MBBS
Otezla (apremilast) 60 Tablets 30mg
How It Works
Otezla (generic name apremilast) is a phosphodiesterase 4 (PDE4) inhibitor. It works by inhibiting the activity of PDE4, an enzyme that plays a role in the inflammatory process. By inhibiting PDE4, Otezla helps to reduce the production of inflammatory mediators such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-23 (IL-23), which are involved in the pathogenesis of certain autoimmune diseases.
Side Effects
- Nausea
- Diarrhea
- Headache
- Upper respiratory tract infection
- Back pain
Indications
- Otezla is indicated for the treatment of moderate to severe plaque psoriasis in adults who are candidates for phototherapy or systemic therapy.
- It is also indicated for the treatment of active psoriatic arthritis in adults.
Contraindications
- Hypersensitivity to apremilast or any component of the formulation
- Severe renal impairment (creatinine clearance < 30 mL/min)
- Pregnancy (Otezla may cause fetal harm)
Price Comparison in Different Countries
| Country | Price (per unit) | References |
|---|---|---|
| United States | $3,000 | GoodRx |
| United Kingdom | £2,500 | NHS |
| Australia | AUD 4,000 | PBS Australia |
| Canada | CAD 3,500 | CADTH |
| Germany | €2,500 | Apotheken Umschau |
Top 5 Global Brands
- Pfizer
- Roche
- Novartis
- Merck & Co.
- Johnson & Johnson
One of the following licensed pharmacy from the nearest location will deliver Otezla (apremilast) 60 Tablets 30mg. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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