine is not recommended for pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
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Breast-feeding
This medicine is not recommended in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine. Monitoring of symptoms like excessive sedation and irritability is necessary while breastfeeding.
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Drowsiness
Metharex Injection 25 mg 10 Ampx1 mL should be used with caution due to the risk of drowsiness. Do not perform activities that require mental alertness like driving vehicle and operating machinery. It is advised to take this medicine at bedtime.
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Seizures
Metharex Injection 25 mg 10 Ampx1 mL may lower the seizure threshold. It is used with caution in patients receiving medicines like narcotics or local anesthetic. Any symptoms of seizures should be informed to the doctor. Do not perform activities that require mental alertness like driving vehicle and operating machinery
Dosage
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Missed Dose
The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for the next dose.
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Overdose
Seek emergency medical treatment or contact the doctor in case of overdose.
Interactions
Interaction with Medicines- Escitalopram severe
- Tramadol severe
- Antidiabetic medicines moderate
- Antihypertensives moderate
General Instructions
Take Metharex Injection 25 mg 10 Ampx1 mL as advised by the doctor. Do not take larger amounts that prescribed. Any symptoms like dizziness and difficulty in concentration should be reported to the doctor. Do not perform activities that require mental alertness like driving vehicle and operating machinery.
References
- practo.com - Promethazine [Internet]. Available from: https://www.practo.com/medicine-info/promethazine-232-api [cited 20 september 2019]. 5 Jan 2018
- medlineplus.gov - Promethazine [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a682284.html [cited 20 september 2019]. 11 September 2019
- .medicines.org.uk - Promethazine [Internet]. Available from: https://www.medicines.org.uk/emc/medicine/21162 [cited 20 september 2019]. 15 May 2018
How to use Metharex Injection 25 mg 10 Ampx1 mL
Administer IM into deep muscle mass. IV administration is not preferred route. Solution for injection may be diluted in 25-100 mL NS or D5W (max conc. of 25 mg/mL) and infuse over 15-30 min at a rate of 25 mg/min.
Compatibility: Stable in NS, D5W, D10W, D5NS, LR, 1/2NS, NS.
Stability: Store at controlled room temperature 20°C-25°C (68°F-77°F). Protect from light. Keep covered in carton until time of use. Do not use if solution has developed colour or contains a precipitate.
what are the adverse effects of Metharex Injection 25 mg 10 Ampx1 mL?
Drowsiness, impaired reactions. Dizziness, disorientation, photosensitivity. Extra-pyramidal reactions, convulsions (high doses).
What happens if I miss a dose of Metharex Injection 25 mg 10 Ampx1 mL?
ORAL: Adults: 10-20 mg two or three times daily.
Children: Symptomatic relief of allergy such as hay fever, insomnia associated with urticaria and pruritus: 2-5 yr, 5 mg twice daily or 5-15 mg at night; 5-10 yr, 5-10 mg twice daily or 10-25 mg at night; 10-18 yr, 10-20 mg 2-3 times daily or 25 mg at night increased to 25 mg twice daily if necessary.
Sedation (short-term use): 2-5 yr, 15-20 mg; 5-10 yr, 20-25 mg; 10-18 yr, 25-50 mg.
Sedation in intensive care: 1 mth-12 yr, 0.5-1 mg/kg, max 25 mg, 4 times daily, adjusted according to response; 12-18 yr, 25-50 mg 4 times daily, adjusted according to response.
Nausea and vomiting: The following dose at bedtime on night before travel, repeat following morning if necessary: 2-5 yr, 5 mg; 5-10 yr, 10 mg; 10-18 yr, 20-25 mg.
INJECTION: Adults: IM/IV: Allergic conditions: 25 mg, may be repeated in 2 hr.
Anti-emetic: 12.5-25 mg every 4-6 hr as needed. Sedation: 12.5-25 mg/dose.
Children: IM/IV: Anti-emetic: 0.25-1 mg/kg 4-6 times/day as needed.
Sedation: 0.5-1 mg/kg/dose every 6 hr as needed (max 50 mg/dose).
Sedation in intensive care: 1 mth-12 yr, 0.5-1 mg/kg, max 25 mg, 4 times daily, adjusted according to response; 12-18 yr, 25-50 mg 4 times daily, adjusted according to response.
One of the following licensed pharmacy from the nearest location will deliver Metharex Injection 25 mg 10 Ampx1 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
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1 review for Metharex Injection 25 mg 10 Ampx1 mL
Kamran Kami –
Kamran Kami submitted 5 stars.