₨ 725.00
MBBS
Ondavell Injection 4 mg 5 Ampx2 mL
- Does this requires a prescription ? Yes
- Generic Name: Ondansetron
- Manufactured by : Icon
- Drug Strength : 4 mg
- Drug Form : Injection
- Pack Size : 5 Ampx2 mL
- Product SKU : pg_17017_23571
Ondavell Injection contains Ondansetron | belongs to 5HT3-antagonist
Alternate brands of Ondavell Injection 4 mg 5 Ampx2 mL
Brand Name | Price | Savings |
---|---|---|
Zofran Injection 8 mg 5 Ampx4 mL | ₨ 4,525.66 | You will pay -3800.66 more |
Zofran tablet 8 mg 10’s | ₨ 3,795.79 | You will pay -3070.79 more |
Setron tablet 8 mg 10’s | ₨ 1,500.00 | You will pay -775 more |
Preset tablet 8 mg 10’s | ₨ 860.00 | You will pay -135 more |
Osetron tablet 8 mg 10’s | ₨ 1,429.37 | You will pay -704.37 more |
How it works
Ondavell Injection 4 mg 5 Ampx2 mL blocks the action of chemicals (serotonin) in the body that can trigger nausea and vomiting.
Side effects
Major & minor side effects for Ondavell Injection 4 mg 5 Ampx2 mL
- Headache severe
- Constipation severe
- Fatigue severe
- Painful urination severe
- Fever
- Dry mouth
- Anxiety
Uses of Ondavell Injection 4 mg 5 Ampx2 mL
What is it prescribed for?
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Nausea and vomiting
Ondavell Injection 4 mg 5 Ampx2 mL is used to treat nausea and vomiting.
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Chemotherapy induced nausea and vomiting
Ondavell Injection 4 mg 5 Ampx2 mL is used to treat nausea and vomiting in cancer chemotherapy patients.
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Post operative nausea and vomiting
Ondavell Injection 4 mg 5 Ampx2 mL is used to treat nausea and vomiting in post-operative patients
Concerns
Frequently asked questions
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Onset of action
The peak effect of Ondavell Injection 4 mg 5 Ampx2 mL can be observed within 30 minutes for Intravenous and 2 hours for the tablet.
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Duration of Effect
This medicine is excreted primarily in urine and the effect of this medicine lasts for a duration of 12 to 28 hours.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit forming tendency has been reported.
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Usage in pregnancy?
Use of Ondavell Injection 4 mg 5 Ampx2 mL is not recommended in pregnant women.
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Usage while breast-feeding?
No clear data is available whether Ondavell Injection 4 mg 5 Ampx2 mL is excreted through human breast milk. So, use of this drug is not recommended in breastfeeding women.
When not to use?
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Allergy
Avoid if the patient has a known allergy to Ondavell Injection 4 mg 5 Ampx2 mL .
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Apomorphine
Avoid using Ondavell Injection 4 mg 5 Ampx2 mL with Ondavell Injection 4 mg 5 Ampx2 mL as it increases the risk of lightheadedness and loss of consciousness.
Warnings
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Pregnancy
Use of Ondavell Injection 4 mg 5 Ampx2 mL is not recommended in pregnant women.
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Breast-feeding
No clear data is available whether Ondavell Injection 4 mg 5 Ampx2 mL is excreted through human breast milk. So, use of this drug is not recommended in breastfeeding women.
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Hypersentivity
Avoid if the patient has a known allergy to Ondavell Injection 4 mg 5 Ampx2 mL .
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Liver disease
Avoid using if the patient is having any liver disease as there are reports of Ondavell Injection 4 mg 5 Ampx2 mL increasing patient's liver enzymes.
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Paediatics
Avoid using in children who are younger than 4 years.
Dosage
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Missed Dose
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Overdose
Seek emergency medical attention or contact the doctor in case of overdose.
Interactions
Interaction with Medicines- Amitriptyline severe
- Carbamazepine moderate
- Phenytoin moderate
- Amiodarone severe
- Apomorphine severe
- Cyclophosphamide moderate
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severe
Details of any heart disease, family history of an arrhythmia or any other drugs that cause QT interval prolongation (eg: Antipsychotics, Arrhythmia drugs) should be reported to the doctor. Regular cardiac function tests are to be performed if the patient is having any heart disease.
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moderate
Details of any liver disease (jaundice, hepatitis) or other drugs that may affect the liver (eg: TB drugs, HIV drugs) should be reported to the doctor. Regular liver function tests are to be performed if the patient is having any liver disease.
General Instructions
Take Ondavell Injection 4 mg 5 Ampx2 mL with or without food. Do not take in larger amounts than advised. Consult the doctor if the patient experiences any undesirable effects.
Other details
- Food timings: Information not available
- Administration time: Information not available
- Sleep inducing: Information not available
References
- practo.com - Ondansetron [Internet]. Available from: https://www.practo.com/medicine-info/ondansetron-211-api [cited 1 0ctober 2019]. 6 Mar 2017
- drugs.com - Ondansetron [Internet]. Available from: https://www.drugs.com/ondansetron.html [cited 1 0ctober 2019]. 1 Aug 2019
- medicines.org.uk - Ondansetron [Internet]. Available from: https://www.medicines.org.uk/emc/medicine/28489#PRODUCTINFO [cited 1 0ctober 2019]. 06 Sep 2018
How to use Ondavell Injection 4 mg 5 Ampx2 mL
IM: Should be given undiluted. IV: Give first dose 30 min prior to beginning chemotherapy; the IV preparation has been successful when administered orally. IVPB: Infuse over 15-30 min; 24-hour continuous infusions have been reported, but are rarely used.
Reconstitution: Prior to IV infusion, dilute in 50-100 mL D5W or NS.
Compatibility: Stable in D5 ½ NS, D5NS, D5W, mannitol 10%, LR, NS, NS 3%. Do not mix injection with alkaline solutions.
Y-site administration:
Drug to Drug IV Compatibility: Amikacin, azithromycin, aztreonam, bumetanide, calcium gluconate, cephazolin, cimetidine, ciprofloxacin, cisatracurium, dexamethasone, diltiazem, diphenhydramine, dobutamine, dopamine, enalapril, epinephrine, esmolol, famotidine, fentanyl, fluconazole, gentamicin, heparin, hydrocortisone, hydromorphone, imipenem, labetalol, levofloxacin, linezolid, magnesium sulphate, metoclopramide, midazolam, morphine, nitroglycerin, nitroprusside, norepinephrine, phenylephrine, piperacillin/tazobactam, propofol, ranitidine, tobramycin, vancomycin, vasopressin.
Drug to Drug IV Incompatibility: Acyclovir, allopurinol, aminophylline, amphotericin B, ampicillin, ampicillin/sulbactam, cefepime, cefoperazone, furosemide, ganciclovir, lansoprazole, lorazepam, meropenem, methylprednisolone, pantoprazole, sodium succinate, piperacillin, sodium bicarbonate.
Stability: Store vials between 2°C-30°C. Protect from light. Stable when mixed in 5% dextrose or 0.9% NaCl for 48 hours at room temperature.
what are the adverse effects of Ondavell Injection 4 mg 5 Ampx2 mL?
Constipation, headache, flushing. Transient rise in liver enzymes. Rarely hypersensitivity reactions, anaphylaxis, chest pain, ST segment depression, cardiac arrhythmia, hypotension, bradycardia, extrapyramidal reactions, seizures, visual disturbance.
What happens if I miss a dose of Ondavell Injection 4 mg 5 Ampx2 mL?
Adults: Chemotherapy and radiotherapy: Highly emetogenic regimens: Single dose of 8 mg by slow IV inj immediately prior to chemotherapy; or 8 mg by slow IV inj prior to chemotherapy followed by either two doses of 8 mg by IV inj repeated 2-4 hr apart or by 1 mg per hr by IV infusion for up to 24 hr; or single dose of 32 mg in 50-100 mL saline infused over 15 min prior to chemotherapy. After first 24 hrs, follow by 8 mg orally twice daily for up to 5 days. Efficacy may be enhanced by addition of dexamethasone 20 mg IV prior to chemotherapy.
Less emetogenic regimens: 8 mg by slow IV inj immediately prior to chemotherapy, or orally 1-2 hr before, followed by 8 mg orally twelve hrly. After first 24 hrs, follow by 8 mg orally twice daily for up to 5 days.
Postoperative prophylaxis: 8 mg orally 1 hr prior to anaesthesia followed by two doses of 8 mg orally at 8 hrly intervals; or single dose of 4 mg by slow IV or IM inj at induction of anaesthesia. Treatment, single dose of 4 mg by slow IV or IM inj.
Children: Prevention and treatment of chemotherapy- and radiotherapy-induced nausea and vomiting (Not licensed for radiotherapy-induced nausea and vomiting): By IV infusion over at least 15 minutes. 6 mth-18 yr, either 5 mg/square meter immediately before chemotherapy (8 mg if body surface area greater than 1.2 square meter), then given by mouth, or 150 mcg/kg immediately before chemotherapy (max single dose 8 mg) repeated every 4 hr for 2 further doses, then given by mouth; max total daily dose 32 mg. By mouth following IV administration. Oral dosing can start 12 hr after IV administration: 6 mth-18 yr, Body surface area less than 0.6 square meter or bodyweight 10 kg or less, 2 mg every 12 hr for up to 5 days (max total daily dose 32 mg); Body surface area 0.6-1.2 square meter or body-weight over 10 kg, 4 mg every 12 hr for up to 5 days (max total daily dose 32 mg); Body surface area greater than 1.2 square meter or body weight over 40 kg, 8 mg every 12 hr for up to 5 days (max total daily dose 32 mg).
Treatment and prevention of postoperative nausea and vomiting: By slow IV injection over at least 30 sec. 1 mth-18 yr, 100 mcg/kg (max 4 mg) as a single dose before, during, or after induction of anaesthesia.
One of the following licensed pharmacy from the nearest location will deliver Ondavell Injection 4 mg 5 Ampx2 mL. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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