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Methazex 25 tablet 25 mg 1000's

Methazex 25 tablet contains Promethazine HCl | belongs to H1 receptor antagonist

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How it works

It works by inhibiting the binding of histamine to its receptor and thus helps in relieving the symptoms.

Side effects

Major & minor side effects for Methazex 25 tablet 25 mg 1000’s

  • Drowsiness severe
  • Headache severe
  • Seizures severe
  • Tremors severe
  • Skin rash
  • Loss of strength
  • Increased sensitivity of the skin to sunlight
  • Excitation

Uses of Methazex 25 tablet 25 mg 1000’s

What is it prescribed for?

  • Allergic reactions

    Methazex 25 tablet 25 mg 1000’s is used to treat mild to moderate allergic reactions like urticaria, rhinitis.

  • Sedation

    Methazex 25 tablet 25 mg 1000’s is used for preoperative, postoperative, and obstetric (during labor) sedation.

  • Nausea and vomiting

    Methazex 25 tablet 25 mg 1000’s is used to prevent nausea and vomiting in postoperative patients.

  • Motion sickness

    Methazex 25 tablet 25 mg 1000’s is used to relieve symptoms of motion sickness like nausea and vomiting.

Concerns

Frequently asked questions

  • Onset of action

    The effect of this medicine can be observed in 20 minutes after an oral dose and 3 to 5 minutes after an intravenous dose.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 12 hours.

  • Safe with Alchohol?

    Consumption of alcohol is not recommended if the patient is receiving Methazex 25 tablet 25 mg 1000’s . Any symptoms of dizziness, difficulty in concentration should be reported to the doctor. Do not perform activities that require mental alertness. An alternate medicine should be considered based on the clinical condition.

  • Is it habit forming?

    No habit forming tendencies has been reported.

  • Usage in pregnancy?

    This medicine is not recommended for pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

  • Usage while breast-feeding?

    This medicine is not recommended in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine. Monitoring of symptoms like excessive sedation and irritability is necessary while breastfeeding.

When not to use?

  • Allergy

    Not recommended in patients with known allergy to Methazex 25 tablet 25 mg 1000’s .

  • Asthma

    Not recommended in patients with the history of asthma or any respiratory disease.

  • Central nervous system depression

    Not recommended in patients with the history of central nervous system depression.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

  • Breast-feeding

    This medicine is not recommended in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine. Monitoring of symptoms like excessive sedation and irritability is necessary while breastfeeding.

Warnings

Warnings for special population
  • Drowsiness

    Methazex 25 tablet 25 mg 1000’s should be used with caution due to the risk of drowsiness. Do not perform activities that require mental alertness like driving vehicle and operating machinery. It is advised to take this medicine at bedtime.

  • Seizures

    Methazex 25 tablet 25 mg 1000’s may lower the seizure threshold. It is used with caution in patients receiving medicines like narcotics or local anesthetic. Any symptoms of seizures should be informed to the doctor. Do not perform activities that require mental alertness like driving vehicle and operating machinery

Dosage

  • Missed Dose

    The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for the next dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of overdose.

Interactions

Interaction with Medicines
  • Escitalopram severe
  • Tramadol severe
  • Antidiabetic medicines moderate
  • Antihypertensives moderate
Disease interactions
  • severe

    Inform the doctor if you have any respiratory disease. This medicine is not recommended due to the risk of respiratory depression. Any symptoms of breathing difficulty should be informed to the doctor.

  • severe

    Inform the doctor if you have any central nervous system disorder or head injury. This medicine is not recommended due to the risk of central nervous system depression. Do not perform activities that require mental alertness.

Lab interactions

General Instructions

Take Methazex 25 tablet 25 mg 1000’s as advised by the doctor. Do not take larger amounts that prescribed. Any symptoms like dizziness and difficulty in concentration should be reported to the doctor. Do not perform activities that require mental alertness like driving vehicle and operating machinery.

Other details

  • To be taken before food
  • To be taken at bedtime only
  • Causes sleepiness

References

How to use Methazex 25 tablet 25 mg 1000’s

Administer IM into deep muscle mass. IV administration is not preferred route. Solution for injection may be diluted in 25-100 mL NS or D5W (max conc. of 25 mg/mL) and infuse over 15-30 min at a rate of 25 mg/min.
Compatibility: Stable in NS, D5W, D10W, D5NS, LR, 1/2NS, NS.
Stability: Store at controlled room temperature 20°C-25°C (68°F-77°F). Protect from light. Keep covered in carton until time of use. Do not use if solution has developed colour or contains a precipitate.

what are the adverse effects of Methazex 25 tablet 25 mg 1000’s

Drowsiness, impaired reactions. Dizziness, disorientation, photosensitivity. Extra-pyramidal reactions, convulsions (high doses).

What is the dose of Methazex 25 tablet 25 mg 1000’s

ORAL: Adults: 10-20 mg two or three times daily.
Children: Symptomatic relief of allergy such as hay fever, insomnia associated with urticaria and pruritus: 2-5 yr, 5 mg twice daily or 5-15 mg at night; 5-10 yr, 5-10 mg twice daily or 10-25 mg at night; 10-18 yr, 10-20 mg 2-3 times daily or 25 mg at night increased to 25 mg twice daily if necessary.
Sedation (short-term use): 2-5 yr, 15-20 mg; 5-10 yr, 20-25 mg; 10-18 yr, 25-50 mg.
Sedation in intensive care: 1 mth-12 yr, 0.5-1 mg/kg, max 25 mg, 4 times daily, adjusted according to response; 12-18 yr, 25-50 mg 4 times daily, adjusted according to response.
Nausea and vomiting: The following dose at bedtime on night before travel, repeat following morning if necessary: 2-5 yr, 5 mg; 5-10 yr, 10 mg; 10-18 yr, 20-25 mg.
INJECTION: Adults: IM/IV: Allergic conditions: 25 mg, may be repeated in 2 hr.
Anti-emetic: 12.5-25 mg every 4-6 hr as needed. Sedation: 12.5-25 mg/dose.
Children: IM/IV: Anti-emetic: 0.25-1 mg/kg 4-6 times/day as needed.
Sedation: 0.5-1 mg/kg/dose every 6 hr as needed (max 50 mg/dose).
Sedation in intensive care: 1 mth-12 yr, 0.5-1 mg/kg, max 25 mg, 4 times daily, adjusted according to response; 12-18 yr, 25-50 mg 4 times daily, adjusted according to response.

One of the following licensed pharmacy from the nearest location will deliver Methazex 25 tablet 25 mg 1000’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

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