Midazom Injection 5 mg 5 Ampx5 mL

 347.00

Manufactured by:
Active Pharmaceutical Ingredient:
Drug Strength: 5 mg
Drug Form : Injection
Pack Size : 5 Ampx5 mL

Midazom Injection contains Midazolam | belongs to Benzodiazepine

SKU: pg_14758_20610 Categories: , ,

Alternate brands of Midazom Injection 5 mg 5 Ampx5 mL

Brand Name Price Savings
Xepulse tablet 7.5 mg 10’s  90.00 You can save 257
Surgisafe tablet 7.5 mg 10’s  50.00 You can save 297
Sedazolam Injection 5 mg 1 Ampx5 mL  280.41 You can save 66.59
Noctrum Injection 5 mg 5 Ampx5 mL  225.00 You can save 122
Mizam tablet 7.5 mg 10’s  40.00 You can save 307
List of alternate brands

Reviews

There are no reviews yet.

Be the first to review “Midazom Injection 5 mg 5 Ampx5 mL”

How it works

Midazom Injection 5 mg 5 Ampx5 mL minimizes the activity in the brain and induces relaxation, drowsiness, and sleep.

Side effects

Major & minor side effects for Midazom Injection 5 mg 5 Ampx5 mL

  • Anxiety severe
  • Chest pain and discomfort severe
  • Confusion severe
  • Drowsiness severe
  • Irregular heart beat severe
  • Irritability severe
  • Nausea and Vomiting severe
  • Nervousness
  • Shortness of breath
  • Rash

Uses of Midazom Injection 5 mg 5 Ampx5 mL

What is it prescribed for?

  • Light Sedation

    This medicine is used before medical procedures to sedate and relieve anxiety.

  • Light Anesthesia

    This medicine is administered prior to general anesthetic agents to cause drowsiness and relieve anxiety.

  • Insomnia

    This medicine is used for the short-term treatment of insomnia.

  • Seizures

    This medicine is used for the emergency treatment of seizures.

Concerns

Frequently asked questions

  • Onset of action

    The time required for this medicine to show its action is about 10 to 20 minutes by the intramuscular, intranasal, and oral administration and about 3 to 5 minutes by intravenous administration.

  • Duration of Effect

    This medicine remains active in the body for about 2 to 6 hours.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    This medicine may become habit forming in some cases. Close monitoring of the patient for any changes in behavior or mood is recommended during treatment with this medicine.

  • Usage in pregnancy?

    This medicine is not recommended for use in pregnant women unless absolutely necessary. Discuss all the risks and benefits with your doctor before receiving this medicine.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before receiving this medicine.

When not to use?

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to Midazom Injection 5 mg 5 Ampx5 mL any other ingredients present along with it.

  • Acute narrow-angle glaucoma

    This medicine is not recommended for use in patients with a known history of acute narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use in pregnant women unless absolutely necessary. Discuss all the risks and benefits with your doctor before receiving this medicine.

  • Breast-feeding

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before receiving this medicine.

General Warnings
  • Respiratory distress

    This medicine should be used with caution in patients with a known history of lung diseases due to the increased risk of worsening of the patient's condition.

  • Use in shock/coma/depressed respiration

    This medicine should not be used in patients suffering from shock, coma, or depressed respiration due to the increased risk of worsening of the patient's condition.

  • Paradoxical reactions

    This medicine should be used with caution due to the increased risk of paradoxical reactions. These may include excitability, nervousness, hostility, nightmares, sleep disturbances, etc. This risk is especially higher in patients with psychiatric disorders. Close monitoring of the patient for any changes in mood and behavior is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

  • Impaired kidney and liver function

    This medicine should be used with caution in patients with impaired kidney and/or liver function due to the increased risk of severe side effects.

  • Myasthenis gravis

    Midazom Injection 5 mg 5 Ampx5 mL should be used with caution in patients with myasthenia gravis due to the increased risk of worsening of the patient's condition.

Dosage

  • Missed Dose

    Tablets: If the tablets are used for insomnia, take the missed dose as soon as you remember. It is advisable to skip the missed dose if it is already daytime. Try not to miss any dose as the quantity and timings are very specific and non-adherence could cause some side effects. Injection/Syrup/Nasal spray/Tablets: Since this medicine is given by a qualified healthcare professional either in emergency situations or preoperatively, the likelihood of missing a dose is very low.

  • Overdose

    Tablets used for insomnia: Seek emergency medical treatment or contact the doctor in case of an overdose. Injection/Syrup/Nasal Spray/Tablets: Since this medicine is administered either in emergency situations or preoperatively by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose of this medicine is suspected.

Interactions

Interaction with Medicines
  • Amitriptyline moderate
  • Clozapine severe
  • Fluconazole severe
  • Atazanavir severe
  • Darunavir severe
Disease interactions
  • severe

    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects such as drowsiness, dizziness, lightheadedness, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you consume alcohol while taking Midazom Injection 5 mg 5 Ampx5 mL .

  • severe

    This medicine should be used with extreme caution in patients with a known history of respiratory depression due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be required based on the clinical condition of the patient.

  • severe

    This medicine is not recommended for use in patients with a known history of closed-angle glaucoma due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be required based on the clinical condition.

  • severe

    This medicine should be used with caution in patients with a known history of congestive heart failure due to the increased risk of worsening of the patient's condition. Any unusual symptoms should be reported to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

  • severe

    This medicine should be used with caution in patients with a known history of depression due to the increased risk of worsening of the patient's condition. Patients should be monitored closely for any change in behavior or mood. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

  • severe

    This medicine should be used with caution in obese patients due to the increased risk of severe side effects. Any unusual symptoms should be reported to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Food interactions
  • Consumption of grapefruit or grapefruit juice is not recommended during treatment with this medicine due to the increased risk of serious and life-threatening reactions.

General Instructions

Tablets: Take Midazom Injection 5 mg 5 Ampx5 mL as instructed by the doctor. Your dose is likely to be changed by the doctor during the course of treatment and hence all changes should be properly followed. Do not consume this medicine in larger or smaller quantities than prescribed. You are likely to experience some side effects whenever there is a change in dose quantity or timings. The usage should be stopped gradually over time as instructed. Injection/Syrup/Nasal Spray: This medicine is usually administered by a qualified healthcare professional. Follow all the instructions given by your doctor.

Other details

  • Usage does not depend on food timings
  • To be taken as instructed by doctor
  • Causes sleepiness

References

Additional Information>

How to use Midazom Injection 5 mg 5 Ampx5 mL

IM: Give deep IM into large muscle. IV: Administer by slow IV injection over at least 2-5 min at a concentration of 1-5 mg/mL or by IV infusion. Continuous infusions should be administered via an infusion pump.
Compatibility: Stable in D5NS, D5W, NS. Incompatible with LR.
Y-site administration:
Drug to Drug IV Compatibility: Amikacin, amiodarone, aztreonam, calcium gluconate, cephazolin, ceftriaxone, cimetidine, ciprofloxacin, cisatracurium, digoxin, diltiazem, diphenhydramine, dopamine, enalapril, epinephrine, esmolol, famotidine, fentanyl, fluconazole, gentamicin, heparin, hydromorphone, labetalol, levofloxacin, linezolid, lorazepam, magnesium sulphate, methylprednisolone, metoclopramide, metronidazole, milrinone, morphine, nitroglycerin, nitroprusside, norepinephrine, ondansetron, phenylephrine, ranitidine, tobramycin, vancomycin, vasopressin, vecuronium.
Drug to Drug IV Incompatibility: Acyclovir, amphotericin B cholesteryl sulphate complex, ampicillin, bumetanide, butorphanol, cefepime, ceftazidime, cefuroxime, clonidine, co-trimoxazole, dexamethasone sodium succinate, dobutamine, floxacillin, foscarnet, fosphenytoin, furosemide, hydrocortisone sodium succinate, imipenem/cilastatin, lansoprazole, methotrexate, nafcillin, omeprazole, pantoprazole, sodium bicarbonate, thiopental.
In syringe: Incompatible with dimenhydrinate, pentobarbital, perphenazine, prochlorperazine edisylate, ranitidine.
Stability: Reconstituted solution at a final concentration of 0.5 mg/mL, is stable for up to 24 hours when diluted with D5W or NS.

UNLICENSED USE
Adults: Status epilepticus refractory to standard therapy: Intubation required; adjust dose based on hemodynamics, seizure activity and EEG. IV: 0.15-0.3 mg/kg (usual dose: 5-15 mg); may repeat every 10-15 minutes as needed.
Status epilepticus, prehospital treatment: Administered by paramedics when convulsions last gt;5 minutes or if convulsions are occurring after having intermittent seizures without regaining consciousness for gt; 5 minutes. IM: 10 mg once.
Children: Status epilepticus, febrile convulsions: IV: Neonate, initially by IV injection 150-200 mcg/kg followed by continuous IV infusion of 60 mcg/kg/hr (increased by 60 mcg/kg/hr every 15 minutes until seizure controlled), max. 300 mcg/kg/hr; 1 mth-18 yr, initially by IV injection 150-200 mcg/kg followed by continuous IV infusion of 60 mcg/kg/hr (increased by 60 mcg/kg/hr every 15 minutes until seizure controlled), max 300 mcg/kg/hr.

what are the adverse effects of Midazom Injection 5 mg 5 Ampx5 mL?

Confusion, euphoria, hallucinations, headache, dizziness, ataxia, anterograde amnesia, paradoxical reactions, convulsions, GI upset, cardiorespiratory depression, hypotension, rash, slight tachycardia, vasodilation, dyspnoea, erythema, thrombophlebitis, thrombosis, pain at injection site. Paradoxical reactions, anterograde amnesia. Tolerance and dependence may develop during long-term sedation. Judgement and dexterity may be impaired; warn patient.

What happens if I miss a dose of Midazom Injection 5 mg 5 Ampx5 mL?

Adults: The dose needs to be individualized based on the patient’s age, underlying diseases and concurrent medications. Consider reducing dose by 20% to 50% in elderly, chronically ill, or debilitated patients and those receiving opioids or other CNS depressants.
Preoperative/preprocedural sedation: Healthy adults lt; 60 yr: IM: 0.07-0.08 mg/kg 30-60 minutes prior to surgery/procedure, usual dose 5 mg. IV: 0.02-0.04 mg/kg, repeat every 5 minutes as needed to desired effect or up to 0.1-0.2 mg/kg.
Conscious sedation: IV: Healthy adults lt; 60 yr: Initial 1 mg; no more than 2.5 mg over a period of 2 minutes. Additional doses after 2 minutes if necessary. Total dose above 5 mg is generally not needed. Maintenance 25% of dose used to reach sedative effect. Above 60 yr age, consider dose reduction as for elderly as mentioned below.
Anaesthesia: IV: Induction: Adults lt; 55 yr: Patients without premedication: 0.3-0.35 mg/kg over 20-30 sec; after 2 minutes, may repeat if necessary at 25% of initial dose every 2 minutes, up to a total dose of 0.6 mg/kg in resistant cases. Premedicated patients: Usual dosage range: 0.05-0.2 mg/kg, usually 0.2 mg/kg over 5-10 sec. When used with other anaesthetic drugs (co-induction), the dose is lt;0.1 mg/kg. Maintenance: 0.05 mg/kg as needed, or continuous infusion 0.015-0.06 mg/kg/hr (0.25-1 meg/kg/minute).
Sedation in mechanically-ventilated patients: IV: Initial dose: 0.01-0.05 mg/kg (0.5-4 mg); may repeat at 5 to 15 minutes intervals until adequate sedation; maintenance infusion, 0.02-0.1 mg/kg/hr (0.3-1.7 meg/kg/minute). Titrate to reach desired level of sedation. Elderly: Anaesthesia: IV: Induction: Adults gt;55 yr: Patients without premedication: Initial dose: 0.3 mg/kg. Premedicated patients: Reduce dose by at least 20%.
Elderly: Conscious sedation: IV: Initial: 0.5 mg slow IV; give no more than 1.5 mg in a 2 minute period; if additional titration is needed, give no more than 1 mg over 2 minutes, waiting another 2 or more minutes to evaluate sedative effect, a total dose of gt;3.5 mg is rarely necessary.
Elderly: Preoperative/preprocedural sedation: gt;60 yr (without concomitant opioid administration): IM: 2-3 mg (or 0.02-0.05 mg/kg) 30-60 minutes prior to surgery/procedure; some may only require 1 mg (or 0.01 mg/kg) if anticipated intensity and duration of sedation is less critical.
Children: Not recommended for children under 6 mth for premedication and conscious sedation; not recommended for oral use or by buccal administration for conscious sedation. Oromucosal solution not recommended for children under 3 mth; injection not recommended for status epilepticus or febrile convulsions.
Conscious sedation for procedures: ORAL: 1 mth-18 yr, 500 mcg/kg, max 20 mg, 30-60 minutes before procedure. By buccal administration: 6 mth-10 yr, 200-300 mcg/kg, max 5 mg; 10-18 yr, 6-7 mg, max 8 mg if 70 kg or over. By RECTUM: 6 mth-12 yr, 300-500 mcg/kg 15-30 minutes before procedure. IV INJECTION over 2-3 minutes 5-10 minutes before procedure: 1 mth-6 yr, initially 25-50 mcg/kg, increased if necessary in small steps, max total dose 6 mg; 6-12 yr, initially 25-50 mcg/kg, increased if necessary in small steps, max total dose 10 mg; 12-18 yr, initially 25-50 mcg/kg, increased if necessary in small steps, max total dose 7.5 mg.
Premedication: ORAL: 1 mth-18 yr, 500 mcg/kg, max 20 mg, 15-30 minutes before the procedure. By RECTUM: 6 mth-12 yr, 300-500 mcg/kg 15-30 minutes before induction.
Induction of anaesthesia (but rarely used): IV INJECTION: 7-18 yr, initially 150 mcg/kg, max 7.5 mg, given in steps of 50 mcg/kg, max 2.5 mg, over 2-5 minutes; wait for 2-5 minutes then give additional doses of 50 mcg/kg, max 2.5 mg, every 2 minutes if necessary, max total dose 500 mcg/kg (not exceeding 25 mg).
Sedation in intensive care: IV injection and continuous IV infusion: Neonate less than 32 wk corrected gestational age, 60 mcg/kg/hr by continuous IV infusion, reduced after 24 hr to 30 mcg/kg/hr; adjusted according to response, max treatment duration 4 days; Neonate over 32 wk corrected gestational age, 60 mcg/kg/hr by continuous IV infusion adjusted according to response, max treatment duration 4 days; 1-6 mth, 60 mcg/kg/hr by continuous IV infusion adjusted according to response; 6 mth-12 yr, initially 50-200 mcg/kg by slow IV injection over at least 3 minutes followed by 30-120 mcg/kg/hr by continuous IV infusion adjusted according to response; 12-18 yr, initially 30-300 mcg/kg by slow IV injection given in steps of 1-2.5 mg every 2 minutes followed by 30-200 mcg/kg/hr by continuous IV infusion adjusted according to response.
Status epilepticus, febrile convulsions: By buccal administration, the following dose repeated once after 10 minutes if necessary: Neonate, 300 mcg/kg; 1-3 mth, 300 mcg/kg, max 2.5 mg; 3 mth-1 yr, 2.5 mg; 1-5 yr, 5 mg; 5-10 yr, 7.5 mg; 10-18 yr, 10 mg.

One of the following licensed pharmacy from the nearest location will deliver Midazom Injection 5 mg 5 Ampx5 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.

Questions and Answers

There are no questions yet. Be the first to ask a question about this product.

Only registered users are eligible to enter questions

Shopping Cart

Medicalstore.com.pk © All rights reserved

Made with ❤ by Dairah