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Nicocin capsule 500 mg 12's

Nicocin capsule contains Lincomycin | belongs to Lincosamide

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How it works

It works by inhibiting the protein synthesis which is essential for the bacteria to grow.

Side effects

Major & minor side effects for Nicocin capsule 500 mg 12’s

  • Abdominal pain
  • Diarrhea
  • Dizziness when getting up suddenly from a sitting position
  • Fast heartbeat
  • Skin rash and itching
  • Yellow colored eyes or skin
  • Ringing or buzzing in the ears
  • Hearing impairment
  • Pain at the injection site

Uses of Nicocin capsule 500 mg 12’s

What is it prescribed for?

  • Bacterial infections

    Nicocin capsule 500 mg 12’s is used in the treatment of severe infections caused by streptococci, pneumococci, and staphylococci bacteria.

Concerns

Frequently asked questions

  • Onset of action

    The peak levels of this medicine can be observed in 2 to 4 hours after an oral dose and 30 to 60 minutes after an intramuscular dose.

  • Duration of Effect

    The effect of this medicine lasts for an average duration of 12 to 24 hours.

  • Safe with Alchohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    No habit forming tendency has reported.

  • Usage in pregnancy?

    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

  • Usage while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

When not to use?

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to Nicocin capsule 500 mg 12’s or Clindamycin.

Warnings

Warnings for special population
  • Pregnancy

    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

  • Breast-feeding

    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Warnings

Warnings for special population
  • Clostridium difficile-associated Diarrhea

    Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of bacteria called Clostridium difficile and you may experience severe diarrhoea as a result. Report any such incidence to the doctor on priority and avoid usage of Nicocin capsule 500 mg 12’s in such cases.

  • Gasping syndrome

    Benzyl alcohol which is an ingredient of the Nicocin capsule 500 mg 12’s injection has been associated with "Gasping Syndrome" in paediatrics patients, which is characterised by multi-system failure. The risk depends on the quantity administered and the liver function. Premature and low-birth-weight infants are at increased risk of developing the gasping syndrome.

  • Liver and kidney disease

    Nicocin capsule 500 mg 12’s should be used with caution in patients with liver and kidney disease. The dose should be reduced to 25% to 30% of the normal dosage in severe kidney disease conditions (CrCl less than 10 mL/min). Close monitoring of kidney and liver function is necessary while receiving this medicine.

Dosage

  • Missed Dose

    The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost the time for your next dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

Interaction with Medicines
  • Erythromycin moderate
  • Ethinyl Estradiol This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
  • Live attenuated vaccines and related products severe
Disease interactions
  • Information not available.

Lab interactions

General Instructions

Take Nicocin capsule 500 mg 12’s as instructed by the doctor. Do not take larger quantities than prescribed. It should be used only in severe infectious conditions. Discontinue the medicine if persistent diarrhoea occurs. Close monitoring of liver and kidney function is necessary while receiving the medicine.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • Does not cause sleepiness

References

How to use Nicocin capsule 500 mg 12’s

IV: 1 gm Lincomycin diluted in not less than 100 mL of appropriate solution and infused over a period of not less than one hour.
Reconstitution: Dilute 600 mg dose in at least 100 mL D5W, D10W, NS, dextrose 5% in NS, or other compatible diluent. Dilute higher doses in 100 mL of a compatible diluent for each gm being given.
Compatibility: D5W D10W, D5NS, D10NS. Ringer’s sol. Incompatible with novobiocin and kanamycin.
Stability: Store at 20°C-25°C (68°F-77°F). Diluted lincomycin in an appropriate solution is physically compatible for 24 hours at room temperature unless otherwise indicated.

what are the adverse effects of Nicocin capsule 500 mg 12’s

Persistent diarrhoea, colitis; discontinue immediately.

What is the dose of Nicocin capsule 500 mg 12’s

CAPSULE: Adults: 500 mg three or four times daily.
SYP/SUSP: Children: Under 1 mth, not recommended; 1-6 mth, 1.25-2.5 mL three times daily; 6 mth-2 yr, 2.5-5 mL three times daily; 3-9 yr; 2.5-5 mL four times daily; 10-12 yr, 5-10 mL four times daily.
INJECTION: Adults: 600 mg by IM inj 12-24 hrly or IV infusion 8-12 hrly. Children: Under 1 mth, not recommended; others, 10 mg/kg by IM inj 12-24 hrly; alternatively 10-20 mg/kg daily by IV infusion in 2 or 3 divided doses at 8-12 hr intervals.

One of the following licensed pharmacy from the nearest location will deliver Nicocin capsule 500 mg 12’s. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability.

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