₨ 195.90
MBBS
METHOTREXATE 50mg Injection 2ml
- Does this requires a prescription ? Yes
- Generic Name: Methotrexate:50mg
- Manufactured by : Pfizer
- Drug Strength : 50mg
- Drug Form : Injection
- Pack Size : 2ml
- Product SKU : dis_20478
Methotrexate:50mg | Cytotoxic (anti-neoplastic) drugs
Alternate brands of METHOTREXATE 50mg Injection 2ml
| Brand Name | Price | Savings |
|---|---|---|
| METHOTREXATE 50mg Injection 5 Vials | ₨ 1,188.00 | You will pay -992.1 more |
| METHOTREXATE 50mg Injection 20ml | ₨ 1,264.57 | You will pay -1068.67 more |
| METHOTREXATE 50mg Injection 5ml | ₨ 233.28 | You will pay -37.38 more |
| METOTREXATO 50mg Injection Vial | ₨ 225.00 | You will pay -29.1 more |
| EMTHEXATE PF 50mg Injection 2mlx1s | ₨ 220.00 | You will pay -24.1 more |
Manufactured / Marketed By : Pfizer Product Form : InjectionPack Size : 2mlIngredients : Methotrexate:50mgGeneric Category : Cytotoxic (anti-neoplastic) drugs
How it works
METHOTREXATE 50mg Injection 2ml treats cancer by slowing the growth of cancer cells. It treats psoriasis by slowing the growth of skin cells to stop scales from forming.
Side effects
Major & minor side effects for METHOTREXATE 50mg Injection 2ml
- Diarrhea severe
- Joint pain severe
- Abdominal pain severe
- Swelling of feet or lower legs severe
- Dizziness severe
- Fever with chills severe
- Unusual bleeding severe
- Blurred vision severe
- Hair loss
- Loss of appetite
- Nausea or Vomiting
- Pale skin
- Skin rash
- Pain at the injection site
Uses of METHOTREXATE 50mg Injection 2ml
What is it prescribed for?
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Acute Lymphoblastic Leukemia
This medicine is used in the treatment of cancer of the bone marrow that affects the production of white blood cells.
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Choriocarcinoma
This medicine is used for the treatment of cancers that occur in the woman’s uterus.
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Meningeal Leukemia
This medicine is used for the treatment of cancer affecting the meninges which is a thin layer that protects the brain and spinal cord.
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Breast cancer
This medicine is used with other medications in the treatment of breast cancer.
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Psoriasis
This medicine is used for the treatment of severe psoriasis (an autoimmune skin disease characterized by red inflamed skin, often covered by scales) that cannot be controlled by other forms of therapy.
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Rheumatoid Arthritis
This medicine is used alone or with other medications for the treatment of severe rheumatoid arthritis (an autoimmune disease that affects the joints in the body causing pain and swelling) along with rest and physical therapy.
Concerns
Frequently asked questions
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Onset of action
The amount of time required for this medicine to show its action is not clinically established.
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Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.
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Safe with Alchohol?
Consumption of alcohol is not recommended due to the risk of liver injury. Close monitoring of liver enzymes is necessary. Seek immediate medical treatment if any symptoms like lethargy, yellow-colored eyes, and skin, abdominal pain appear.
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Is it habit forming?
No habit forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for pregnant women.
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Usage while breast-feeding?
This medicine is not recommended in breastfeeding women.
When not to use?
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Allergy
This medicine is not recommended for use in patients with a known allergy to METHOTREXATE 50mg Injection 2ml , or any other inactive ingredients present along with the formulation.
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Pregnancy
This medicine is not recommended for use in pregnant women due to the increased risk of birth defects.
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Liver disease
This medicine is not recommended for use in patients with severe liver impairment and alcoholic liver disease due to the increased risk of worsening the patient's condition.
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Blood disorder
This medicine is not recommended for use in patients with blood diseases such as anemia, bone marrow hypoplasia, leukopenia (low white blood cell count), thrombocytopenia (low platelet count), etc. due to the increased risk of worsening the patient's condition.
Warnings
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Pregnancy
This medicine is not recommended for pregnant women.
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Breast-feeding
This medicine is not recommended in breastfeeding women.
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Bonemarrow suppression
This medicine should be used with extreme caution in patients having conditions like thrombocytopenia, agranulocytosis, anemia, or bone marrow suppression due to the increased risk of worsening of the patient's condition. A complete blood count should be performed before initiating treatment with this medicine. Close monitoring of blood counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
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Driving or operating machinery
Use of this medicine may cause dizziness, tiredness, drowsiness, blurred vision, etc. in some patients. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you experience any of these symptoms during treatment with this medicine.
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Lung toxicity
This medicine may cause severe lung injuries like pulmonary fibrosis, pulmonary interstitial infiltrates. Any symptoms of breathing difficulty and signs of lung impairment should be informed to the doctor. The treatment should be discontinued if any symptoms appear.
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Skin reactions
The medicine may cause severe skin reactions such as stevens-johnson syndrome, skin necrosis, and skin ulceration. Inform the doctor if any symptoms appear. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.
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Gastrointestinal injury
This medicine should be used with extreme caution in patients suffering from gastrointestinal disorders such as peptic ulcer disease or ulcerative colitis due to the increased risk of worsening of the patient's condition. Inform the doctor if you have any gastrointestinal disorders before initiation of the therapy. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.
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Infections
Use of this medicine may weaken the immune system and make you more vulnerable to infections. It is advised that you avoid coming in contact with people suffering from an infection while receiving this medicine. Any signs and symptoms of infection such as a sore throat, fever, chills, etc. should be reported to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.
Dosage
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Missed Dose
Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. However, it is advised to contact the doctor immediately if you miss a scheduled dose of this medicine.
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Overdose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
Interactions
Interaction with Medicines- Azole antifungal agents moderate
- Atorvastatin moderate
- Live attenuated vaccines and related products severe
- Proton pump inhibitors severe
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severe
This medicine is not recommended for use in patients with severe liver impairment and alcoholic liver disease due to the increased risk of worsening the patient's condition. An alternative treatment option should be considered based on the clinical condition.
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severe
This medicine should be used with extreme caution in patients suffering from kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
General Instructions
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Other details
- Usage does not depend on food timings
- To be taken as instructed by doctor
- May cause sleepiness
References
- medlineplus.gov - Methotrexate [Internet]. Available from: https://medlineplus.gov/druginfo/meds/a682019.html [cited 20/7/2020]. 2020
One of the following licensed pharmacy from the nearest location will deliver METHOTREXATE 50mg Injection 2ml. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
Questions and Answers
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